Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ... The Lancet Neurology 19 (5), 422-433, 2020 | 719 | 2020 |
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ... Alzheimer's research & therapy 9 (1), 1-9, 2017 | 313 | 2017 |
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology NJ Ashton, TA Pascoal, TK Karikari, AL Benedet, J Lantero-Rodriguez, ... Acta neuropathologica 141, 709-724, 2021 | 303 | 2021 |
Microglial activation and tau propagate jointly across Braak stages TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ... Nature medicine 27 (9), 1592-1599, 2021 | 251 | 2021 |
A multicentre validation study of the diagnostic value of plasma neurofilament light NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ... Nature communications 12 (1), 3400, 2021 | 222 | 2021 |
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ... Molecular psychiatry 26 (2), 429-442, 2021 | 211 | 2021 |
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ... JAMA neurology 78 (12), 1471-1483, 2021 | 184 | 2021 |
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ... JAMA neurology 77 (4), 470-479, 2020 | 174 | 2020 |
18F-MK-6240 PET for early and late detection of neurofibrillary tangles TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ... Brain 143 (9), 2818-2830, 2020 | 144 | 2020 |
In vivo quantification of neurofibrillary tangles with [18F] MK-6240 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... Alzheimer's research & therapy 10 (1), 1-14, 2018 | 133 | 2018 |
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease TA Pascoal, S Mathotaarachchi, S Mohades, AL Benedet, CO Chung, ... Molecular psychiatry 22 (2), 306-311, 2017 | 128 | 2017 |
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ... Alzheimer's & dementia 16 (1), 192-199, 2020 | 113 | 2020 |
Identifying incipient dementia individuals using machine learning and amyloid imaging S Mathotaarachchi, TA Pascoal, M Shin, AL Benedet, MS Kang, ... Neurobiology of aging 59, 80-90, 2017 | 112 | 2017 |
Synergistic interaction between amyloid and tau predicts the progression to dementia TA Pascoal, S Mathotaarachchi, M Shin, AL Benedet, S Mohades, ... Alzheimer's & Dementia 13 (6), 644-653, 2017 | 105 | 2017 |
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease NM Lyra e Silva, RA Gonçalves, TA Pascoal, RAS Lima-Filho, ... Translational psychiatry 11 (1), 251, 2021 | 104 | 2021 |
Validation of a regression technique for segmentation of white matter hyperintensities in Alzheimer’s disease M Dadar, TA Pascoal, S Manitsirikul, K Misquitta, VS Fonov, MC Tartaglia, ... IEEE transactions on medical imaging 36 (8), 1758-1768, 2017 | 101 | 2017 |
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility TK Karikari, NJ Ashton, G Brinkmalm, WS Brum, AL Benedet, ... Nature Reviews Neurology 18 (7), 400-418, 2022 | 92 | 2022 |
Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease KP Ng, TA Pascoal, S Mathotaarachchi, CO Chung, AL Benedet, M Shin, ... Neurology 88 (19), 1814-1821, 2017 | 79 | 2017 |
VoxelStats: a MATLAB package for multi-modal voxel-wise brain image analysis S Mathotaarachchi, S Wang, M Shin, TA Pascoal, AL Benedet, MS Kang, ... Frontiers in neuroinformatics 10, 20, 2016 | 76 | 2016 |
Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease H Zhang, J Therriault, MS Kang, KP Ng, TA Pascoal, P Rosa-Neto, ... Alzheimer's research & therapy 10, 1-11, 2018 | 71 | 2018 |