Daniel Schramek
Daniel Schramek
PI & Assit. Prof. Mount Sinai Hospital/University of Toronto
Verified email at lunenfeld.ca - Homepage
TitleCited byYear
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ...
Nature 468 (7320), 98, 2010
4532010
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate
JA Pospisilik, D Schramek, H Schnidar, SJF Cronin, NT Nehme, X Zhang, ...
Cell 140 (1), 148-160, 2010
2952010
Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection
SJF Cronin, NT Nehme, S Limmer, S Liegeois, JA Pospisilik, D Schramek, ...
Science 325 (5938), 340-343, 2009
2922009
A dual role for autophagy in a murine model of lung cancer
S Rao, L Tortola, T Perlot, G Wirnsberger, M Novatchkova, R Nitsch, ...
Nature communications 5, 3056, 2014
2252014
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene
GG Neely, A Hess, M Costigan, AC Keene, S Goulas, M Langeslag, ...
Cell 143 (4), 628-638, 2010
2172010
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells
U Elling, J Taubenschmid, G Wirnsberger, R O'Malley, SP Demers, ...
Cell stem cell 9 (6), 563-574, 2011
2032011
Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas
D Schramek, A Sendoel, JP Segal, S Beronja, E Heller, D Oristian, ...
Science 343 (6168), 309-313, 2014
1552014
Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein
T Brummer, D Schramek, VM Hayes, HL Bennett, CE Caldon, ...
Journal of Biological Chemistry 281 (1), 626-637, 2006
1152006
Translation from unconventional 5′ start sites drives tumour initiation
A Sendoel, JG Dunn, EH Rodriguez, S Naik, NC Gomez, B Hurwitz, ...
Nature 541 (7638), 494, 2017
1102017
RANKL/RANK—beyond bones
R Hanada, T Hanada, V Sigl, D Schramek, JM Penninger
Journal of Molecular Medicine 89 (7), 647-656, 2011
952011
Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor
P Timpson, DK Lynch, D Schramek, F Walker, RJ Daly
Cancer research 65 (8), 3273-3280, 2005
942005
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis
B Grabner, D Schramek, KM Mueller, HP Moll, J Svinka, T Hoffmann, ...
Nature communications 6, 6285, 2015
862015
The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression
D Schramek, A Kotsinas, A Meixner, T Wada, U Elling, JA Pospisilik, ...
Nature genetics 43 (3), 212, 2011
852011
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ...
Development 140 (7), 1397-1401, 2013
692013
RANKL/RANK control Brca1 mutation-driven mammary tumors
V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ...
Cell research 26 (7), 761, 2016
682016
Phosphorylation‐dependent binding of 14‐3‐3 terminates signalling by the Gab2 docking protein
T Brummer, M Larance, MTH Abreu, RJ Lyons, P Timpson, CH Emmerich, ...
The EMBO journal 27 (17), 2305-2316, 2008
572008
Disruption of the growth hormone—signal transducer and activator of transcription 5—insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of …
L Blaas, JW Kornfeld, D Schramek, M Musteanu, G Zollner, J Gumhold, ...
Hepatology 51 (4), 1319-1326, 2010
542010
Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors
FU Wöhrle, S Halbach, K Aumann, S Schwemmers, S Braun, P Auberger, ...
Leukemia 27 (1), 118, 2013
512013
RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis
D Schramek, V Sigl, JM Penninger
Trends in Endocrinology & Metabolism 22 (5), 188-194, 2011
442011
A new integrative indicator to assess crop genetic diversity
C Bonneuil, R Goffaux, I Bonnin, P Montalent, C Hamon, F Balfourier, ...
Ecological Indicators 23, 280-289, 2012
422012
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