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Mo Chen
Mo Chen
Verified email at mail.tsinghua.edu.cn
Title
Cited by
Cited by
Year
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
M Chen, JL Manley
Nature reviews Molecular cell biology 10 (11), 741-754, 2009
14632009
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
CJ David, M Chen, M Assanah, P Canoll, JL Manley
Nature 463 (7279), 364-368, 2010
12132010
TGF-β tumor suppression through a lethal EMT
CJ David, YH Huang, M Chen, J Su, Y Zou, N Bardeesy, ...
Cell 164 (5), 1015-1030, 2016
5792016
Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA
M Chen, J Zhang, JL Manley
Cancer research 70 (22), 8977-8980, 2010
2402010
Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins
M Chen, CJ David, JL Manley
Nature structural & molecular biology 19 (3), 346-354, 2012
1212012
Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator
Y Feng, M Chen, JL Manley
Nature structural & molecular biology 15 (10), 1040-1048, 2008
1122008
MLL-AF9–and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C
N Zhu, M Chen, R Eng, J DeJong, AU Sinha, NF Rahnamay, R Koche, ...
The Journal of clinical investigation 126 (3), 997-1011, 2016
1032016
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors
M Chen, N Zhu, X Liu, B Laurent, Z Tang, R Eng, Y Shi, SA Armstrong, ...
Genes & development 29 (20), 2123-2139, 2015
932015
Mutant Kras co-opts a proto-oncogenic enhancer network in inflammation-induced metaplastic progenitor cells to initiate pancreatic cancer
Y Li, Y He, J Peng, Z Su, Z Li, B Zhang, J Ma, M Zhuo, D Zou, X Liu, X Liu, ...
Nature Cancer 2 (1), 49-65, 2021
592021
Tumor-derived Jagged1 promotes cancer progression through immune evasion
J Meng, Y Jiang, S Zhao, Y Tao, T Zhang, X Wang, Y Zhang, K Sun, ...
Cell Reports 38 (10), 2022
202022
The PAF1 complex promotes 3′ processing of pervasive transcripts
X Liu, Z Guo, J Han, B Peng, B Zhang, H Li, X Hu, CJ David, M Chen
Cell reports 38 (11), 2022
192022
Tumor metabolism: hnRNP proteins get in on the act
M Chen, CJ David, JL Manley
Cell Cycle 9 (10), 1863-1864, 2010
162010
p300 通过 homeobox 结构域增强 Nanog 的转录激活活性
郭允倩, 陈默, 马天骅, 裴端卿
中国生物工程杂志 29 (10), 1-5, 2009
72009
LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t (8; 21) AML
Q Chen, MA Cevher, Q Jiang, S Wang, X Sun, RG Roeder, M Chen
Proceedings of the National Academy of Sciences 119 (42), e2213718119, 2022
42022
Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
X Liu, X Liu, Y Du, D Zou, C Tian, Y Li, X Lan, CJ David, Q Sun, M Chen
Cell Reports 42 (8), 2023
12023
CircR-looping the leukemic translocations: The cause of MLL translocations explained
M Chen
Molecular Cell 83 (13), 2164-2166, 2023
12023
Defining pervasive transcription units using chromatin RNA-sequencing data
Z Guo, X Liu, M Chen
STAR protocols 3 (2), 101442, 2022
12022
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