| Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury K Zhao, GM Zhao, D Wu, Y Soong, AV Birk, PW Schiller, HH Szeto Journal of Biological Chemistry 279 (33), 34682-34690, 2004 | 916 | 2004 |
| Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta … PW Schiller, TM Nguyen, G Weltrowska, BC Wilkes, BJ Marsden, ... Proceedings of the National Academy of Sciences 89 (24), 11871-11875, 1992 | 297 | 1992 |
| A genetically encoded biosensor reveals location bias of opioid drug action M Stoeber, D Jullié, BT Lobingier, T Laeremans, J Steyaert, PW Schiller, ... Neuron 98 (5), 963-976. e5, 2018 | 278 | 2018 |
| Localization of immunoreactive synthetic atrial natriuretic factor (ANF) in the heart of various animal species. C Chapeau, J Gutkowska, PW Schiller, RW Milne, G Thibault, R Garcia, ... Journal of histochemistry & cytochemistry 33 (6), 541-550, 1985 | 263 | 1985 |
| Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogs: effect of conformational constraints on opiate receptor selectivity J DiMaio, TMD Nguyen, C Lemieux, PW Schiller Journal of medicinal chemistry 25 (12), 1432-1438, 1982 | 252 | 1982 |
| An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library CT Dooley, NN Chung, BC Wilkes, PW Schiller, JM Bidlack, ... Science 266 (5193), 2019-2022, 1994 | 230 | 1994 |
| MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1 H Zhu, Y Yang, Y Wang, J Li, PW Schiller, T Peng Cardiovascular research 92 (1), 75-84, 2011 | 228 | 2011 |
| The opioid μ agonist/δ antagonist DIPP-NH2 [Ψ] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats PW Schiller, ME Fundytus, L Merovitz, G Weltrowska, TMD Nguyen, ... Journal of medicinal chemistry 42 (18), 3520-3526, 1999 | 227 | 1999 |
| Characterization of specific receptors for atrial natriuretic factor in bovine adrenal zona glomerulosa A De Lean, J Gutkowska, N McNicoll, PW Schiller, M Cantin, J Genest Life sciences 35 (23), 2311-2318, 1984 | 226 | 1984 |
| Dermorphin analogs carrying an increased positive net charge in their" message" domain display extremely high. mu.-opioid receptor selectivity PW Schiller, NTM Dung, NN Chung, C Lemieux Journal of medicinal chemistry 32 (3), 698-703, 1989 | 209 | 1989 |
| Synthesis and in vitro opioid activity profiles of DALDA analogues PW Schiller, TMD Nguyen, I Berezowska, S Dupuis, G Weltrowska, ... European journal of medicinal chemistry 35 (10), 895-901, 2000 | 204 | 2000 |
| Transcellular transport of a highly polar 3+ net charge opioid tetrapeptide K Zhao, G Luo, GM Zhao, PW Schiller, HH Szeto Journal of Pharmacology and Experimental Therapeutics 304 (1), 425-432, 2003 | 202 | 2003 |
| Bi-or multifunctional opioid peptide drugs PW Schiller Life sciences 86 (15-16), 598-603, 2010 | 198 | 2010 |
| Structural basis for bifunctional peptide recognition at human δ-opioid receptor G Fenalti, NA Zatsepin, C Betti, P Giguere, GW Han, A Ishchenko, W Liu, ... Nature structural & molecular biology 22 (3), 265-268, 2015 | 192 | 2015 |
| Novel therapies targeting inner mitochondrial membrane—from discovery to clinical development HH Szeto, PW Schiller Pharmaceutical research 28, 2669-2679, 2011 | 190 | 2011 |
| TIPP [. psi.]: a highly potent and stable pseudopeptide. delta. opioid receptor antagonist with extraordinary. delta. selectivity PW Schiller, G Weltrowska, TMD Nguyen, BC Wilkes, NN Chung, ... Journal of medicinal chemistry 36 (21), 3182-3187, 1993 | 184 | 1993 |
| Attenuation of morphine tolerance and dependence with the highly selective δ-opioid receptor antagonist TIPP [ψ] ME Fundytus, PW Schiller, M Shapiro, G Weltrowska, TJ Coderre European journal of pharmacology 286 (1), 105-108, 1995 | 180 | 1995 |
| A cyclic enkephalin analog with high in vitro opiate activity. J DiMaio, PW Schiller Proceedings of the National Academy of Sciences 77 (12), 7162-7166, 1980 | 179 | 1980 |
| Unsulfated C-terminal 7-peptide of cholecystokinin: a new ligand of the opiate receptor PW Schiller, A Lipton, DF Horrobin, M Bodanszky Biochemical and biophysical research communications 85 (4), 1332-1338, 1978 | 159 | 1978 |
| The TIPP opioid peptide family: development of δ antagonists, δ agonists, and mixed μ agonist/δ antagonists PW Schiller, G Weltrowska, I Berezowska, TMD Nguyen, BC Wilkes, ... Peptide Science 51 (6), 411-425, 1999 | 141 | 1999 |
Ralf SchmidtEMD SeronoVerified email at emdserono.com
