|Guidelines for the use and interpretation of assays for monitoring autophagy|
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
|The biology of cancer: metabolic reprogramming fuels cell growth and proliferation|
RJ DeBerardinis, JJ Lum, G Hatzivassiliou, CB Thompson
Cell metabolism 7 (1), 11-20, 2008
|Growth factor regulation of autophagy and cell survival in the absence of apoptosis|
JJ Lum, DE Bauer, M Kong, MH Harris, C Li, T Lindsten, CB Thompson
Cell 120 (2), 237-248, 2005
|Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma|
RK Amaravadi, D Yu, JJ Lum, T Bui, MA Christophorou, GI Evan, ...
The Journal of clinical investigation 117 (2), 326-336, 2007
|Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth|
M Buzzai, RG Jones, RK Amaravadi, JJ Lum, RJ DeBerardinis, F Zhao, ...
Cancer research 67 (14), 6745-6752, 2007
|Autophagy in metazoans: cell survival in the land of plenty|
JJ Lum, RJ DeBerardinis, CB Thompson
Nature reviews Molecular cell biology 6 (6), 439-448, 2005
|The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis|
JJ Lum, T Bui, M Gruber, JD Gordan, RJ DeBerardinis, KL Covello, ...
Genes & development 21 (9), 1037-1049, 2007
|Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis|
JJ Lum, OJ Cohen, Z Nie, JG Weaver, TS Gomez, XJ Yao, D Lynch, ...
The Journal of clinical investigation 111 (10), 1547-1554, 2003
|Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma|
XH Ma, S Piao, D Wang, QW Mcafee, KL Nathanson, JJ Lum, LZ Li, ...
Clinical cancer research 17 (10), 3478-3489, 2011
|Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth|
RJ DeBerardinis, JJ Lum, CB Thompson
Journal of Biological Chemistry 281 (49), 37372-37380, 2006
|Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation|
JJ Gruber, DS Zatechka, LR Sabin, J Yong, JJ Lum, M Kong, WX Zong, ...
Cell 138 (2), 328-339, 2009
|Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand|
DE Bauer, MH Harris, DR Plas, JJ Lum, PS Hammerman, JC Rathmell, ...
The FASEB journal 18 (11), 1303-1305, 2004
|Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming|
F Zhao, A Mancuso, TV Bui, X Tong, JJ Gruber, CR Swider, PV Sanchez, ...
Oncogene 29 (20), 2962-2972, 2010
|Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l|
JJ Lum, AA Pilon, J Sanchez-Dardon, BN Phenix, JE Kim, J Mihowich, ...
Journal of virology 75 (22), 11128-11136, 2001
|HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation|
Z Nie, BN Phenix, JJ Lum, A Alam, DH Lynch, B Beckett, PH Krammer, ...
Cell Death & Differentiation 9 (11), 1172-1184, 2002
|Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss|
BN Phenix, JJ Lum, Z Nie, J Sanchez-Dardon, AD Badley
Blood, The Journal of the American Society of Hematology 98 (4), 1078-1085, 2001
|Variability in Raman Spectra of Single Human Tumor Cells Cultured in vitro: Correlation with Cell Cycle and Culture Confluency|
Q Matthews, A Jirasek, J Lum, X Duan, AG Brolo
Applied spectroscopy 64 (8), 871-887, 2010
|Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity|
KN Townsend, LRK Hughson, K Schlie, VI Poon, A Westerback, JJ Lum
Immunological reviews 249 (1), 176-194, 2012
|Elimination of senescent neutrophils by TNF-related apoptosis-inducing ligand|
JJ Lum, G Bren, R McClure, AD Badley
The Journal of Immunology 175 (2), 1232-1238, 2005
|Mitochondrion-mediated apoptosis in HIV-1 infection|
AD Badley, T Roumier, JJ Lum, G Kroemer
Trends in pharmacological sciences 24 (6), 298-305, 2003