Decarboxylation mechanisms in biological system T Li, L Huo, C Pulley, A Liu Bioorganic chemistry 43, 2-14, 2012 | 126 | 2012 |
Evidence for a dual role of an active site histidine in α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase L Huo, AJ Fielding, Y Chen, T Li, H Iwaki, JP Hosler, L Chen, Y Hasegawa, ... Biochemistry 51 (29), 5811-5821, 2012 | 30 | 2012 |
Human α‐amino‐β‐carboxymuconate‐ε‐semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling L Huo, F Liu, H Iwaki, T Li, Y Hasegawa, A Liu Proteins: Structure, Function, and Bioinformatics 83 (1), 178-187, 2015 | 29 | 2015 |
Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action L Huo, I Davis, F Liu, B Andi, S Esaki, H Iwaki, Y Hasegawa, AM Orville, ... Nature communications 6 (1), 5935, 2015 | 24 | 2015 |
The power of two: arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase L Huo, I Davis, L Chen, A Liu Journal of Biological Chemistry 288 (43), 30862-30871, 2013 | 24 | 2013 |
Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in understanding … MB Shah, J Liu, L Huo, Q Zhang, MD Dearing, PR Wilderman, GD Szklarz, ... Molecular Pharmacology 89 (4), 435-445, 2016 | 17 | 2016 |
Amidohydrolase superfamily A Liu, L Huo eLS, 2014 | 14 | 2014 |
Rational Re-Engineering of the O-Dealkylation of 7-Alkoxycoumarin Derivatives by Cytochromes P450 2B from the Desert Woodrat Neotoma lepida L Huo, J Liu, MD Dearing, GD Szklarz, JR Halpert, PR Wilderman Biochemistry 56 (16), 2238-2246, 2017 | 8 | 2017 |
Discovery of 5,7-Dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-ones as Highly Selective CDK2 Inhibitors A Sokolsky, S Winterton, K Kennedy, K Drake, K Stump, L Huo, Y Lo, ... ACS Medicinal Chemistry Letters 13 (11), 1797-1804, 2022 | 5 | 2022 |
Heterolytic OO bond cleavage: Functional role of Glu113 during bis-Fe(IV) formation in MauG AL Jiafeng Geng, Lu Huo Journal of inorganic biochemistry 167, 60-67, 2017 | 5 | 2017 |
Kynurenine pathway regulation at its critical junctions with fluctuation of tryptophan A Newton, L McCann, L Huo, A Liu Metabolites 13 (4), 500, 2023 | 1 | 2023 |
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2 JR Hummel, KJ Xiao, JC Yang, LB Epling, K Mukai, Q Ye, M Xu, D Qian, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
INCA33890, a novel PD-1× TGFꞵR2 bispecific antibody conditionally antagonizes TGFꞵ signaling in primary immune cells co-expressing PD-1 LCS Wang, R Klooster, A Kulkarni, AG de Vinuesa, M Soloviev, ... Cancer Research 83 (7_Supplement), 2936-2936, 2023 | | 2023 |
Kynurenine Pathway Regulation at Its Critical Junctions with Fluctuation of Tryptophan. Metabolites 2023, 13, 500 A Newton, L McCann, L Huo, A Liu | | 2023 |
Extending the Kynurenine Pathway to an Aldehyde Disarming Enzyme: Mechanistic Study of Bacterial AMSDH and Identification of the Correct Human Enzyme I Davis, L Huo, F Liu, B Andi, S Esaki, H Iwaki, Y Hasegawa, A Orville, ... The FASEB Journal 29, 573.3, 2015 | | 2015 |
Evidence for a Dual Role of an Active Site Histidine in-Amino--carboxymuconate--semialdehyde Decarboxylase L Huo | | 2015 |
Structural and Mechanistic Studies on à-Amino?-Carboxymuconate î-Semialdehyde Decarboxylase and à-Aminomuconate î-Semialdehyde Dehydrogenase L Huo | | 2014 |
Structural and Mechanistic Studies on α-Amino β-Carboxymuconate ε-Semialdehyde Decarboxylase and α-Aminomuconate ε-Semialdehyde Dehydrogenase L Huo | | 2014 |
Volume 43, August 2012 B Davis, C Whitman, T Li, L Huo, C Pulley, A Liu, RM McCarty, ... | | 2012 |
INCA33890, a Novel TGFꞵR2× PD-1 Bispecific Antibody Conditionally Antagonizes TGFꞵ Signaling in Primary Immune Cells Co-expressing PD-1 LCS Wang, R Klooster, A Kulkarni, AG de Vinuesa, M Soloviev, ... | | |