Andrew Magis
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A wellness study of 108 individuals using personal, dense, dynamic data clouds
ND Price, AT Magis, JC Earls, G Glusman, R Levy, C Lausted, ...
Nature biotechnology 35 (8), 747, 2017
A small molecule inhibitor, 1, 2, 4, 5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth
VM Golubovskaya, C Nyberg, M Zheng, F Kweh, A Magis, D Ostrov, ...
Journal of medicinal chemistry 51 (23), 7405-7416, 2008
A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
SN Hochwald, C Nyberg, M Zheng, D Zheng, C Wood, NA Massoll, ...
Cell cycle 8 (15), 2435-2443, 2009
Noise contributions in an inducible genetic switch: a whole-cell simulation study
E Roberts, A Magis, JO Ortiz, W Baumeister, Z Luthey-Schulten
PLoS Comput Biol 7 (3), e1002010, 2011
Small-molecule Bcl2 BH4 antagonist for lung cancer therapy
B Han, D Park, R Li, M Xie, TK Owonikoko, G Zhang, GL Sica, C Ding, ...
Cancer cell 27 (6), 852-863, 2015
Small-molecule Bax agonists for cancer therapy
M Xin, R Li, M Xie, D Park, TK Owonikoko, GL Sica, PE Corsino, J Zhou, ...
Nature communications 5 (1), 1-11, 2014
A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl) -3, 5, 7-triaza-1-azoniatricyclo [ 3,7 ]decane; bromide …
VM Golubovskaya, S Figel, BT Ho, CP Johnson, M Yemma, G Huang, ...
Carcinogenesis 33 (5), 1004-1013, 2012
Blood metabolome predicts gut microbiome α-diversity in humans
T Wilmanski, N Rappaport, JC Earls, AT Magis, O Manor, J Lovejoy, ...
Nature biotechnology 37 (10), 1217-1228, 2019
Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast …
EV Kurenova, DL Hunt, D He, AT Magis, DA Ostrov, WG Cance
Journal of medicinal chemistry 52 (15), 4716-4724, 2009
Novel small-molecule inhibitors of Bcl-XL to treat lung cancer
D Park, AT Magis, R Li, TK Owonikoko, GL Sica, SY Sun, SS Ramalingam, ...
Cancer research 73 (17), 5485-5496, 2013
A multi-omic association study of trimethylamine N-oxide
O Manor, N Zubair, MP Conomos, X Xu, JE Rohwer, CE Krafft, JC Lovejoy, ...
Cell reports 24 (4), 935-946, 2018
Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth
VM Golubovskaya, B Ho, M Zheng, A Magis, D Ostrov, C Morrison, ...
BMC cancer 13 (1), 1-14, 2013
Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19
Y Su, D Chen, D Yuan, C Lausted, J Choi, CL Dai, V Voillet, VR Duvvuri, ...
Cell 183 (6), 1479-1495. e20, 2020
Identification of enoxacin as an inhibitor of osteoclast formation and bone resorption by structure-based virtual screening
DA Ostrov, AT Magis, TJ Wronski, EKL Chan, EJ Toro, RE Donatelli, ...
Journal of medicinal chemistry 52 (16), 5144-5151, 2009
The constitutive activation of Jak2-V617F is mediated by a π stacking mechanism involving phenylalanines 595 and 617
K Gnanasambandan, A Magis, PP Sayeski
Biochemistry 49 (46), 9972-9984, 2010
A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition
JP Cannon, RN Haire, AT Magis, DD Eason, KN Winfrey, JAH Prada, ...
Immunity 29 (2), 228-237, 2008
Targeting of the protein interaction site between FAK and IGF-1R
D Zheng, E Kurenova, D Ucar, V Golubovskaya, A Magis, D Ostrov, ...
Biochemical and biophysical research communications 388 (2), 301-305, 2009
Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth
J Sayyah, A Magis, DA Ostrov, RW Allan, RC Braylan, PP Sayeski
Molecular cancer therapeutics 7 (8), 2308-2318, 2008
Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy
G Chen, AT Magis, K Xu, D Park, SY David, TK Owonikoko, GL Sica, ...
The Journal of clinical investigation 128 (1), 500-516, 2018
A small-molecule inhibitor, 5'-O-Tritylthymidine, targets FAK And Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo
V M Golubovskaya, N L Palma, M Zheng, B Ho, A Magis, D Ostrov, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2013
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