| Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction S Oddo, A Caccamo, JD Shepherd, MP Murphy, TE Golde, R Kayed, ... Neuron 39 (3), 409-421, 2003 | 4799 | 2003 |
| The cell biology of synaptic plasticity: AMPA receptor trafficking JD Shepherd, RL Huganir Annu. Rev. Cell Dev. Biol. 23, 613-643, 2007 | 1151 | 2007 |
| Arc/Arg3. 1 interacts with the endocytic machinery to regulate AMPA receptor trafficking S Chowdhury, JD Shepherd, H Okuno, G Lyford, RS Petralia, N Plath, ... Neuron 52 (3), 445-459, 2006 | 921 | 2006 |
| Arc/Arg3. 1 mediates homeostatic synaptic scaling of AMPA receptors JD Shepherd, G Rumbaugh, J Wu, S Chowdhury, N Plath, D Kuhl, ... Neuron 52 (3), 475-484, 2006 | 876 | 2006 |
| Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3. 1 essential for mGluR-LTD S Park, JM Park, S Kim, JA Kim, JD Shepherd, CL Smith-Hicks, ... Neuron 59 (1), 70-83, 2008 | 599 | 2008 |
| The neuronal gene arc encodes a repurposed retrotransposon gag protein that mediates intercellular RNA transfer ED Pastuzyn, CE Day, RB Kearns, M Kyrke-Smith, AV Taibi, J McCormick, ... Cell 172 (1), 275-288. e18, 2018 | 547 | 2018 |
| New views of Arc, a master regulator of synaptic plasticity JD Shepherd, MF Bear Nature neuroscience 14 (3), 279-284, 2011 | 525 | 2011 |
| Arc/Arg3. 1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation J Wu, RS Petralia, H Kurushima, H Patel, M Jung, L Volk, S Chowdhury, ... Cell 147 (3), 615-628, 2011 | 221 | 2011 |
| Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation CL McCurry, JD Shepherd, D Tropea, KH Wang, MF Bear, M Sur Nature neuroscience 13 (4), 450-457, 2010 | 184 | 2010 |
| Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse JM Gee, NA Smith, FR Fernandez, MN Economo, D Brunert, M Rothermel, ... Neuron 83 (5), 1058-1072, 2014 | 137 | 2014 |
| Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression JA Beagan, ED Pastuzyn, LR Fernandez, MH Guo, K Feng, KR Titus, ... Nature neuroscience 23 (6), 707-717, 2020 | 122 | 2020 |
| The temporal dynamics of arc expression regulate cognitive flexibility MJ Wall, DR Collins, SL Chery, ZD Allen, ED Pastuzyn, AJ George, ... Neuron 98 (6), 1124-1132. e7, 2018 | 91 | 2018 |
| The role of ionotropic glutamate receptors in childhood neurodevelopmental disorders: autism spectrum disorders and fragile x syndrome G Uzunova, E Hollander, J Shepherd Current neuropharmacology 12 (1), 71-98, 2014 | 86 | 2014 |
| SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells C Smith-Hicks, B Xiao, R Deng, Y Ji, X Zhao, JD Shepherd, G Posern, ... Nature neuroscience 13 (9), 1082-1089, 2010 | 77 | 2010 |
| Memory, plasticity and sleep-A role for calcium permeable AMPA receptors? JD Shepherd Frontiers in molecular neuroscience 5, 15048, 2012 | 62 | 2012 |
| Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins S Erlendsson, DR Morado, HB Cullen, C Feschotte, JD Shepherd, ... Nature neuroscience 23 (2), 172-175, 2020 | 56 | 2020 |
| The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling DG Brown, R Soto, S Yandamuri, C Stone, L Dickey, JC Gomes-Neto, ... Elife 8, e47117, 2019 | 50 | 2019 |
| Activity-dependent Arc expression and homeostatic synaptic plasticity are altered in neurons from a mouse model of Angelman syndrome ED Pastuzyn, JD Shepherd Frontiers in molecular neuroscience 10, 234, 2017 | 47 | 2017 |
| Arc restores juvenile plasticity in adult mouse visual cortex KR Jenks, T Kim, ED Pastuzyn, H Okuno, AV Taibi, H Bito, MF Bear, ... Proceedings of the National Academy of Sciences 114 (34), 9182-9187, 2017 | 45 | 2017 |
| Deep-brain imaging via epi-fluorescence computational cannula microscopy G Kim, N Nagarajan, E Pastuzyn, K Jenks, M Capecchi, J Shepherd, ... Scientific reports 7 (1), 44791, 2017 | 40 | 2017 |
Richard L HuganirProfessor of Neuroscience, Johns Hopkins University School of MedicineVerified email at jhmi.edu
