A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family N Bocquet, L Prado de Carvalho, J Cartaud, J Neyton, C Le Poupon, ... Nature 445 (7123), 116-119, 2007 | 350 | 2007 |
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites N Le Novère, T Grutter, JP Changeux Proceedings of the National Academy of Sciences 99 (5), 3210-3215, 2002 | 342 | 2002 |
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism A Taly, M Delarue, T Grutter, M Nilges, N Le Novere, PJ Corringer, ... Biophysical journal 88 (6), 3954-3965, 2005 | 233 | 2005 |
Nicotinic receptors in wonderland T Grutter, JP Changeux Trends in biochemical sciences 26 (8), 459-463, 2001 | 231 | 2001 |
Update of P2X receptor properties and their pharmacology: IUPHAR Review 30 P Illes, CE Müller, KA Jacobson, T Grutter, A Nicke, SJ Fountain, ... British Journal of Pharmacology 178 (3), 489-514, 2021 | 212 | 2021 |
Ligand-gated ion channels: new insights into neurological disorders and ligand recognition D Lemoine, R Jiang, A Taly, T Chataigneau, A Specht, T Grutter Chemical reviews 112 (12), 6285-6318, 2012 | 184 | 2012 |
Molecular tuning of fast gating in pentameric ligand-gated ion channels T Grutter, LP de Carvalho, V Dufresne, A Taly, SJ Edelstein, JP Changeux Proceedings of the National Academy of Sciences 102 (50), 18207-18212, 2005 | 136 | 2005 |
Molecular structure and function of P2X receptors C Habermacher, K Dunning, T Chataigneau, T Grutter Neuropharmacology 104, 18-30, 2016 | 126 | 2016 |
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors A Taly, PJ Corringer, T Grutter, LP de Carvalho, M Karplus, JP Changeux Proceedings of the National Academy of Sciences 103 (45), 16965-16970, 2006 | 109 | 2006 |
On the permeation of large organic cations through the pore of ATP-gated P2X receptors M Harkat, L Peverini, AH Cerdan, K Dunning, J Beudez, A Martz, ... Proceedings of the National Academy of Sciences 114 (19), E3786-E3795, 2017 | 107 | 2017 |
Tightening of the ATP‐binding sites induces the opening of P2X receptor channels R Jiang, A Taly, D Lemoine, A Martz, O Cunrath, T Grutter The EMBO Journal 31 (9), 2134-2143, 2012 | 92 | 2012 |
Moving through the gate in ATP-activated P2X receptors R Jiang, A Taly, T Grutter Trends in biochemical sciences 38 (1), 20-29, 2013 | 83 | 2013 |
Exploring the ATP-binding site of P2X receptors T Chataigneau, D Lemoine, T Grutter Frontiers in cellular neuroscience 7, 273, 2013 | 78 | 2013 |
Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor É Lörinczi, Y Bhargava, SF Marino, A Taly, K Kaczmarek-Hájek, ... Proceedings of the National Academy of Sciences 109 (28), 11396-11401, 2012 | 78 | 2012 |
An H‐bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors T Grutter, LP de Carvalho, N Le Novère, PJ Corringer, S Edelstein, ... The EMBO Journal, 2003 | 75 | 2003 |
Optical control of an ion channel gate D Lemoine, C Habermacher, A Martz, PF Méry, N Bouquier, F Diverchy, ... Proceedings of the National Academy of Sciences 110 (51), 20813-20818, 2013 | 74 | 2013 |
Agonist trapped in ATP-binding sites of the P2X2 receptor R Jiang, D Lemoine, A Martz, A Taly, S Gonin, L Prado de Carvalho, ... Proceedings of the National Academy of Sciences 108 (22), 9066-9071, 2011 | 60 | 2011 |
Cysteine mutants as chemical sensors for ligand–receptor interactions B Foucaud, P Perret, T Grutter, M Goeldner Trends in pharmacological sciences 22 (4), 170-173, 2001 | 52 | 2001 |
Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel C Habermacher, A Martz, N Calimet, D Lemoine, L Peverini, A Specht, ... Elife 5, e11050, 2016 | 51 | 2016 |
New insights into permeation of large cations through ATP-gated P2X receptors L Peverini, J Beudez, K Dunning, T Chataigneau, T Grutter Frontiers in molecular neuroscience 11, 265, 2018 | 49 | 2018 |