| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 615 | 2020 |
| An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 370 | 2020 |
| Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 127 | 2021 |
| Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes AJ Pratt, DS Shin, GE Merz, RP Rambo, WA Lancaster, KN Dyer, ... Proceedings of the National Academy of Sciences 111 (43), E4568-E4576, 2014 | 85 | 2014 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... Research square, 2021 | 70 | 2021 |
| An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... BioRxiv, 2020 | 60 | 2020 |
| Copper-based pulsed dipolar ESR spectroscopy as a probe of protein conformation linked to disease states GE Merz, PP Borbat, AJ Pratt, ED Getzoff, JH Freed, BR Crane Biophysical Journal 107 (7), 1669-1674, 2014 | 41 | 2014 |
| Site-Specific Incorporation of a Cu2+ Spin Label into Proteins for Measuring Distances by Pulsed Dipolar Electron Spin Resonance Spectroscopy GE Merz, PP Borbat, AR Muok, M Srivastava, DN Bunck, JH Freed, ... The Journal of Physical Chemistry B 122 (41), 9443-9451, 2018 | 29 | 2018 |
| CK1/Doubletime activity delays transcription activation in the circadian clock D Top, JL O'Neil, GE Merz, K Dusad, BR Crane, MW Young Elife 7, e32679, 2018 | 26 | 2018 |
| Stacked binding of a PET ligand to Alzheimer’s tau paired helical filaments GE Merz, MJ Chalkley, SK Tan, E Tse, J Lee, SB Prusiner, NA Paras, ... Nature communications 14 (1), 3048, 2023 | 17 | 2023 |
| Stability of single-nucleotide bulge loops embedded in a GAAA RNA hairpin stem GFS Lim, GE Merz, MD McCann, JM Gruskiewicz, MJ Serra RNA 18 (4), 807-814, 2012 | 13 | 2012 |
| Consortium QSB, Walter P, Manglik A M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473, 2020 | 10 | 2020 |
| Aβ and tau prions causing Alzheimer’s disease C Condello, GE Merz, A Aoyagi, WF DeGrado, SB Prusiner Alzheimer’s Disease: Methods and Protocols, 293-337, 2022 | 8 | 2022 |
| The E46K mutation modulates α-synuclein prion replication in transgenic mice SAM Holec, J Lee, A Oehler, L Batia, A Wiggins-Gamble, J Lau, FK Ooi, ... PLoS Pathogens 18 (12), e1010956, 2022 | 5 | 2022 |
| Stacked binding of a small molecule PET tracer to Alzheimer’s tau paired helical filaments GE Merz, MJ Chalkley, S Tan, E Tse, J Lee, SB Prusiner, NA Paras, ... BioRxiv, 2022.09. 30.510175, 2022 | 5 | 2022 |
| Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps SG Remesh, GE Merz, AF Brilot, US Chio, AN Rizo, TH Pospiech, I Lui, ... Structure 31 (3), 253-264. e6, 2023 | 4 | 2023 |
| Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold U Ghosh, E Tse, M Shi, H Yang, F Wang, GE Merz, SB Prusiner, ... bioRxiv, 2024.04. 02.587507, 2024 | | 2024 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.(preprint) M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, GM Jang, ... | | 2021 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes (preprint) K Verba, M Gupta, C Azumaya, M Moritz, S Pourmal, A Diallo, G Merz, ... | | 2021 |
| Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor (preprint) P Roboti, KB Duah, G Zong, H Schneider, WQ Shi, S High, ID Young, ... | | 2020 |
