Stefan Gross
Stefan Gross
Agios Pharmaceuticals Ore Pharmaceuticals Tufts University
Verified email at agios.com
Title
Cited by
Cited by
Year
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ...
Nature 462 (7274), 739-744, 2009
30632009
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation
F Wang, J Travins, B DeLaBarre, V Penard-Lacronique, S Schalm, ...
Science 340 (6132), 622-626, 2013
6732013
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
S Gross
Journal of Experimental Medicine 207 (2), 339-334, 2010
6572010
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
P Koivunen, S Lee, CG Duncan, G Lopez, G Lu, S Ramkissoon, ...
Nature 483 (7390), 484-488, 2012
6062012
Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast
MM Kessler, MF Henry, E Shen, J Zhao, S Gross, PA Silver, CL Moore
Genes & development 11 (19), 2545-2556, 1997
2601997
Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo
J Popovici-Muller, JO Saunders, FG Salituro, JM Travins, S Yan, F Zhao, ...
ACS medicinal chemistry letters 3 (10), 850-855, 2012
1652012
Coupling of termination, 3′ processing, and mRNA export
CM Hammell, S Gross, D Zenklusen, CV Heath, F Stutz, C Moore, ...
Molecular and cellular biology 22 (18), 6441-6457, 2002
1592002
AG-221, a first-in-class therapy targeting acute myeloid leukemia harboring oncogenic IDH2 mutations
K Yen, J Travins, F Wang, MD David, E Artin, K Straley, A Padyana, ...
Cancer discovery 7 (5), 478-493, 2017
1532017
Small molecule activation of PKM2 in cancer cells induces serine auxotrophy
C Kung, J Hixon, S Choe, K Marks, S Gross, E Murphy, B DeLaBarre, ...
Chemistry & biology 19 (9), 1187-1198, 2012
1242012
MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis
K Marjon, MJ Cameron, P Quang, MF Clasquin, E Mandley, K Kunii, ...
Cell reports 15 (3), 574-587, 2016
1172016
Full-length human glutaminase in complex with an allosteric inhibitor
B DeLaBarre, S Gross, C Fang, Y Gao, A Jha, F Jiang, J Song J, W Wei, ...
Biochemistry 50 (50), 10764-10770, 2011
1142011
Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I
S Gross, C Moore
Proceedings of the National Academy of Sciences 98 (11), 6080-6085, 2001
1052001
Discovery of AG-120 (Ivosidenib): a first-in-class mutant IDH1 inhibitor for the treatment of IDH1 mutant cancers
J Popovici-Muller, RM Lemieux, E Artin, JO Saunders, FG Salituro, ...
ACS medicinal chemistry letters 9 (4), 300-305, 2018
1012018
Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3′-end formation
S Gross, CL Moore
Molecular and cellular biology 21 (23), 8045-8055, 2001
992001
Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1
MI Davis, S Gross, M Shen, KS Straley, R Pragani, WA Lea, ...
Journal of Biological Chemistry 289 (20), 13717-13725, 2014
652014
Mutant IDH is sufficient to initiate enchondromatosis in mice
M Hirata, M Sasaki, RA Cairns, S Inoue, V Puviindran, WY Li, BE Snow, ...
Proceedings of the National Academy of Sciences 112 (9), 2829-2834, 2015
592015
ALDH2 (E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis
S Jin, J Chen, L Chen, G Histen, Z Lin, S Gross, J Hixon, Y Chen, C Kung, ...
Proceedings of the National Academy of Sciences 112 (29), 9088-9093, 2015
412015
Effects of the ACE2 inhibitor GL1001 on acute dextran sodium sulfate-induced colitis in mice
JJ Byrnes, S Gross, C Ellard, K Connolly, S Donahue, D Picarella
Inflammation Research 58 (11), 819-827, 2009
382009
Methods and compositions for cell-proliferation-related disorders
L Dang, V Fantin, S Gross, HG Jang, S Jin, FG Salituro, JO Saunders, ...
US Patent App. 13/256,396, 2012
372012
The Uba2 and Ufd1 proteins of Saccharomyces cerevisiae interact with poly (A) polymerase and affect the polyadenylation activity of cell extracts
M Del Olmo, N Mizrahi, S Gross, CL Moore
Molecular and General Genetics MGG 255 (2), 209-218, 1997
361997
The system can't perform the operation now. Try again later.
Articles 1–20