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Han Chen
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC ...
Nature genetics 44 (9), 981-990, 2012
21292012
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12302016
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
RA Scott, V Lagou, RP Welch, E Wheeler, ME Montasser, J Luan, R Mägi, ...
Nature genetics 44 (9), 991-1005, 2012
915*2012
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
AK Manning, MF Hivert, RA Scott, JL Grimsby, N Bouatia-Naji, H Chen, ...
Nature genetics 44 (6), 659-669, 2012
909*2012
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nature genetics 46 (3), 234-244, 2014
8912014
An expanded genome-wide association study of type 2 diabetes in Europeans
RA Scott, LJ Scott, R Mägi, L Marullo, KJ Gaulton, M Kaakinen, ...
Diabetes 66 (11), 2888-2902, 2017
7132017
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ...
Diabetes 60 (10), 2624-2634, 2011
4472011
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
430*2015
Control for population structure and relatedness for binary traits in genetic association studies via logistic mixed models
H Chen, C Wang, MP Conomos, AM Stilp, Z Li, T Sofer, AA Szpiro, ...
The American Journal of Human Genetics 98 (4), 653-666, 2016
3992016
Genetic association testing using the GENESIS R/Bioconductor package
SM Gogarten, T Sofer, H Chen, C Yu, JA Brody, TA Thornton, KM Rice, ...
Bioinformatics 35 (24), 5346-5348, 2019
2792019
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
C Liu, AT Kraja, JA Smith, JA Brody, N Franceschini, JC Bis, K Rice, ...
Nature genetics 48 (10), 1162-1170, 2016
267*2016
Sequence kernel association test for quantitative traits in family samples
H Chen, JB Meigs, J Dupuis
Genetic epidemiology 37 (2), 196-204, 2013
2442013
A method of moments estimator for random effect multivariate meta-analysis
H Chen, AK Manning, J Dupuis
Biometrics 68 (4), 1278-1284, 2012
2082012
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies
R Joehanes, X Zhang, T Huan, C Yao, S Ying, QT Nguyen, CY Demirkale, ...
Genome biology 18, 1-24, 2017
1732017
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale
X Li, Z Li, H Zhou, SM Gaynor, Y Liu, H Chen, R Sun, R Dey, DK Arnett, ...
Nature genetics 52 (9), 969-983, 2020
1542020
Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole-genome sequencing studies
H Chen, JE Huffman, JA Brody, C Wang, S Lee, Z Li, SM Gogarten, ...
The American Journal of Human Genetics 104 (2), 260-274, 2019
1242019
Genetic associations with obstructive sleep apnea traits in Hispanic/Latino Americans
BE Cade, H Chen, AM Stilp, KJ Gleason, T Sofer, S Ancoli-Israel, R Arens, ...
American journal of respiratory and critical care medicine 194 (7), 886-897, 2016
1232016
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. An expanded genome-wide association study of type 2 diabetes in Europeans
RA Scott, LJ Scott, R Mägi, L Marullo, KJ Gaulton, M Kaakinen, ...
Diabetes 66 (11), 2888-2902, 2017
1002017
Test for rare variants by environment interactions in sequencing association studies
X Lin, S Lee, MC Wu, C Wang, H Chen, Z Li, X Lin
Biometrics 72 (1), 156-164, 2016
892016
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci
GA Walford, S Gustafsson, D Rybin, A Stančáková, H Chen, CT Liu, ...
Diabetes 65 (10), 3200-3211, 2016
862016
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