David Litchfield
David Litchfield
Professor of Biochemistry & Professor of Oncology, Western University, London, Ontario, CANADA
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Cited by
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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death
DW Litchfield
Biochemical Journal 369 (1), 1-15, 2003
Premature p34cdc2 activation required for apoptosis
L Shi, WK Nishioka, J Th'ng, EM Bradbury, DW Litchfield, AH Greenberg
Science 263 (5150), 1143-1145, 1994
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
B Lüscher, E Christenson, DW Litchfield, EG Krebs, RN Eisenman
Nature 344 (6266), 517-522, 1990
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation
H Kleine, E Poreba, K Lesniewicz, PO Hassa, MO Hottiger, DW Litchfield, ...
Molecular cell 32 (1), 57-69, 2008
Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2
JS Duncan, DW Litchfield
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (1), 33-47, 2008
Solution structure of the tetrameric minimum transforming domain of p53
W Lee, TS Harvey, Y Yin, P Yau, D Litchfield, CH Arrowsmith
Nature structural biology 1 (12), 877-890, 1994
Protein kinase CK2 in health and disease: From birth to death: the role of protein kinase CK2 in the regulation of cell proliferation and survival
NA St-Denis, DW Litchfield
Cellular and Molecular Life Sciences 66, 1817-1829, 2009
EGF-induced ERK activation promotes CK2-mediated disassociation of α-catenin from β-catenin and transactivation of β-catenin
H Ji, J Wang, H Nika, D Hawke, S Keezer, Q Ge, B Fang, X Fang, D Fang, ...
Molecular cell 36 (4), 547-559, 2009
The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2β
AC Bibby, DW Litchfield
International journal of biological sciences 1 (2), 67, 2005
Casein kinase II in signal transduction and cell cycle regulation
DW Litchfield, B Lüscher
Reversible Protein Phosphorylation in Cell Regulation, 187-199, 1993
Isolation and characterization of human cDNA clones encoding the. alpha. and the. alpha.'subunits of casein kinase II
FJ Lozeman, DW Litchfield, C Piening, K Takio, KA Walsh, EG Krebs
Biochemistry 29 (36), 8436-8447, 1990
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.
TA Haystead, JE Weiel, DW Litchfield, Y Tsukitani, EH Fischer, EG Krebs
Journal of Biological Chemistry 265 (27), 16571-16580, 1990
Order or chaos? An evaluation of the regulation of protein kinase CK2
MEK Olsten, DW Litchfield
Biochemistry and cell biology 82 (6), 681-693, 2004
Phosphorylation of the beta subunit of casein kinase II in human A431 cells. Identification of the autophosphorylation site and a site phosphorylated by p34cdc2.
DW Litchfield, FJ Lozeman, MF Cicirelli, M Harrylock, LH Ericsson, ...
Journal of Biological Chemistry 266 (30), 20380-20389, 1991
Tra1p is a component of the yeast Ada· Spt transcriptional regulatory complexes
A Saleh, D Schieltz, N Ting, SB McMahon, DW Litchfield, JR Yates, ...
Journal of Biological Chemistry 273 (41), 26559-26565, 1998
Phosphorylation of casein kinase II by p34cdc2 in vitro and at mitosis.
DW Litchfield, B Lüscher, FJ Lozeman, RN Eisenman, EG Krebs
Journal of Biological Chemistry 267 (20), 13943-13951, 1992
Interactions between the Subunits of Casein Kinase II∗
RD Gietz, KC Graham, DW Litchfield
Journal of Biological Chemistry 270 (22), 13017-13021, 1995
Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder
Y Bian, L Li, M Dong, X Liu, T Kaneko, K Cheng, H Liu, C Voss, X Cao, ...
Nature chemical biology 12 (11), 959-966, 2016
Casein kinase II as a potentially important enzyme concerned with signal transduction
EG Krebs, RN Eisenman, EA Kijenzel, DW Litchfield, FJ Lozeman, ...
Cold Spring Harbor Symposia on Quantitative Biology 53, 77-84, 1988
Enzymatic site‐specific functionalization of protein methyltransferase substrates with alkynes for click labeling
W Peters, S Willnow, M Duisken, H Kleine, T Macherey, KE Duncan, ...
Angewandte Chemie International Edition 49 (30), 5170-5173, 2010
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