| Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia M Konopleva, R Contractor, T Tsao, I Samudio, PP Ruvolo, S Kitada, ... Cancer cell 10 (5), 375-388, 2006 | 1172 | 2006 |
| Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction I Samudio, R Harmancey, M Fiegl, H Kantarjian, M Konopleva, B Korchin, ... The Journal of clinical investigation 120 (1), 142-156, 2010 | 769 | 2010 |
| Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML Z Zeng, Y Xi Shi, IJ Samudio, RY Wang, X Ling, O Frolova, M Levis, ... Blood, The Journal of the American Society of Hematology 113 (24), 6215-6224, 2009 | 616 | 2009 |
| Resistin promotes smooth muscle cell proliferation through activation of extracellular signal–regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways P Calabro, I Samudio, JT Willerson, ETH Yeh Circulation 110 (21), 3335-3340, 2004 | 483 | 2004 |
| MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy K Kojima, M Konopleva, IJ Samudio, M Shikami, M Cabreira-Hansen, ... Blood 106 (9), 3150-3159, 2005 | 451 | 2005 |
| Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML Z Zeng, DD Sarbassov, IJ Samudio, KWL Yee, MF Munsell, ... Blood 109 (8), 3509-3512, 2007 | 401 | 2007 |
| Mechanisms of transcriptional activation of bcl-2 gene expression by 17β-estradiol in breast cancer cells L Dong, W Wang, F Wang, M Stoner, JC Reed, M Harigai, I Samudio, ... Journal of Biological Chemistry 274 (45), 32099-32107, 1999 | 358 | 1999 |
| Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism I Samudio, M Fiegl, M Andreeff Cancer research 69 (6), 2163-2166, 2009 | 348 | 2009 |
| Effects of natural antioxidants in neurodegenerative disease SL Albarracin, B Stab, Z Casas, JJ Sutachan, I Samudio, J Gonzalez, ... Nutritional neuroscience 15 (1), 1-9, 2012 | 335 | 2012 |
| Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax) M Konopleva, J Watt, R Contractor, T Tsao, D Harris, Z Estrov, ... Cancer research 68 (9), 3413-3420, 2008 | 328 | 2008 |
| Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements E Castro-Rivera, I Samudio, S Safe Journal of Biological Chemistry 276 (33), 30853-30861, 2001 | 275 | 2001 |
| Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment S Kidd, L Caldwell, M Dietrich, I Samudio, EL Spaeth, K Watson, Y Shi, ... Cytotherapy 12 (5), 615-625, 2010 | 244 | 2010 |
| 3, 3′-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5 M Abdelrahim, K Newman, K Vanderlaag, I Samudio, S Safe Carcinogenesis 27 (4), 717-728, 2006 | 237 | 2006 |
| Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells S Safe, M Wormke, I Samudio Journal of mammary gland biology and neoplasia 5, 295-306, 2000 | 231 | 2000 |
| Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias Z Zeng, IJ Samudio, M Munsell, J An, Z Huang, E Estey, M Andreeff, ... Molecular cancer therapeutics 5 (12), 3113-3121, 2006 | 219 | 2006 |
| The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation I Samudio, M Fiegl, T McQueen, K Clise-Dwyer, M Andreeff Cancer research 68 (13), 5198-5205, 2008 | 200 | 2008 |
| Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor α and SP proteins M Stoner, M Wormke, B Saville, I Samudio, C Qin, M Abdelrahim, S Safe Oncogene 23 (5), 1052-1063, 2004 | 195 | 2004 |
| Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes P Matre, J Velez, R Jacamo, Y Qi, X Su, T Cai, SM Chan, A Lodi, ... Oncotarget 7 (48), 79722, 2016 | 168 | 2016 |
| CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure M Fiegl, I Samudio, K Clise-Dwyer, JK Burks, Z Mnjoyan, M Andreeff Blood, The Journal of the American Society of Hematology 113 (7), 1504-1512, 2009 | 156 | 2009 |
| Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells M Abdelrahim, I Samudio, R Smith, R Burghardt, S Safe Journal of Biological Chemistry 277 (32), 28815-28822, 2002 | 155 | 2002 |
