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Georgina Cox
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Intrinsic antibiotic resistance: mechanisms, origins, challenges and solutions
G Cox, GD Wright
International Journal of Medical Microbiology 303 (6-7), 287-292, 2013
6012013
A common platform for antibiotic dereplication and adjuvant discovery
G Cox, A Sieron, AM King, G De Pascale, AC Pawlowski, K Koteva, ...
Cell chemical biology 24 (1), 98-109, 2017
932017
Plazomicin retains antibiotic activity against most aminoglycoside modifying enzymes
G Cox, L Ejim, PJ Stogios, K Koteva, E Bordeleau, E Evdokimova, ...
ACS infectious diseases 4 (6), 980-987, 2018
912018
Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT (2 ″)-Ia
G Cox, PJ Stogios, A Savchenko, GD Wright
MBio 6 (1), e02180-14, 2015
522015
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid
G Cox, GS Thompson, HT Jenkins, F Peske, A Savelsbergh, MV Rodnina, ...
Proceedings of the National Academy of Sciences 109 (6), 2102-2107, 2012
482012
Inhibition of the ANT (2 ″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones
DR Hirsch, G Cox, MP D’Erasmo, T Shakya, C Meck, N Mohd, GD Wright, ...
Bioorganic & medicinal chemistry letters 24 (21), 4943-4947, 2014
452014
Rifampin phosphotransferase is an unusual antibiotic resistance kinase
PJ Stogios, G Cox, P Spanogiannopoulos, MC Pillon, N Waglechner, ...
Nature communications 7, 11343, 2016
442016
An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria
G Cox, K Koteva, GD Wright
Journal of Antimicrobial Chemotherapy 69 (7), 1844-1855, 2014
432014
Rox, a rifamycin resistance Enzyme with an unprecedented mechanism of action
K Koteva, G Cox, JK Kelso, MD Surette, HL Zubyk, L Ejim, P Stogios, ...
Cell chemical biology 25 (4), 403-412. e5, 2018
372018
Bacterial Anti-adhesives: Inhibition of Staphylococcus aureus Nasal Colonization
AC Leonard, LE Petrie, G Cox
ACS Infectious Diseases 5 (10), 1668-1681, 2019
262019
The evolutionary conservation of Escherichia coli drug efflux pumps supports physiological functions
T Teelucksingh, LK Thompson, G Cox
Journal of Bacteriology 202 (22), e00367-20, 2020
252020
tet(U)” Is Not a Tetracycline Resistance Determinant
JA Caryl, G Cox, S Trimble, AJ O'Neill
Antimicrobial agents and chemotherapy 56 (6), 3378-3379, 2012
232012
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis
PJ Stogios, G Cox, HL Zubyk, E Evdokimova, Z Wawrzak, GD Wright, ...
ACS chemical biology 13 (5), 1322-1332, 2018
152018
Old problems and new solutions: antibiotic alternatives in food animal production
C Stoica, G Cox
Canadian Journal of Microbiology 67 (6), 427-444, 2021
92021
Development and validation of a high-throughput whole cell assay to investigate Staphylococcus aureus adhesion to host ligands
LE Petrie, AC Leonard, J Murphy, G Cox
Journal of Biological Chemistry 295 (49), 16700-16712, 2020
82020
Resistance-guided discovery of elfamycin antibiotic producers with antigonococcal activity
V Yarlagadda, R Medina, TA Johnson, KP Koteva, G Cox, MN Thaker, ...
ACS Infectious Diseases 6 (12), 3163-3173, 2020
72020
Mutagenesis mapping of the protein-protein interaction underlying FusB-type fusidic acid resistance
G Cox, TA Edwards, AJ O'Neill
Antimicrobial agents and chemotherapy 57 (10), 4640-4644, 2013
72013
Antibiotic dereplication using the antibiotic resistance platform
HL Zubyk, G Cox, GD Wright
JoVE (Journal of Visualized Experiments), e60536, 2019
32019
A genetic platform to investigate the functions of bacterial drug efflux pumps
T Teelucksingh, LK Thompson, S Zhu, NM Kuehfuss, JA Goetz, SE Gilbert, ...
Nature Chemical Biology, 1-11, 2022
22022
Chinks in the Armor: Pathogenesis‐Based Strategies to Combat Bacterial Infections
AC Leonard, C Stoica, G Cox
Pathogenesis of Bacterial Infections in Animals, 99-116, 2022
2022
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Articles 1–20