Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase L Li, X Liu, W Yang, F Xu, W Wang, L Feng, M Bartlam, L Wang, Z Rao Journal of molecular biology 376 (2), 453-465, 2008 | 218 | 2008 |
Crystal structure of the human CNOT6L nuclease domain reveals strict poly (A) substrate specificity H Wang, M Morita, X Yang, T Suzuki, W Yang, J Wang, K Ito, Q Wang, ... The EMBO journal 29 (15), 2566-2576, 2010 | 114 | 2010 |
A Highly Active Single‐Mutation Variant of P450BM3 (CYP102A1) CJC Whitehouse, SG Bell, W Yang, JA Yorke, CF Blanford, AJF Strong, ... ChemBioChem 10 (10), 1654-1656, 2009 | 98 | 2009 |
Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444 W Yang, SG Bell, H Wang, W Zhou, N Hoskins, A Dale, M Bartlam, ... Journal of biological chemistry 285 (35), 27372-27384, 2010 | 90 | 2010 |
Structural Basis for the Properties of Two Single‐Site Proline Mutants of CYP102A1 (P450BM3) CJC Whitehouse, W Yang, JA Yorke, BC Rowlatt, AJF Strong, CF Blanford, ... ChemBioChem 11 (18), 2549-2556, 2010 | 89 | 2010 |
Simple yet functional phosphate-loop proteins ML Romero Romero, F Yang, YR Lin, A Toth-Petroczy, IN Berezovsky, ... Proceedings of the National Academy of Sciences 115 (51), E11943-E11950, 2018 | 85 | 2018 |
A macrocyclic peptide ligand binds the oncogenic microRNA-21 precursor and suppresses Dicer processing GV Matthew D. Shortridge, Matthew J. Walker, Tom Pavelitz, Yu Chen, Wen Yang ACS Chem Biol 12 (6), 1611-1620, 2017 | 68 | 2017 |
Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity X Yang, M Morita, H Wang, T Suzuki, W Yang, Y Luo, C Zhao, Y Yu, ... Nucleic acids research 36 (21), 6872-6881, 2008 | 62 | 2008 |
Investigation of the substrate range of CYP199A4: Modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering SG Bell, R Zhou, W Yang, ABH Tan, AS Gentleman, LL Wong, W Zhou Chemistry–A European Journal 18 (52), 16677-16688, 2012 | 59 | 2012 |
The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site SG Bell, W Yang, ABH Tan, R Zhou, EOD Johnson, A Zhang, W Zhou, ... Dalton Transactions 41 (28), 8703-8714, 2012 | 56 | 2012 |
Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD PL Hsu, F Yang, W Smith-Kinnaman, W Yang, JE Song, AL Mosley, ... Journal of molecular biology 426 (16), 2970-2981, 2014 | 53 | 2014 |
Structure, electronic properties and catalytic behaviour of an activity-Enhancing CYP102A1 (P450 BM3) Variant CJC Whitehouse, W Yang, JA Yorke, HG Tufton, LCI Ogilvie, SG Bell, ... Dalton Transactions 40 (40), 10383-10396, 2011 | 46 | 2011 |
Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins VG Chen Y, Yang F, Zubovic L, Pavelitz T, Yang W, Godin K, Walker M, Zheng S ... Nat Chem Biol 12 (9), 717-723, 2016 | 45 | 2016 |
Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex X Wang, Z Lou, X Dong, W Yang, Y Peng, B Yin, Y Gong, J Yuan, W Zhou, ... Journal of molecular biology 390 (3), 530-537, 2009 | 42 | 2009 |
Crystal structure of hyperthermophilic endo-β-1, 4-glucanase: implications for catalytic mechanism and thermostability B Zheng, W Yang, X Zhao, Y Wang, Z Lou, Z Rao, Y Feng Journal of Biological Chemistry 287 (11), 8336-8346, 2012 | 40 | 2012 |
The structure of CYP101D2 unveils a potential path for substrate entry into the active site W Yang, SG Bell, H Wang, W Zhou, M Bartlam, LL Wong, Z Rao Biochemical Journal 433 (1), 85-93, 2011 | 39 | 2011 |
Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444 M Ma, SG Bell, W Yang, Y Hao, NH Rees, M Bartlam, W Zhou, LL Wong, ... ChemBioChem 12 (1), 88-99, 2011 | 36 | 2011 |
Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3′-end processing signals W Yang, PL Hsu, F Yang, JE Song, G Varani Nucleic Acids Research 46 (2), 493-503, 2018 | 35 | 2018 |
Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme SG Bell, W Yang, JA Yorke, W Zhou, H Wang, J Harmer, R Copley, ... Acta Crystallographica Section D: Biological Crystallography 68 (3), 277-291, 2012 | 35 | 2012 |
Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity Y Xu, X Li, R Li, S Li, H Ni, H Wang, H Xu, W Zhou, PEJ Saris, W Yang, ... Acta Crystallographica Section D: Biological Crystallography 70 (6), 1499-1505, 2014 | 30 | 2014 |