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Jay M. West
Jay M. West
Director, Repligen
Verified email at repligen.com
Title
Cited by
Cited by
Year
Biochemical and Mass Spectrometric Characterization of Human N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition
JM West, N Zvonok, KM Whitten, SK Vadivel, AL Bowman, A Makriyannis
Public Library of Science 7 (8), e43877, 2012
392012
Mass Spectrometric Characterization of Human N-Acylethanolamine-hydrolyzing Acid Amidase
JM West, N Zvonok, KM Whitten, JAT Wood, A Makriyannis
Journal of proteome research 11 (2), 972-981, 2012
352012
Online/at‐line measurement, analysis and control of product titer and critical product quality attributes (CQAs) during process development
L Chemmalil, T Prabhakar, J Kuang, J West, Z Tan, V Ehamparanathan, ...
Biotechnology and Bioengineering 117 (12), 3757-3765, 2020
312020
Pseudo IPNs and IPNs of two porous silicas and polystyrene
HL Frisch, JM West, CG Göltner, GS Attard
Journal of Polymer Science Part A: Polymer Chemistry 34 (9), 1823-1826, 1996
261996
A fluorescent probe-labeled Escherichia coli aspartate transcarbamoylase that monitors the allosteric conformational state
JM West, H Tsuruta, ER Kantrowitz
Journal of Biological Chemistry 279 (2), 945-951, 2004
252004
Assay and inhibition of diacylglycerol lipase activity
M Johnston, SR Bhatt, S Sikka, RW Mercier, JM West, A Makriyannis, ...
Bioorganic & medicinal chemistry letters 22 (14), 4585-4592, 2012
222012
Characterization of the Aspartate Transcarbamoylase fromMethanococcus jannaschii
ES Hack, T Vorobyova, JB Sakash, JM West, CP Macol, G Hervé, ...
Journal of Biological Chemistry 275 (21), 15820-15827, 2000
222000
Time evolution of the quaternary structure of Escherichia coli aspartate transcarbamoylase upon reaction with the natural substrates and a slow, tight-binding inhibitor
JM West, J Xia, H Tsuruta, W Guo, EM O'Day, ER Kantrowitz
Journal of molecular biology 384 (1), 206-218, 2008
192008
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors
MS Malamas, SI Farah, M Lamani, DN Pelekoudas, NT Perry, G Rajarshi, ...
Bioorganic & Medicinal Chemistry 28 (1), 115195, 2020
182020
Trapping Specific Quaternary States of the Allosteric Enzyme Aspartate Transcarbamoylase in Silica Matrix Sol− Gels
JM West, ER Kantrowitz
Journal of the American Chemical Society 125 (33), 9924-9925, 2003
162003
Stabilization of the R allosteric structure of Escherichia coli aspartate transcarbamoylase by disulfide bond formation
JM West, H Tsuruta, ER Kantrowitz
Journal of Biological Chemistry 277 (49), 47300-47304, 2002
142002
The role of intersubunit interactions for the stabilization of the T state of Escherichia coli aspartate transcarbamoylase
RS Chan, JB Sakash, CP Macol, JM West, H Tsuruta, ER Kantrowitz
Journal of Biological Chemistry 277 (51), 49755-49760, 2002
132002
Online monitoring and control of upstream cell culture process using 1D and 2D‐LC with SegFlow interface
L Chemmalil, DP Wasalathanthri, X Zhang, J Kuang, C Shao, R Barbour, ...
Biotechnology and Bioengineering 118 (9), 3593-3603, 2021
112021
Vitamin B12 association with mAbs: Mechanism and potential mitigation strategies
C Du, R Martin, Y Huang, A Borwankar, Z Tan, J West, N Singh, M Borys, ...
Biotechnology and Bioengineering 115 (4), 900-909, 2018
112018
Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase
W Guo, JM West, AS Dutton, H Tsuruta, ER Kantrowitz
Proceedings of the National Academy of Sciences 109 (20), 7741-7746, 2012
102012
Process analytical technology for on‐line monitoring of quality attributes during single‐use ultrafiltration/diafiltration
JM West, H Feroz, X Xu, N Puri, M Holstein, S Ghose, J Ding, ZJ Li
Biotechnology and Bioengineering 118 (6), 2293-2300, 2021
92021
Paving the way for real time process monitoring in biomanufacturing
DP Wasalathanthri, MS Rehmann, JM West, MC Borys, J Ding, ZJ Li
Am Pharm Rev 23 (5), 54-58, 2020
52020
Design and Structure–Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors
MS Malamas, S Pavlopoulos, SO Alapafuja, SI Farah, A Zvonok, ...
Journal of medicinal chemistry 64 (9), 5956-5972, 2021
42021
N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) inhibitors and their use thereof
M Malamas, A Makriyannis, KV Subramanian, KM Whitten, NM Zvonok, ...
US Patent 10,640,494, 2020
42020
Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies
S Pavlopoulos, DN Pelekoudas, O Benchama, CM Rawlins, JN Agar, ...
Protein expression and purification 145, 108-117, 2018
42018
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