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Gian Luca Negri
Gian Luca Negri
Canada's Michael Smith Genome Sciences Centre
Verified email at bcgsc.ca
Title
Cited by
Cited by
Year
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis
AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ...
Cancer cell 27 (5), 682-697, 2015
3122015
Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
JKM Lim, A Delaidelli, SW Minaker, HF Zhang, M Colovic, H Yang, ...
Proceedings of the National Academy of Sciences 116 (19), 9433-9442, 2019
2292019
The H3K36me2 methyltransferase Nsd1 demarcates PRC2-mediated H3K27me2 and H3K27me3 domains in embryonic stem cells
G Streubel, A Watson, SG Jammula, A Scelfo, DJ Fitzpatrick, G Oliviero, ...
Molecular cell 70 (2), 371-379. e5, 2018
1562018
Quantitative genetic-interaction mapping in mammalian cells
A Roguev, D Talbot, GL Negri, M Shales, G Cagney, S Bandyopadhyay, ...
Nature methods 10 (5), 432-437, 2013
1302013
Eradication of B-ALL using chimeric antigen receptor–expressing T cells targeting the TSLPR oncoprotein
H Qin, M Cho, W Haso, L Zhang, SK Tasian, HZ Oo, GL Negri, Y Lin, ...
Blood, The Journal of the American Society of Hematology 126 (5), 629-639, 2015
1292015
Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis
AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ...
EMBO reports 20 (12), e48375, 2019
842019
Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes
K Asleh, GL Negri, SE Spencer Miko, S Colborne, CS Hughes, XQ Wang, ...
Nature Communications 13 (1), 896, 2022
622022
The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level
E Kwon, K Todorova, J Wang, R Horos, KK Lee, VA Neel, GL Negri, ...
Nature communications 9 (1), 1734, 2018
622018
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity
A Jan, B Jansonius, A Delaidelli, F Bhanshali, YA An, N Ferreira, ...
Acta neuropathologica communications 6, 1-17, 2018
592018
eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response
A Jan, B Jansonius, A Delaidelli, SP Somasekharan, F Bhanshali, ...
Acta Neuropathologica 133, 101-119, 2017
522017
Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma
HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ...
Cancer discovery 11 (11), 2884-2903, 2021
512021
Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal
G Streubel, DJ Fitzpatrick, G Oliviero, A Scelfo, B Moran, S Das, ...
The EMBO journal 36 (15), 2216-2232, 2017
462017
Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine
NM Cetinbas, J Sudderth, RC Harris, A Cebeci, GL Negri, ÖH Yılmaz, ...
Scientific reports 6 (1), 32606, 2016
442016
Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma
GL Negri, BM Grande, A Delaidelli, A El‐Naggar, D Cochrane, CC Lau, ...
The Journal of pathology 249 (3), 319-331, 2019
422019
Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation
E Gatev, AM Inkster, GL Negri, C Konwar, AA Lussier, A Skakkebaek, ...
Nucleic Acids Research 49 (16), 9097-9116, 2021
332021
HACE1 is a potential tumor suppressor in osteosarcoma
AM El-Naggar, PW Clarkson, GL Negri, B Turgu, F Zhang, MS Anglesio, ...
Cell death & disease 10 (1), 21, 2019
312019
MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation
A Delaidelli, GL Negri, A Jan, B Jansonius, A El-Naggar, JKM Lim, ...
Cell Death & Differentiation 24 (9), 1564-1576, 2017
302017
High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8
MJ Aristizabal, GL Negri, JJ Benschop, FCP Holstege, NJ Krogan, ...
PLoS genetics 9 (8), e1003758, 2013
252013
Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
KA Orlando, AK Douglas, A Abudu, Y Wang, B Tessier-Cloutier, W Su, ...
Elife 9, e59073, 2020
232020
Arginine depletion therapy with ADI-PEG20 limits tumor growth in argininosuccinate synthase–deficient ovarian cancer, including small-cell carcinoma of the ovary, hypercalcemic …
JX Ji, DR Cochrane, B Tessier-Cloutier, SY Chen, G Ho, KV Pathak, ...
Clinical Cancer Research 26 (16), 4402-4413, 2020
222020
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