Biochemical and Mass Spectrometric Characterization of Human N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition JM West, N Zvonok, KM Whitten, SK Vadivel, AL Bowman, A Makriyannis Public Library of Science 7 (8), e43877, 2012 | 39 | 2012 |
Mass Spectrometric Characterization of Human N-Acylethanolamine-hydrolyzing Acid Amidase JM West, N Zvonok, KM Whitten, JAT Wood, A Makriyannis Journal of proteome research 11 (2), 972-981, 2012 | 35 | 2012 |
Online/at‐line measurement, analysis and control of product titer and critical product quality attributes (CQAs) during process development L Chemmalil, T Prabhakar, J Kuang, J West, Z Tan, V Ehamparanathan, ... Biotechnology and Bioengineering 117 (12), 3757-3765, 2020 | 31 | 2020 |
Pseudo IPNs and IPNs of two porous silicas and polystyrene HL Frisch, JM West, CG Göltner, GS Attard Journal of Polymer Science Part A: Polymer Chemistry 34 (9), 1823-1826, 1996 | 26 | 1996 |
A fluorescent probe-labeled Escherichia coli aspartate transcarbamoylase that monitors the allosteric conformational state JM West, H Tsuruta, ER Kantrowitz Journal of Biological Chemistry 279 (2), 945-951, 2004 | 25 | 2004 |
Assay and inhibition of diacylglycerol lipase activity M Johnston, SR Bhatt, S Sikka, RW Mercier, JM West, A Makriyannis, ... Bioorganic & medicinal chemistry letters 22 (14), 4585-4592, 2012 | 22 | 2012 |
Characterization of the Aspartate Transcarbamoylase fromMethanococcus jannaschii ES Hack, T Vorobyova, JB Sakash, JM West, CP Macol, G Hervé, ... Journal of Biological Chemistry 275 (21), 15820-15827, 2000 | 22 | 2000 |
Time evolution of the quaternary structure of Escherichia coli aspartate transcarbamoylase upon reaction with the natural substrates and a slow, tight-binding inhibitor JM West, J Xia, H Tsuruta, W Guo, EM O'Day, ER Kantrowitz Journal of molecular biology 384 (1), 206-218, 2008 | 19 | 2008 |
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors MS Malamas, SI Farah, M Lamani, DN Pelekoudas, NT Perry, G Rajarshi, ... Bioorganic & Medicinal Chemistry 28 (1), 115195, 2020 | 18 | 2020 |
Trapping Specific Quaternary States of the Allosteric Enzyme Aspartate Transcarbamoylase in Silica Matrix Sol− Gels JM West, ER Kantrowitz Journal of the American Chemical Society 125 (33), 9924-9925, 2003 | 16 | 2003 |
Stabilization of the R allosteric structure of Escherichia coli aspartate transcarbamoylase by disulfide bond formation JM West, H Tsuruta, ER Kantrowitz Journal of Biological Chemistry 277 (49), 47300-47304, 2002 | 14 | 2002 |
The role of intersubunit interactions for the stabilization of the T state of Escherichia coli aspartate transcarbamoylase RS Chan, JB Sakash, CP Macol, JM West, H Tsuruta, ER Kantrowitz Journal of Biological Chemistry 277 (51), 49755-49760, 2002 | 13 | 2002 |
Online monitoring and control of upstream cell culture process using 1D and 2D‐LC with SegFlow interface L Chemmalil, DP Wasalathanthri, X Zhang, J Kuang, C Shao, R Barbour, ... Biotechnology and Bioengineering 118 (9), 3593-3603, 2021 | 11 | 2021 |
Vitamin B12 association with mAbs: Mechanism and potential mitigation strategies C Du, R Martin, Y Huang, A Borwankar, Z Tan, J West, N Singh, M Borys, ... Biotechnology and Bioengineering 115 (4), 900-909, 2018 | 11 | 2018 |
Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase W Guo, JM West, AS Dutton, H Tsuruta, ER Kantrowitz Proceedings of the National Academy of Sciences 109 (20), 7741-7746, 2012 | 10 | 2012 |
Process analytical technology for on‐line monitoring of quality attributes during single‐use ultrafiltration/diafiltration JM West, H Feroz, X Xu, N Puri, M Holstein, S Ghose, J Ding, ZJ Li Biotechnology and Bioengineering 118 (6), 2293-2300, 2021 | 9 | 2021 |
Paving the way for real time process monitoring in biomanufacturing DP Wasalathanthri, MS Rehmann, JM West, MC Borys, J Ding, ZJ Li Am Pharm Rev 23 (5), 54-58, 2020 | 5 | 2020 |
Design and Structure–Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors MS Malamas, S Pavlopoulos, SO Alapafuja, SI Farah, A Zvonok, ... Journal of medicinal chemistry 64 (9), 5956-5972, 2021 | 4 | 2021 |
N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) inhibitors and their use thereof M Malamas, A Makriyannis, KV Subramanian, KM Whitten, NM Zvonok, ... US Patent 10,640,494, 2020 | 4 | 2020 |
Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies S Pavlopoulos, DN Pelekoudas, O Benchama, CM Rawlins, JN Agar, ... Protein expression and purification 145, 108-117, 2018 | 4 | 2018 |