Gregory B Whitfield
Gregory B Whitfield
Post-doctoral fellow, Université de Montréal
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Pseudomonas aeruginosa Alginate Overproduction Promotes Coexistence with Staphylococcus aureus in a Model of Cystic Fibrosis Respiratory Infection
DH Limoli, GB Whitfield, T Kitao, ML Ivey, MR Davis Jr, N Grahl, ...
MBio 8 (2), 10.1128/mbio. 00186-17, 2017
Enzymatic modifications of exopolysaccharides enhance bacterial persistence
GB Whitfield, LS Marmont, PL Howell
Frontiers in microbiology 6, 141808, 2015
Dimeric c-di-GMP is required for post-translational regulation of alginate production in Pseudomonas aeruginosa
JC Whitney, GB Whitfield, LS Marmont, P Yip, AM Neculai, YD Lobsanov, ...
Journal of Biological Chemistry 290 (20), 12451-12462, 2015
Characterization of the Pseudomonas aeruginosa glycoside hydrolase PslG reveals that its levels are critical for Psl polysaccharide biosynthesis and biofilm formation
P Baker, GB Whitfield, PJ Hill, DJ Little, MJ Pestrak, H Robinson, ...
Journal of Biological Chemistry 290 (47), 28374-28387, 2015
PelA and PelB proteins form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa
LS Marmont, GB Whitfield, JD Rich, P Yip, LB Giesbrecht, CA Stremick, ...
Journal of Biological Chemistry 292 (47), 19411-19422, 2017
Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation
GCL Wong, JD Antani, PP Lele, J Chen, B Nan, MJ Kühn, A Persat, JL Bru, ...
Physical biology 18 (5), 051501, 2021
A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries
C Bundalovic-Torma, GB Whitfield, LS Marmont, PL Howell, J Parkinson
PLoS computational biology 16 (4), e1007721, 2020
Pel polysaccharide biosynthesis requires an inner membrane complex comprised of PelD, PelE, PelF, and PelG
GB Whitfield, LS Marmont, A Ostaszewski, JD Rich, JC Whitney, ...
Journal of bacteriology 202 (8), 10.1128/jb. 00684-19, 2020
Oligomeric lipoprotein PelC guides Pel polysaccharide export across the outer membrane of Pseudomonas aeruginosa
LS Marmont, JD Rich, JC Whitney, GB Whitfield, H Almblad, H Robinson, ...
Proceedings of the National Academy of Sciences 114 (11), 2892-2897, 2017
Type IV Pili: dynamic bacterial nanomachines
CK Ellison, GB Whitfield, YV Brun
FEMS Microbiology Reviews 46 (2), fuab053, 2022
Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster
GB Whitfield, LS Marmont, C Bundalovic-Torma, E Razvi, EJ Roach, ...
PLoS Pathogens 16 (4), e1008281, 2020
Surface sensing stimulates cellular differentiation in Caulobacter crescentus
RA Snyder, CK Ellison, GB Severin, GB Whitfield, CM Waters, YV Brun
Proceedings of the National Academy of Sciences 117 (30), 17984-17991, 2020
Pseudomonas aeruginosa Uses c-di-GMP Phosphodiesterases RmcA and MorA To Regulate Biofilm Maintenance
S Katharios-Lanwermeyer, GB Whitfield, PL Howell, GA O’toole
MBio 12 (1), 10.1128/mbio. 03384-20, 2021
The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis
AA Gheorghita, F Wolfram, GB Whitfield, HM Jacobs, R Pfoh, SSY Wong, ...
Journal of Biological Chemistry 298 (2), 2022
PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide–dependent biofilm formation
LS Marmont, GB Whitfield, R Pfoh, RJ Williams, TE Randall, ...
Journal of Biological Chemistry 295 (34), 11949-11962, 2020
Structure of the AlgKX modification and secretion complex required for alginate production and biofilm attachment in Pseudomonas aeruginosa
AA Gheorghita, YE Li, EN Kitova, DT Bui, R Pfoh, KE Low, GB Whitfield, ...
Nature communications 13 (1), 7631, 2022
Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence
E Razvi, GB Whitfield, C Reichhardt, JE Dreifus, AR Willis, ...
npj Biofilms and Microbiomes 9 (1), 7, 2023
The matrix revisited: opening night for the Pel polysaccharide across eubacterial kingdoms
GB Whitfield, PL Howell
Microbiology insights 14, 1178636120988588, 2021
Pseudomonas aeruginosa alginate overproduction promotes coexistence with Staphylococcus aureus in a model of cystic fibrosis respiratory infection. mBio 8 (2): e00186-17
DH Limoli, GB Whitfield, T Kitao, ML Ivey, MR Davis, N Grahl, DA Hogan, ...
Crossref, Medline, CAS, 2017
Small molecule inhibition of an exopolysaccharide modification enzyme is a viable strategy to block Pseudomonas aeruginosa Pel biofilm formation
E Razvi, BR DiFrancesco, GA Wasney, ZA Morrison, J Tam, A Auger, ...
Microbiology Spectrum 11 (3), e00296-23, 2023
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