| An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ... Developmental cell 31 (6), 722-733, 2014 | 1472 | 2014 |
| Cellular senescence promotes adverse effects of chemotherapy and cancer relapsecellular senescence and chemotherapy M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ... Cancer discovery 7 (2), 165-176, 2017 | 892 | 2017 |
| Direct evidence for epithelial-mesenchymal transitions in breast cancer AJ Trimboli, K Fukino, A De Bruin, G Wei, L Shen, SM Tanner, N Creasap, ... Cancer research 68 (3), 937-945, 2008 | 476 | 2008 |
| Extra-embryonic function of Rb is essential for embryonic development and viability L Wu, A de Bruin, HI Saavedra, M Starovic, A Trimboli, Y Yang, J Opavska, ... Nature 421 (6926), 942-947, 2003 | 434 | 2003 |
| MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling PA da Costa Martins, K Salic, MM Gladka, AS Armand, S Leptidis, ... Nature cell biology 12 (12), 1220-1227, 2010 | 387 | 2010 |
| Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation A de Bruin, B Maiti, L Jakoi, C Timmers, R Buerki, G Leone Journal of Biological Chemistry 278 (43), 42041-42049, 2003 | 303 | 2003 |
| In vivo biocompatibility and biodegradation of 3D-printed porous scaffolds based on a hydroxyl-functionalized poly (ε-caprolactone) H Seyednejad, D Gawlitta, RV Kuiper, A de Bruin, CF van Nostrum, ... Biomaterials 33 (17), 4309-4318, 2012 | 260 | 2012 |
| High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice RA van der Heijden, F Sheedfar, MC Morrison, PPH Hommelberg, D Kor, ... Aging (Albany NY) 7 (4), 256, 2015 | 252 | 2015 |
| Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation B Maiti, J Li, A De Bruin, F Gordon, C Timmers, R Opavsky, K Patil, J Tuttle, ... Journal of Biological Chemistry 280 (18), 18211-18220, 2005 | 251 | 2005 |
| Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development J Li, C Ran, E Li, F Gordon, G Comstock, H Siddiqui, W Cleghorn, ... Developmental cell 14 (1), 62-75, 2008 | 248 | 2008 |
| Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice WP Vermeij, MET Dollé, E Reiling, D Jaarsma, C Payan-Gomez, ... Nature 537 (7620), 427-431, 2016 | 236 | 2016 |
| A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris R Caldelari, A de Bruin, D Baumann, MM Suter, C Bierkamp, V Balmer, ... The Journal of cell biology 153 (4), 823-834, 2001 | 218 | 2001 |
| Pemphigus vulgaris identifies plakoglobin as key suppressor of c‐Myc in the skin L Williamson, NA Raess, R Caldelari, A Zakher, A de Bruin, H Posthaus, ... The EMBO journal 25 (14), 3298-3309, 2006 | 196 | 2006 |
| A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis E Brandsma, NJ Kloosterhuis, M Koster, DC Dekker, MJJ Gijbels, ... Circulation research 124 (1), 94-100, 2019 | 192 | 2019 |
| Physiological significance of polyploidization in mammalian cells SK Pandit, B Westendorp, A de Bruin Trends in cell biology 23 (11), 556-566, 2013 | 167 | 2013 |
| Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice A de Bruin, L Wu, HI Saavedra, P Wilson, Y Yang, TJ Rosol, M Weinstein, ... Proceedings of the National Academy of Sciences 100 (11), 6546-6551, 2003 | 159 | 2003 |
| E2F8 is essential for polyploidization in mammalian cells SK Pandit, B Westendorp, S Nantasanti, E Van Liere, PCJ Tooten, ... Nature cell biology 14 (11), 1181-1191, 2012 | 157 | 2012 |
| Essential role for survivin in early brain development Y Jiang, A De Bruin, H Caldas, J Fangusaro, J Hayes, EM Conway, ... Journal of Neuroscience 25 (30), 6962-6970, 2005 | 146 | 2005 |
| Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects E Sudria-Lopez, M Koppers, M de Wit, C van der Meer, HJ Westeneng, ... Acta neuropathologica 132, 145-147, 2016 | 136 | 2016 |
| The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism RI Aqeilan, MQ Hassan, A de Bruin, JP Hagan, S Volinia, T Palumbo, ... Journal of Biological Chemistry 283 (31), 21629-21639, 2008 | 135 | 2008 |
Bart van de Sluis, PhDProfessor of Molecular Genetics (Department of Pediatrics), University of GroningenVerified email at umcg.nl
