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Takuya Toyonaga
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Assessing synaptic density in Alzheimer disease with synaptic vesicle glycoprotein 2A positron emission tomographic imaging
MK Chen, AP Mecca, M Naganawa, SJ Finnema, T Toyonaga, S Lin, ...
JAMA neurology 75 (10), 1215-1224, 2018
3612018
In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET
AP Mecca, MK Chen, RS O'Dell, M Naganawa, T Toyonaga, TA Godek, ...
Alzheimer's & Dementia 16 (7), 974-982, 2020
1892020
Synaptic changes in Parkinson disease assessed with in vivo imaging
D Matuskey, S Tinaz, KC Wilcox, M Naganawa, T Toyonaga, M Dias, ...
Annals of neurology 87 (3), 329-338, 2020
1332020
Assessment of a white matter reference region for 11C-UCB-J PET quantification
S Rossano, T Toyonaga, SJ Finnema, M Naganawa, Y Lu, N Nabulsi, ...
Journal of Cerebral Blood Flow & Metabolism 40 (9), 1890-1901, 2020
912020
Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [11C]UCB-J
RS O’Dell, AP Mecca, MK Chen, M Naganawa, T Toyonaga, Y Lu, ...
Alzheimer's Research & Therapy 13, 1-12, 2021
702021
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J
AP Mecca, RS O'Dell, ES Sharp, ER Banks, HH Bartlett, W Zhao, S Lipior, ...
Alzheimer's & Dementia 18 (12), 2527-2536, 2022
682022
Comparison of [11C]UCB-J and [18F]FDG PET in Alzheimer’s disease: A tracer kinetic modeling study
MK Chen, AP Mecca, M Naganawa, JD Gallezot, T Toyonaga, J Mondal, ...
Journal of Cerebral Blood Flow & Metabolism 41 (9), 2395-2409, 2021
652021
In vivo synaptic density imaging with 11C-UCB-J detects treatment effects of saracatinib in a mouse model of Alzheimer disease
T Toyonaga, LM Smith, SJ Finnema, JD Gallezot, M Naganawa, J Bini, ...
Journal of Nuclear Medicine 60 (12), 1780-1786, 2019
652019
In vivo evidence of lower synaptic vesicle density in schizophrenia
R Radhakrishnan, PD Skosnik, M Ranganathan, M Naganawa, ...
Molecular Psychiatry 26 (12), 7690-7698, 2021
602021
Reduced synaptic vesicle protein 2A binding in temporal lobe epilepsy: A [11C]UCB‐J positron emission tomography study
SJ Finnema, T Toyonaga, K Detyniecki, MK Chen, M Dias, Q Wang, ...
Epilepsia 61 (10), 2183-2193, 2020
572020
Hypoxic glucose metabolism in glioblastoma as a potential prognostic factor
T Toyonaga, S Yamaguchi, K Hirata, K Kobayashi, O Manabe, ...
European journal of nuclear medicine and molecular imaging 44, 611-619, 2017
532017
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q
J Spurrier, LS Nicholson, XT Fang, AJ Stoner, T Toyonaga, D Holden, ...
Science translational medicine 14 (647), eabi8593, 2022
442022
Data-driven voluntary body motion detection and non-rigid event-by-event correction for static and dynamic PET
Y Lu, JD Gallezot, M Naganawa, S Ren, K Fontaine, J Wu, JA Onofrey, ...
Physics in Medicine & Biology 64 (6), 065002, 2019
422019
Synthesis and Preclinical Evaluation of an 18F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [18F]SynVesT-2
Z Cai, S Li, W Zhang, R Pracitto, X Wu, E Baum, SJ Finnema, D Holden, ...
ACS chemical neuroscience 11 (4), 592-603, 2020
392020
Data-driven motion detection and event-by-event correction for brain PET: Comparison with Vicra
Y Lu, M Naganawa, T Toyonaga, JD Gallezot, K Fontaine, S Ren, ...
Journal of Nuclear Medicine 61 (9), 1397-1403, 2020
362020
18F-fluoromisonidazole positron emission tomography can predict pathological necrosis of brain tumors
T Toyonaga, K Hirata, S Yamaguchi, KC Hatanaka, S Yuzawa, O Manabe, ...
European journal of nuclear medicine and molecular imaging 43, 1469-1476, 2016
362016
Imaging of synaptic density in neurodegenerative disorders
RE Carson, M Naganawa, T Toyonaga, S Koohsari, Y Yang, MK Chen, ...
Journal of Nuclear Medicine 63 (Supplement 1), 60S-67S, 2022
352022
A novel loss function incorporating imaging acquisition physics for PET attenuation map generation using deep learning
L Shi, JA Onofrey, EM Revilla, T Toyonaga, D Menard, J Ankrah, ...
Medical Image Computing and Computer Assisted Intervention–MICCAI 2019: 22nd …, 2019
332019
Change in 18F-Fluoromisonidazole PET Is an Early Predictor of the Prognosis in the Patients with Recurrent High-Grade Glioma Receiving Bevacizumab Treatment
S Yamaguchi, K Hirata, T Toyonaga, K Kobayashi, Y Ishi, H Motegi, ...
PLoS One 11 (12), e0167917, 2016
292016
Biodistribution and radiation dosimetry of the novel hypoxia PET probe [18F]DiFA and comparison with [18F]FMISO
S Watanabe, T Shiga, K Hirata, K Magota, S Okamoto, T Toyonaga, ...
EJNMMI research 9, 1-11, 2019
282019
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