Prem Ponka
Prem Ponka
Professor of Physiology, McGill University, Lady Davis Institute, Montreal, QC, Canada
Verified email at mcgill.ca - Homepage
TitleCited byYear
The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells
DR Richardson, P Ponka
Biochimica Et Biophysica Acta (BBA)-Reviews on Biomembranes 1331 (1), 1-40, 1997
7131997
Function and regulation of transferrin and ferritin.
P Ponka, C Beaumont, DR Richardson
Seminars in hematology 35 (1), 35-54, 1998
6161998
Cell biology of heme
P Ponka
The American journal of the medical sciences 318 (4), 241-256, 1999
5871999
Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells
P Ponka
Blood 89 (1), 1-25, 1997
5851997
The transferrin receptor: role in health and disease
P Ponka, CN Lok
The international journal of biochemistry & cell biology 31 (10), 1111-1137, 1999
5801999
Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron
F Canonne-Hergaux, S Gruenheid, P Ponka, P Gros
Blood 93 (12), 4406-4417, 1999
4961999
Iron overload in human disease
RE Fleming, P Ponka
New England Journal of Medicine 366 (4), 348-359, 2012
4392012
A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics
M Whitnall, J Howard, P Ponka, DR Richardson
Proceedings of the National Academy of Sciences 103 (40), 14901-14906, 2006
4202006
Identification of a hypoxia response element in the transferrin receptor gene
CN Lok, P Ponka
Journal of Biological Chemistry 274 (34), 24147-24152, 1999
3741999
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
DR Richardson, DJR Lane, EM Becker, MLH Huang, M Whitnall, ...
Proceedings of the National Academy of Sciences 107 (24), 10775-10782, 2010
3432010
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents
DR Richardson, EH Tran, P Ponka
Blood 86 (11), 4295-4306, 1995
3381995
NEW INSIGHTS INTO ERYTHROPOIESIS: The Roles of Folate, Vitamin B12, and Iron
MJ Koury, P Ponka
Annu. Rev. Nutr. 24, 105-131, 2004
3242004
Iron trafficking in the mitochondrion: novel pathways revealed by disease
I Napier, P Ponka, DR Richardson
Blood 105 (5), 1867-1874, 2005
2952005
Cellular iron metabolism
P Ponka
Kidney international 55, S2-S11, 1999
2771999
Mobilization of iron from reticulocytes. Identification of pyridoxal isonicotinoyl hydrazone as a new iron chelating agent.
P Ponka, J Borova, J Neuwirt, O Fuchs
FEBS letters 97 (2), 317, 1979
2311979
Direct interorganellar transfer of iron from endosome to mitochondrion
AD Sheftel, AS Zhang, C Brown, OS Shirihai, P Ponka
Blood 110 (1), 125-132, 2007
2132007
Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development
D Yoon, YD Pastore, V Divoky, E Liu, AE Mlodnicka, K Rainey, P Ponka, ...
Journal of Biological Chemistry 281 (35), 25703-25711, 2006
2102006
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload
MP Mims, Y Guan, D Pospisilova, M Priwitzerova, K Indrak, P Ponka, ...
Blood 105 (3), 1337-1342, 2005
2102005
A study of intracellular iron metabolism using pyridoxal isonicotinoyl hydrazone and other synthetic chelating agents
P Poňka, J Borová, J Neuwirt, O Fuchs, E Nečas
Biochimica et Biophysica Acta (BBA)-General Subjects 586 (2), 278-297, 1979
2051979
Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes
DB Lovejoy, PJ Jansson, UT Brunk, J Wong, P Ponka, DR Richardson
Cancer research 71 (17), 5871-5880, 2011
1852011
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