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Henning Kempf
Henning Kempf
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Human heart-forming organoids recapitulate early heart and foregut development
L Drakhlis, S Biswanath, CM Farr, V Lupanow, J Teske, K Ritzenhoff, ...
Nature Biotechnology 39 (6), 737-746, 2021
2382021
Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture
H Kempf, R Olmer, C Kropp, M Rückert, M Jara-Avaca, D Robles-Diaz, ...
Stem cell reports 3 (6), 1132-1146, 2014
2342014
Cardiac differentiation of human pluripotent stem cells in scalable suspension culture
H Kempf, C Kropp, R Olmer, U Martin, R Zweigerdt
Nature protocols 10 (9), 1345-1361, 2015
1622015
The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells
J Dahlmann, G Kensah, H Kempf, D Skvorc, A Gawol, DA Elliott, G Dräger, ...
Biomaterials 34 (10), 2463-2471, 2013
1492013
Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single‐Use Stirred Tank Bioreactors
C Kropp, H Kempf, C Halloin, D Robles-Diaz, A Franke, T Scheper, ...
Stem Cells Translational Medicine 5 (10), 1289-1301, 2016
1402016
Large-scale production of human pluripotent stem cell derived cardiomyocytes
H Kempf, B Andree, R Zweigerdt
Advanced drug delivery reviews 96, 18-30, 2016
1262016
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
M Ackermann, H Kempf, M Hetzel, C Hesse, AR Hashtchin, K Brinkert, ...
Nature communications 9 (1), 5088, 2018
1242018
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
H Kempf, R Olmer, A Haase, A Franke, E Bolesani, K Schwanke, ...
Nature communications 7 (1), 13602, 2016
1162016
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
C Halloin, K Schwanke, W Löbel, A Franke, M Szepes, S Biswanath, ...
Stem cell reports 13 (2), 366-379, 2019
802019
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes
N Weber, K Schwanke, S Greten, M Wendland, B Iorga, M Fischer, ...
Basic research in cardiology 111, 1-16, 2016
552016
iPSC-derived macrophages effectively treat pulmonary alveolar proteinosis in Csf2rb-deficient mice
A Mucci, E Lopez-Rodriguez, M Hetzel, S Liu, T Suzuki, C Happle, ...
Stem cell reports 11 (3), 696-710, 2018
492018
Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis
B Jaeger, JC Schupp, L Plappert, O Terwolbeck, N Artysh, G Kayser, ...
Nature communications 13 (1), 5637, 2022
472022
Expansion of functional personalized cells with specific transgene combinations
C Lipps, F Klein, T Wahlicht, V Seiffert, M Butueva, J Zauers, T Truschel, ...
Nature communications 9 (1), 994, 2018
432018
Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels
J de la Roche, P Angsutararux, H Kempf, M Janan, E Bolesani, ...
Scientific reports 9 (1), 11173, 2019
422019
Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells
H Kempf, M Lecina, S Ting, R Zweigerdt, S Oh
Stem cell research 7 (3), 198-209, 2011
392011
Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors
M Ackermann, A Rafiei Hashtchin, F Manstein, M Carvalho Oliveira, ...
Nature Protocols 17 (2), 513-539, 2022
352022
A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device
J Christoffersson, F Meier, H Kempf, K Schwanke, M Coffee, M Beilmann, ...
Bioengineering 5 (2), 36, 2018
332018
Scalable cardiac differentiation of pluripotent stem cells using specific growth factors and small molecules
H Kempf, R Zweigerdt
Springer, Berlin, Heidelberg, 2017
262017
Proteomic analysis of human pluripotent stem cell cardiomyogenesis revealed altered expression of metabolic enzymes and PDLIM5 isoforms
SA Konze, S Werneburg, A Oberbeck, R Olmer, H Kempf, M Jara-Avaca, ...
Journal of Proteome Research 16 (3), 1133-1149, 2017
252017
Fast and efficient multitransgenic modification of human pluripotent stem cells
K Schwanke, S Merkert, H Kempf, S Hartung, M Jara-Avaca, C Templin, ...
Human gene therapy methods 25 (2), 136-153, 2014
242014
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Articles 1–20