Specificity of Intersubunit General Anesthetic-binding Sites in the Transmembrane Domain of the Human α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor*♦ DC Chiara, SS Jayakar, X Zhou, X Zhang, PY Savechenkov, KS Bruzik, ... Journal of Biological Chemistry 288 (27), 19343-19357, 2013 | 143 | 2013 |
Multiple Propofol-binding Sites in a γ-Aminobutyric Acid Type A Receptor (GABAAR) Identified Using a Photoreactive Propofol Analog*♦ SS Jayakar, X Zhou, DC Chiara, Z Dostalova, PY Savechenkov, KS Bruzik, ... Journal of Biological Chemistry 289 (40), 27456-27468, 2014 | 118 | 2014 |
Anion Binding Modes in meso-Substituted Hexapyrrolic Calix[4]pyrrole Isomers KC Chang, T Minami, P Koutnik, PY Savechenkov, Y Liu, ... Journal of the American Chemical Society 136 (4), 1520-1525, 2014 | 57 | 2014 |
p-(4-Azipentyl)propofol: A Potent Photoreactive General Anesthetic Derivative of Propofol DS Stewart, PY Savechenkov, Z Dostalova, DC Chiara, R Ge, DE Raines, ... Journal of medicinal chemistry 54 (23), 8124-8135, 2011 | 51 | 2011 |
Allyl m-Trifluoromethyldiazirine Mephobarbital: An Unusually Potent Enantioselective and Photoreactive Barbiturate General Anesthetic PY Savechenkov, X Zhang, DC Chiara, DS Stewart, R Ge, X Zhou, ... Journal of medicinal chemistry 55 (14), 6554-6565, 2012 | 48 | 2012 |
Anion sensing by fluorescent expanded calixpyrroles M Pushina, P Koutnik, R Nishiyabu, T Minami, P Savechenkov, ... Chemistry–A European Journal 24 (19), 4879-4884, 2018 | 35 | 2018 |
Positive and negative allosteric modulation of an α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor by binding to a site in the transmembrane domain at the γ+-β− interface SS Jayakar, X Zhou, PY Savechenkov, DC Chiara, R Desai, KS Bruzik, ... Journal of Biological Chemistry 290 (38), 23432-23446, 2015 | 29 | 2015 |
Identifying barbiturate binding sites in a nicotinic acetylcholine receptor with [3H] allyl m-trifluoromethyldiazirine mephobarbital, a photoreactive barbiturate AK Hamouda, DS Stewart, DC Chiara, PY Savechenkov, KS Bruzik, ... Molecular Pharmacology 85 (5), 735-746, 2014 | 28 | 2014 |
Identifying drugs that bind selectively to intersubunit general anesthetic sites in the α1β3γ2 GABAAR transmembrane domain SS Jayakar, X Zhou, DC Chiara, C Jarava-Barrera, PY Savechenkov, ... Molecular pharmacology 95 (6), 615-628, 2019 | 25 | 2019 |
General anesthetic binding sites in human α4β3δ γ-aminobutyric acid type A receptors (GABAARs) DC Chiara, Y Jounaidi, X Zhou, PY Savechenkov, KS Bruzik, KW Miller, ... Journal of Biological Chemistry 291 (51), 26529-26539, 2016 | 25 | 2016 |
Reactions of Vinyl Type Carbocations Generated in Fluorosulfonic Acid with Benzene Derivatives. New Synthesis of Alkyl 3,3-Diarylpropenoates PY Savechenkov, AP Rudenko, AV Vasil'ev, GKR Fukin Russ. J. Org. Chem. 41, 1316–1328, 2005 | 22 | 2005 |
Protonation of 3-Arylpropynoic Acid Derivatives in Superacids. S Walspurger, AV Vasil’ev, J Sommer, P Pale, ... Russ. J. Org. Chem. 41, 1485–1492, 2005 | 22 | 2005 |
Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands PY Savechenkov, DC Chiara, R Desai, AT Stern, X Zhou, AM Ziemba, ... European journal of medicinal chemistry 136, 334-347, 2017 | 15 | 2017 |
Binding site location on GABAA receptors determines whether mixtures of intravenous general anaesthetics interact synergistically or additively in vivo DE Kent, PY Savechenkov, KS Bruzik, KW Miller British Journal of Pharmacology 176 (24), 4760-4772, 2019 | 10 | 2019 |
A Novel Dimerization of Methyl p-Tolylpropynoate in Fluorosulfonic Acid with Conservation of the Triple Bond PY Savechenkov, AP Rudenko, AV Vasil’ev Russ. J. Org. Chem. 40, 1065–1066, 2004 | 10 | 2004 |
Contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the α1β3γ2L GABAA receptor account for their in vivo effects R Desai, PY Savechenkov, D Zolkowska, RL Ge, MA Rogawski, KS Bruzik, ... The Journal of physiology 593 (22), 4943-4961, 2015 | 9 | 2015 |
Oxidation of aromatic compounds: XII. Regio- and stereoselective oxidative dimerization of alkyl 3-Arylpropynoates in the system CF3CO2H-CH2Cl2-PbO2 PY Savechenkov, AV Vasil’ev, AP Rudenko Russ. J. Org. Chem. 40, 1279–1283, 2004 | 9 | 2004 |
Nitration of Phenylpropiolic acid derivatives in HSO3F and reactions of vinyl type cations formed therefrom PY Savechenkov, AP Rudenko, AV Vasil’ev Russ. J. Org. Chem. 40, 1633–1637, 2004 | 9 | 2004 |
Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors B Wu, SS Jayakar, X Zhou, K Titterton, DC Chiara, AL Szabo, ... European journal of medicinal chemistry 162, 810-824, 2019 | 7 | 2019 |
Stereoselective synthesis of methyl 3,3-Diarylpropenoates AP Rudenko, PY Savechenkov, AV Vasil’ev Russ. J. Org. Chem. 40, 1377–1378, 2004 | 6 | 2004 |