Julian J. Lum
Julian J. Lum
BC Cancer
Verified email at bccancer.bc.ca
TitleCited byYear
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
RJ DeBerardinis, JJ Lum, G Hatzivassiliou, CB Thompson
Cell metabolism 7 (1), 11-20, 2008
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
JJ Lum, DE Bauer, M Kong, MH Harris, C Li, T Lindsten, CB Thompson
Cell 120 (2), 237-248, 2005
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
RK Amaravadi, D Yu, JJ Lum, T Bui, MA Christophorou, GI Evan, ...
The Journal of clinical investigation 117 (2), 326-336, 2007
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
M Buzzai, RG Jones, RK Amaravadi, JJ Lum, RJ DeBerardinis, F Zhao, ...
Cancer research 67 (14), 6745-6752, 2007
Autophagy in metazoans: cell survival in the land of plenty
JJ Lum, RJ DeBerardinis, CB Thompson
Nature reviews Molecular cell biology 6 (6), 439-448, 2005
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
JJ Lum, T Bui, M Gruber, JD Gordan, RJ DeBerardinis, KL Covello, ...
Genes & development 21 (9), 1037-1049, 2007
Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
JJ Lum, OJ Cohen, Z Nie, JG Weaver, TS Gomez, XJ Yao, D Lynch, ...
The Journal of clinical investigation 111 (10), 1547-1554, 2003
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
XH Ma, S Piao, D Wang, QW Mcafee, KL Nathanson, JJ Lum, LZ Li, ...
Clinical cancer research 17 (10), 3478-3489, 2011
Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth
RJ DeBerardinis, JJ Lum, CB Thompson
Journal of Biological Chemistry 281 (49), 37372-37380, 2006
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation
JJ Gruber, DS Zatechka, LR Sabin, J Yong, JJ Lum, M Kong, WX Zong, ...
Cell 138 (2), 328-339, 2009
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand
DE Bauer, MH Harris, DR Plas, JJ Lum, PS Hammerman, JC Rathmell, ...
The FASEB journal 18 (11), 1303-1305, 2004
Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming
F Zhao, A Mancuso, TV Bui, X Tong, JJ Gruber, CR Swider, PV Sanchez, ...
Oncogene 29 (20), 2962-2972, 2010
Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l
JJ Lum, AA Pilon, J Sanchez-Dardon, BN Phenix, JE Kim, J Mihowich, ...
Journal of virology 75 (22), 11128-11136, 2001
HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation
Z Nie, BN Phenix, JJ Lum, A Alam, DH Lynch, B Beckett, PH Krammer, ...
Cell Death & Differentiation 9 (11), 1172-1184, 2002
Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss
BN Phenix, JJ Lum, Z Nie, J Sanchez-Dardon, AD Badley
Blood, The Journal of the American Society of Hematology 98 (4), 1078-1085, 2001
Variability in Raman Spectra of Single Human Tumor Cells Cultured in vitro: Correlation with Cell Cycle and Culture Confluency
Q Matthews, A Jirasek, J Lum, X Duan, AG Brolo
Applied spectroscopy 64 (8), 871-887, 2010
Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity
KN Townsend, LRK Hughson, K Schlie, VI Poon, A Westerback, JJ Lum
Immunological reviews 249 (1), 176-194, 2012
Elimination of senescent neutrophils by TNF-related apoptosis-inducing ligand
JJ Lum, G Bren, R McClure, AD Badley
The Journal of Immunology 175 (2), 1232-1238, 2005
Mitochondrion-mediated apoptosis in HIV-1 infection
AD Badley, T Roumier, JJ Lum, G Kroemer
Trends in pharmacological sciences 24 (6), 298-305, 2003
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Articles 1–20