Rebecca S Shapiro
Rebecca S Shapiro
Assistant Professor, University of Guelph
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Regulatory circuitry governing fungal development, drug resistance, and disease
RS Shapiro, N Robbins, LE Cowen
Microbiology and molecular biology reviews 75 (2), 213-267, 2011
Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling
RS Shapiro, P Uppuluri, AK Zaas, C Collins, H Senn, JR Perfect, ...
Current Biology 19 (8), 621-629, 2009
Global gene deletion analysis exploring yeast filamentous growth
O Ryan, RS Shapiro, CF Kurat, D Mayhew, A Baryshnikova, B Chin, ...
Science 337 (6100), 1353-1356, 2012
A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans
RS Shapiro, A Chavez, CBM Porter, M Hamblin, CS Kaas, JE DiCarlo, ...
Nature Microbiology 3 (1), 73-82, 2018
Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing
RS Shapiro, LE Cowen
mBio 3 (5), 2012
Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry
S Diezmann, M Michaut, RS Shapiro, GD Bader, LE Cowen
PLoS Genetics 8 (3), e1002562, 2012
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro
Annals of the New York Academy of Sciences, 2018
The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance
RS Shapiro, AK Zaas, M Betancourt-Quiroz, JR Perfect, LE Cowen
PLOS ONE 7 (9), e44734, 2012
Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise
RS Shapiro, A Sellam, F Tebbji, M Whiteway, A Nantel, LE Cowen
Current Biology 22 (6), 461-470, 2012
CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms
RS Shapiro, A Chavez, JJ Collins
Nature Reviews Microbiology 16 (6), 333-339, 2018
A role for the bacterial GATC methylome in antibiotic stress survival
NR Cohen, CA Ross, S Jain, RS Shapiro, A Gutierrez, P Belenky, H Li, ...
Nature Genetics, 2016
Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans
H Senn, RS Shapiro, LE Cowen
Molecular Biology of the Cell 23 (2), 268-283, 2012
Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans
RS Shapiro, LE Cowen
Virulence 1 (1), 45-48, 2010
Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens
J Sharma, S Rosiana, I Razzaq, RS Shapiro
Journal of Fungi 5 (1), 17, 2019
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space
AO Veri, Z Miao, RS Shapiro, F Tebbji, TR O’Meara, SH Kim, J Colazo, ...
PLoS Genetics 14 (3), e1007270, 2018
Antimicrobial-induced DNA damage and genomic instability in microbial pathogens
RS Shapiro
PLoS Pathogens 11 (3), e1004678, 2015
Metabolism‐induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells
GJ Thomson, C Hernon, N Austriaco, RS Shapiro, P Belenky, RJ Bennett
The EMBO journal 38 (19), e101597, 2019
A CRISPR interference platform for efficient genetic repression in Candida albicans
L Wensing, J Sharma, D Uthayakumar, Y Proteau, A Chavez, RS Shapiro
mSphere 4 (1), 2019
Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis
RS Shapiro, LE Cowen
Virulence 3 (4), 400-404, 2012
Precise Cas9 targeting enables genomic mutation prevention
A Chavez, BW Pruitt, M Tuttle, RS Shapiro, RJ Cecchi, J Winston, ...
Proceedings of the National Academy of Sciences 115 (14), 3669-3673, 2018
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