Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins DM Engelman, TA Steitz, A Goldman Annual review of biophysics and biophysical chemistry 15 (1), 321-353, 1986 | 1942 | 1986 |
Membrane protein folding and oligomerization: the two-stage model JL Popot, DM Engelman Biochemistry 29 (17), 4031-4037, 1990 | 1197 | 1990 |
A transmembrane helix dimer: structure and implications KR MacKenzie, JH Prestegard, DM Engelman Science 276 (5309), 131-133, 1997 | 1150 | 1997 |
Membranes are more mosaic than fluid DM Engelman Nature 438 (7068), 578-580, 2005 | 1124 | 2005 |
The GxxxG motif: a framework for transmembrane helix-helix association WP Russ, DM Engelman Journal of molecular biology 296 (3), 911-919, 2000 | 1103 | 2000 |
The spontaneous insertion of proteins into and across membranes: the helical hairpin hypothesis DM Engelman, TA Steitz Cell 23 (2), 411-422, 1981 | 1079 | 1981 |
Lipid bilayer thickness varies linearly with acyl chain length in fluid phosphatidylcholine vesicles BA Lewis, DM Engelman Journal of molecular biology 166 (2), 211-217, 1983 | 984 | 1983 |
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment CJ Cheng, R Bahal, IA Babar, Z Pincus, F Barrera, C Liu, A Svoronos, ... Nature 518 (7537), 107-110, 2015 | 750 | 2015 |
Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with β-branched residues at neighboring positions A Senes, M Gerstein, DM Engelman Journal of molecular biology 296 (3), 921-936, 2000 | 739 | 2000 |
Helical membrane protein folding, stability, and evolution JL Popot, DM Engelman Annual review of biochemistry 69 (1), 881-922, 2000 | 737 | 2000 |
Sequence specificity in the dimerization of transmembrane. alpha.-helixes MA Lemmon, JM Flanagan, HR Treutlein, J Zhang, DM Engelman Biochemistry 31 (51), 12719-12725, 1992 | 650 | 1992 |
Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices. MA Lemmon, JM Flanagan, JF Hunt, BD Adair, BJ Bormann, CE Dempsey, ... Journal of Biological Chemistry 267 (11), 7683-7689, 1992 | 599 | 1992 |
OncomiR or tumor suppressor? The duplicity of microRNAs in cancer AA Svoronos, DM Engelman, FJ Slack Cancer research 76 (13), 3666-3670, 2016 | 598 | 2016 |
The Cα—H⋅⋅⋅ O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions A Senes, I Ubarretxena-Belandia, DM Engelman Proceedings of the National Academy of Sciences 98 (16), 9056-9061, 2001 | 559 | 2001 |
Path of the polypeptide in bacteriorhodopsin. DM Engelman, R Henderson, AD McLachlan, BA Wallace Proceedings of the National Academy of Sciences 77 (4), 2023-2027, 1980 | 549 | 1980 |
Modulation of the bilayer thickness of exocytic pathway membranes by membrane proteins rather than cholesterol K Mitra, I Ubarretxena-Belandia, T Taguchi, G Warren, DM Engelman Proceedings of the National Academy of Sciences 101 (12), 4083-4088, 2004 | 473 | 2004 |
Two EGF molecules contribute additively to stabilization of the EGFR dimer MA Lemmon, Z Bu, JE Ladbury, M Zhou, D Pinchasi, I Lax, DM Engelman, ... The EMBO journal 16 (2), 281-294, 1997 | 473 | 1997 |
Interhelical hydrogen bonding drives strong interactions in membrane proteins F Xiao Zhou, MJ Cocco, WP Russ, AT Brunger, DM Engelman Nature structural biology 7 (2), 154-160, 2000 | 466 | 2000 |
TOXCAT: a measure of transmembrane helix association in a biological membrane WP Russ, DM Engelman Proceedings of the National Academy of Sciences 96 (3), 863-868, 1999 | 446 | 1999 |
Polar residues drive association of polyleucine transmembrane helices FX Zhou, HJ Merianos, AT Brunger, DM Engelman Proceedings of the National Academy of Sciences 98 (5), 2250-2255, 2001 | 429 | 2001 |