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Jeremy M. Sivak
Jeremy M. Sivak
University of Toronto & Krembil Research Institute, University Health Network
Verified email at uhnres.utoronto.ca - Homepage
Title
Cited by
Cited by
Year
MMPs in the eye: emerging roles for matrix metalloproteinases in ocular physiology
JM Sivak, ME Fini
Progress in retinal and eye research 21 (1), 1-14, 2002
5142002
Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B
R Mohan, J Sivak, P Ashton, LA Russo, BQ Pham, N Kasahara, ...
Journal of Biological Chemistry 275 (14), 10405-10412, 2000
3312000
The aging eye: common degenerative mechanisms between the Alzheimer's brain and retinal disease
JM Sivak
Investigative ophthalmology & visual science 54 (1), 871-880, 2013
2512013
FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation
JM Sivak, LF Petersen, E Amaya
Developmental cell 8 (5), 689-701, 2005
1702005
Pax-6 expression and activity are induced in the reepithelializing cornea and control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B
JM Sivak, R Mohan, WB Rinehart, PX Xu, RL Maas, ME Fini
Developmental biology 222 (1), 41-54, 2000
1192000
Transcription factors Pax6 and AP-2α interact to coordinate corneal epithelial repair by controlling expression of matrix metalloproteinase gelatinase B
JM Sivak, JA West-Mays, A Yee, T Williams, ME Fini
Molecular and cellular biology 24 (1), 245-257, 2004
1172004
Effect of γ-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells
IG Surgucheva, JM Sivak, ME Fini, RE Palazzo, AP Surguchov
Archives of biochemistry and biophysics 410 (1), 167-176, 2003
872003
Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury
I Livne-Bar, J Wei, HH Liu, S Alqawlaq, GJ Won, A Tuccitto, K Gronert, ...
The Journal of clinical investigation 127 (12), 4403-4414, 2017
842017
Proteomics analyses of human optic nerve head astrocytes following biomechanical strain
RS Rogers, M Dharsee, S Ackloo, JM Sivak, JG Flanagan
Molecular & Cellular Proteomics 11 (2), 2012
792012
All roads lead to glaucoma: Induced retinal injury cascades contribute to a common neurodegenerative outcome
S Alqawlaq, JG Flanagan, JM Sivak
Experimental eye research 183, 88-97, 2019
742019
ROS detoxification and proinflammatory cytokines are linked by p38 MAPK signaling in a model of mature astrocyte activation
A Nahirnyj, I Livne-Bar, X Guo, JM Sivak
PloS one 8 (12), e83049, 2013
742013
Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy
S Alqawlaq, JM Sivak, JT Huzil, MV Ivanova, JG Flanagan, MA Beazely, ...
Nanomedicine: Nanotechnology, Biology and Medicine 10 (8), 1637-1647, 2014
652014
The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury
X Guo, Q Jiang, A Tuccitto, D Chan, S Alqawlaq, GJ Won, JM Sivak
Neurobiology of disease 113, 59-69, 2018
642018
Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia
DS Wang, K Kaneshwaran, G Lei, F Mostafa, J Wang, I Lecker, ...
Anesthesiology 129 (3), 477-489, 2018
572018
PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina
X Guo, ES Dason, V Zanon-Moreno, Q Jiang, A Nahirnyj, D Chan, ...
The American journal of pathology 184 (4), 1017-1029, 2014
552014
Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis
I Livne-Bar, S Lam, D Chan, X Guo, I Askar, A Nahirnyj, JG Flanagan, ...
Cell death & disease 7 (9), e2386-e2386, 2016
492016
Positive influence of AP-2α transcription factor on cadherin gene expression and differentiation of the ocular surface
JA West-Mays, JM Sivak, SS Papagiotas, J Kim, T Nottoli, T Williams, ...
Differentiation 71 (3), 206-216, 2003
412003
Lamina cribrosa pore shape and size as predictors of neural tissue mechanical insult
AP Voorhees, NJ Jan, ME Austin, JG Flanagan, JM Sivak, RA Bilonick, ...
Investigative ophthalmology & visual science 58 (12), 5336-5346, 2017
382017
Aqueous humour concentrations of TGF‐β, PLGF and FGF‐1 and total retinal blood flow in patients with early non‐proliferative diabetic retinopathy
LA Khuu, F Tayyari, JM Sivak, JG Flanagan, S Singer, MH Brent, D Huang, ...
Acta ophthalmologica 95 (3), e206-e211, 2017
372017
The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR …
CM Adams, K Anderson, G Artman Iii, JC Bizec, R Cepeda, J Elliott, ...
Journal of medicinal chemistry 61 (4), 1622-1635, 2018
302018
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