Jens Gerwien
Jens Gerwien
Eli Lilly Immunology
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Derivatives of erythropoietin that are tissue protective but not erythropoietic
M Leist, P Ghezzi, G Grasso, R Bianchi, P Villa, M Fratelli, C Savino, ...
Science 305 (5681), 239-242, 2004
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo
S Erbayraktar, G Grasso, A Sfacteria, Q Xie, T Coleman, M Kreilgaard, ...
Proceedings of the National Academy of Sciences 100 (11), 6741-6746, 2003
Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives
P Villa, J Van Beek, AK Larsen, J Gerwien, S Christensen, A Cerami, ...
Journal of Cerebral Blood Flow & Metabolism 27 (3), 552-563, 2007
The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia‐ischemia as potently as erythropoietin
X Wang, C Zhu, X Wang, JG Gerwien, A Schrattenholz, M Sandberg, ...
Journal of neurochemistry 91 (4), 900-910, 2004
The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells
L Wang, ZG Zhang, SR Gregg, RL Zhang, Z Jiao, Y LeTourneau, X Liu, ...
Journal of Biological Chemistry 282 (44), 32462-32470, 2007
TNF-α blockade induces IL-10 expression in human CD4+ T cells
HG Evans, U Roostalu, GJ Walter, NJ Gullick, KS Frederiksen, ...
Nature communications 5 (1), 1-12, 2014
The interaction of beta 2‐microglobulin (β2m) with mouse class I major histocompatibility antigens and its ability to support peptide binding. A comparison of human and mouse β2m
LØ Pedersen, A Stryhn, TL Holtet, M Etzerodt, J Gerwien, MH Nissen, ...
European journal of immunology 25 (6), 1609-1616, 1995
High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)
A Kirkeby, L Torup, L Bochsen, M Kjalke, K Abel, K Theilgaard-Monch, ...
Journal of the International Society on Thrombosis and Haemostasis 99 (4 …, 2008
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
J Nielsen, J Pedersen, J Gerwien, K Bay, L Pedersen, M Leist, M Geist, ...
US Patent App. 10/612,665, 2004
Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
M Nielsen, MH Nissen, J Gerwien, MB Zocca, HM Rasmussen, ...
Blood, The Journal of the American Society of Hematology 99 (3), 973-977, 2002
A single-cell gene-expression profile reveals inter-cellular heterogeneity within human monocyte subsets
ST Gren, TB Rasmussen, S Janciauskiene, K Håkansson, JG Gerwien, ...
PloS one 10 (12), e0144351, 2015
Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127low Treg Cells in Patients With Chronic …
GJ Walter, V Fleskens, KS Frederiksen, M Rajasekhar, B Menon, ...
Arthritis & rheumatology 68 (1), 103-116, 2016
MHC class II ligation induces CD58 (LFA-3)-mediated adhesion in human T cells
MB Nielsen, J Gerwien, M Nielsen, C Geisler, C Röpke, A Svejgaard, ...
Experimental and clinical immunogenetics 15 (2), 61-68, 1998
The Interaction between Beta 2‐Microglobulin (ßm) and Purified Class‐I Major Histocompatibility (MHC) Antigen
LØ Pedersen, AS Hansen, AC Olsen, J Gerwien, MH Nissen, S Buus
Scandinavian journal of immunology 39 (1), 64-72, 1994
Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells
J Gerwien, M Nielsen, T Labuda, MH Nissen, A Svejgaard, C Geisler, ...
The Journal of Immunology 163 (4), 1742-1745, 1999
Activation and subsequent degradation of proacrosin is mediated by zona pellucida glycoproteins, negatively charged polysaccharides, and DNA
U Eberspaecher, J Gerwien, UF Habenicht, WD Schleuning, P Donner
Molecular reproduction and development 30 (2), 164-170, 1991
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells
E Perucha, R Melchiotti, JA Bibby, W Wu, KS Frederiksen, CA Roberts, ...
Nature communications 10 (1), 1-13, 2019
Staphylococcal enterotoxin‐A directly stimulates signal transduction and interferon‐γ production in psoriatic T‐cell lines
MB Nielsen, N Ødum, J Gerwien, A Svejgaard, K Bendtzen, S Bregentholt, ...
Tissue Antigens 52 (6), 530-538, 1998
Monomeric immunoglobulin E stabilizes FcεRIα from the human basophil cell line KU812 by protecting it from natural turnover
BM Jensen, JB Hansen, S Dissing, J Gerwien, PS Skov, LK Poulsen
Clinical & Experimental Allergy 33 (5), 655-662, 2003
Superantigens are presented by and activate thymocytes from infants
S Thulesen, A Jørgensen, J Gerwien, M Dohlsten, MH Nissen, N Ødum, ...
Experimental and clinical immunogenetics 16 (4), 226-233, 1999
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