Tharick A Pascoal
Tharick A Pascoal
University of Pittsburgh -
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Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts
TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ...
The Lancet Neurology 19 (5), 422-433, 2020
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology
NJ Ashton, TA Pascoal, TK Karikari, AL Benedet, J Lantero-Rodriguez, ...
Acta neuropathologica 141, 709-724, 2021
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain
KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ...
Alzheimer's research & therapy 9, 1-9, 2017
Microglial activation and tau propagate jointly across Braak stages
TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ...
Nature medicine 27 (9), 1592-1599, 2021
A multicentre validation study of the diagnostic value of plasma neurofilament light
NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ...
Nature communications 12 (1), 3400, 2021
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum
AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ...
JAMA neurology 78 (12), 1471-1483, 2021
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative
TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ...
Molecular psychiatry 26 (2), 429-442, 2021
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β
J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ...
JAMA neurology 77 (4), 470-479, 2020
18F-MK-6240 PET for early and late detection of neurofibrillary tangles
TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ...
Brain 143 (9), 2818-2830, 2020
In vivo quantification of neurofibrillary tangles with [18F]MK-6240
TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ...
Alzheimer's research & therapy 10, 1-14, 2018
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease
NM Lyra e Silva, RA Gonçalves, TA Pascoal, RAS Lima-Filho, ...
Translational psychiatry 11 (1), 251, 2021
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease
TA Pascoal, S Mathotaarachchi, S Mohades, AL Benedet, CO Chung, ...
Molecular psychiatry 22 (2), 306-311, 2017
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility
TK Karikari, NJ Ashton, G Brinkmalm, WS Brum, AL Benedet, ...
Nature Reviews Neurology 18 (7), 400-418, 2022
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals
FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ...
Alzheimer's & dementia 16 (1), 192-199, 2020
Identifying incipient dementia individuals using machine learning and amyloid imaging
S Mathotaarachchi, TA Pascoal, M Shin, AL Benedet, MS Kang, ...
Neurobiology of aging 59, 80-90, 2017
Synergistic interaction between amyloid and tau predicts the progression to dementia
TA Pascoal, S Mathotaarachchi, M Shin, AL Benedet, S Mohades, ...
Alzheimer's & Dementia 13 (6), 644-653, 2017
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging
J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ...
Nature aging 2 (6), 526-535, 2022
Validation of a regression technique for segmentation of white matter hyperintensities in Alzheimer’s disease
M Dadar, TA Pascoal, S Manitsirikul, K Misquitta, VS Fonov, MC Tartaglia, ...
IEEE transactions on medical imaging 36 (8), 1758-1768, 2017
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease
NJ Ashton, AL Benedet, TA Pascoal, TK Karikari, J Lantero-Rodriguez, ...
EBioMedicine 76, 2022
Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease
KP Ng, TA Pascoal, S Mathotaarachchi, CO Chung, AL Benedet, M Shin, ...
Neurology 88 (19), 1814-1821, 2017
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