Peter Dirks
Peter Dirks
Professor of Surgery
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
Identification of human brain tumour initiating cells
SK Singh, C Hawkins, ID Clarke, JA Squire, J Bayani, T Hide, ...
nature 432 (7015), 396-401, 2004
79522004
Identification of a cancer stem cell in human brain tumors
SK Singh, ID Clarke, M Terasaki, VE Bonn, C Hawkins, J Squire, PB Dirks
Cancer research 63 (18), 5821-5828, 2003
60422003
Cancer stem cells: an evolving concept
LV Nguyen, R Vanner, P Dirks, CJ Eaves
Nature Reviews Cancer 12 (2), 133-143, 2012
11012012
Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
BBS Zhou, H Zhang, M Damelin, KG Geles, JC Grindley, PB Dirks
Nature reviews Drug discovery 8 (10), 806-823, 2009
9302009
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
SM Pollard, K Yoshikawa, ID Clarke, D Danovi, S Stricker, R Russell, ...
Cell stem cell 4 (6), 568-580, 2009
9112009
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
9002015
Cancer stem cells in nervous system tumors
SK Singh, ID Clarke, T Hide, PB Dirks
Oncogene 23 (43), 7267-7273, 2004
8632004
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49-56, 2012
7012012
Hypothermia therapy after traumatic brain injury in children
JS Hutchison, RE Ward, J Lacroix, PC Hébert, MA Barnes, DJ Bohn, ...
New England Journal of Medicine 358 (23), 2447-2456, 2008
6282008
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
E Bouffet, V Larouche, BB Campbell, D Merico, R De Borja, M Aronson, ...
Journal of clinical oncology 34 (19), 2206-2211, 2016
5082016
Intertumoral heterogeneity within medulloblastoma subgroups
FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ...
Cancer cell 31 (6), 737-754. e6, 2017
4862017
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
4752014
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
3712017
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
M Meyer, J Reimand, X Lan, R Head, X Zhu, M Kushida, J Bayani, ...
Proceedings of the National Academy of Sciences 112 (3), 851-856, 2015
2722015
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ...
Nature genetics 47 (3), 257-262, 2015
2632015
Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus
AV Kulkarni, J Drake J, CL Mallucci, S Sgouros, J Roth, S Constantini, ...
The Journal of pediatrics 155 (2), 254-9, 2009
2522009
Divergent clonal selection dominates medulloblastoma at recurrence
AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ...
Nature 529 (7586), 351-357, 2016
2452016
Frequent amplification of a chr19q13. 41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors
M Li, KF Lee, Y Lu, I Clarke, D Shih, C Eberhart, VP Collins, T Van Meter, ...
Cancer cell 16 (6), 533-546, 2009
2172009
BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma
C Hawkins, E Walker, N Mohamed, C Zhang, K Jacob, M Shirinian, ...
Clinical Cancer Research 17 (14), 4790-4798, 2011
2112011
Quiescent Sox2+ cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma
RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee, ...
Cancer cell 26 (1), 33-47, 2014
2092014
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