| Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores X Liu, Z Zhang, J Ruan, Y Pan, VG Magupalli, H Wu, J Lieberman Nature 535 (7610), 153-158, 2016 | 2533 | 2016 |
| Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes A Lu*, VG Magupalli*, J Ruan*, Q Yin, MK Atianand, MR Vos, ... Cell 156 (6), 1193-1206 *First co-authors, 2014 | 1231 | 2014 |
| FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020 | 638 | 2020 |
| Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome H Sharif, L Wang, WL Wang, VG Magupalli, L Andreeva, Q Qiao, ... Nature 570 (7761), 338-343, 2019 | 545 | 2019 |
| Gasdermin D pore structure reveals preferential release of mature interleukin-1 S Xia, Z Zhang, VG Magupalli, JL Pablo, Y Dong, SM Vora, L Wang, ... Nature 593 (7860), 607-611, 2021 | 350 | 2021 |
| HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ... Science 369 (6510), eaas8995, 2020 | 245 | 2020 |
| SMOCs: supramolecular organizing centres that control innate immunity. JC Kagen, VG Magupalli, H Wu Nature Review Immunology 14, 821-826, 2014 | 245 | 2014 |
| Multiple RIBEYE–RIBEYE interactions create a dynamic scaffold for the formation of synaptic ribbons VG Magupalli, K Schwarz, K Alpadi, S Natarajan, GM Seigel, F Schmitz Journal of Neuroscience 28 (32), 7954-7967, 2008 | 141 | 2008 |
| NLRP3 inflammasome assembly in neutrophils is supported by PAD4 and promotes NETosis under sterile conditions P Münzer, R Negro, S Fukui, L Di Meglio, K Aymonnier, L Chu, ... Frontiers in immunology 12, 683803, 2021 | 92 | 2021 |
| Cryo-EM structures of the active NLRP3 inflammasome disc L Xiao, VG Magupalli, H Wu Nature 613 (7944), 595-600, 2023 | 80 | 2023 |
| Crystal structure of the WD40 domain dimer of LRRK2 P Zhang, Y Fan, H Ru, L Wang, VG Magupalli, SS Taylor, DR Alessi, ... Proceedings of the National Academy of Sciences 116 (5), 1579-1584, 2019 | 65 | 2019 |
| RIBEYE recruits Munc119, a mammalian ortholog of the Caenorhabditis elegans protein unc119, to synaptic ribbons of photoreceptor synapses K Alpadi, VG Magupalli, S Käppel, L Köblitz, K Schwarz, GM Seigel, ... Journal of biological chemistry 283 (39), 26461-26467, 2008 | 64 | 2008 |
| Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions A Lu, V Kabaleeswaran, T Fu, VG Magupalli, H Wu Journal of molecular biology 426 (7), 1420-1427, 2014 | 57 | 2014 |
| Ca2+-independent activation of Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2. 1 calcium channels VG Magupalli, S Mochida, J Yan, X Jiang, RE Westenbroek, AC Nairn, ... Journal of Biological Chemistry 288 (7), 4637-4648, 2013 | 41 | 2013 |
| Modulation of CaV2. 1 channels by neuronal calcium sensor-1 induces short-term synaptic facilitation J Yan, K Leal, VG Magupalli, E Nanou, GQ Martinez, T Scheuer, ... Molecular and Cellular Neuroscience 63, 124-131, 2014 | 34 | 2014 |
| Nicotinamide adenine dinucleotide-dependent binding of the neuronal Ca2+ sensor protein GCAP2 to photoreceptor synaptic ribbons JK Venkatesan, S Natarajan, K Schwarz, SI Mayer, K Alpadi, ... Journal of Neuroscience 30 (19), 6559-6576, 2010 | 30 | 2010 |
| The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses S Wahl*, VG Magupalli*, M Dembla*, R Katiyar*, K Schwarz*, L Köblitz, ... The Journal of Neuroscience 36 (8), 2473-2493 *First co-authors, 2016 | 27 | 2016 |
| Ragulator-Rag and ROS TORment gasdermin D pore formation VG Magupalli, P Fontana, H Wu Trends in immunology 42 (11), 948-950, 2021 | 8 | 2021 |
| Assembly of the Nlrp3 inflammasome regulates NET formation and is promoted by the vimentin intermediate filament cytoskeletal system P Münzer, R Negro, V Magupalli, M Kittisopikul, A Vahabikashi, SL Wong, ... Arteriosclerosis, Thrombosis, and Vascular Biology 39 (Suppl_1), A118-A118, 2019 | 3 | 2019 |
| GSDMD pore structure reveals mechanism of preferential IL-1 release S Xia, Z Zhang, VG Magupalli, JL Pablo, Y Dong, SM Vora, L Wang, ... Nature Publishing Group, 2023 | | 2023 |
Hao WuAsa and Patricia Springer Professor, Boston Children's Hospital and Harvard Medical SchoolVerified email at crystal.harvard.edu
