Follow
Craig R. MacNair
Craig R. MacNair
Postdoctoral Researcher, Genentech
Verified email at mcmaster.ca
Title
Cited by
Cited by
Year
A deep learning approach to antibiotic discovery
JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ...
Cell 180 (4), 688-702. e13, 2020
16102020
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance
JM Stokes, CR MacNair, B Ilyas, S French, JP Côté, C Bouwman, ...
Nature microbiology 2 (5), 1-8, 2017
2982017
Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics
CR MacNair, JM Stokes, LA Carfrae, AA Fiebig-Comyn, BK Coombes, ...
Nature communications 9 (1), 458, 2018
2592018
Uncovering the Hidden Antibiotic Potential of Cannabis
ED Farha, M. A., El-Halfawy, O. M., Gale, R. T., MacNair, C. R., Carfrae, L ...
ACS infectious diseases 6 (3), 338-346, 2020
1142020
Outer membrane disruption overcomes intrinsic, acquired, and spontaneous antibiotic resistance
CR MacNair, ED Brown
MBio 11 (5), 10.1128/mbio. 01615-20, 2020
652020
The genome-wide interaction network of nutrient stress genes in Escherichia coli
JP Côté, S French, SS Gehrke, CR MacNair, CS Mangat, A Bharat, ...
MBio 7 (6), 10.1128/mbio. 01714-16, 2016
52*2016
Creative targeting of the Gram‐negative outer membrane in antibiotic discovery
CR MacNair, CN Tsai, ED Brown
Annals of the New York Academy of Sciences 1459 (1), 69-85, 2020
342020
Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens
LA Carfrae, CR MacNair, CM Brown, CN Tsai, BS Weber, S Zlitni, VN Rao, ...
Nature Microbiology 5 (1), 93-101, 2020
342020
Targeting two-component systems uncovers a small-molecule inhibitor of Salmonella virulence
CN Tsai, CR MacNair, MPT Cao, JN Perry, J Magolan, ED Brown, ...
Cell chemical biology 27 (7), 793-805. e7, 2020
332020
Overcoming acquired and native macrolide resistance with bicarbonate
MA Farha, CR MacNair, LA Carfrae, SS El Zahed, MJ Ellis, HKR Tran, ...
ACS Infectious Diseases 6 (10), 2709-2718, 2020
192020
Preclinical development of pentamidine analogs identifies a potent and nontoxic antibiotic adjuvant
CR MacNair, MA Farha, MH Serrano-Wu, KK Lee, B Hubbard, JP Côté, ...
ACS Infectious Diseases 8 (4), 768-777, 2022
162022
Management of phytophthora blight (Phytophthora capsici) on vegetables in Ontario: some greenhouse and field aspects
RF Cerkauskas, G Ferguson, C MacNair
Canadian journal of plant pathology 37 (3), 285-304, 2015
162015
A genetic platform to investigate the functions of bacterial drug efflux pumps
T Teelucksingh, LK Thompson, S Zhu, NM Kuehfuss, JA Goetz, SE Gilbert, ...
Nature Chemical Biology 18 (12), 1399-1409, 2022
142022
Exploiting the sensitivity of nutrient transporter deletion strains in discovery of natural product antimetabolites
SS Gehrke, G Kumar, NA Yokubynas, JP Côté, W Wang, S French, ...
ACS Infectious Diseases 3 (12), 955-965, 2017
132017
Inhibiting fatty acid synthesis overcomes colistin resistance
LA Carfrae, K Rachwalski, S French, R Gordzevich, L Seidel, CN Tsai, ...
Nature Microbiology 8 (6), 1026-1038, 2023
122023
Antibacterial activity of metergoline analogues: revisiting the ergot alkaloid scaffold for antibiotic discovery
JW Johnson, MJ Ellis, ZA Piquette, C MacNair, L Carfrae, T Bhando, ...
ACS Medicinal Chemistry Letters 13 (2), 284-291, 2022
112022
Bicarbonate as a potentiator for antimicrobial agents
E Brown, M Farha, C MacNair, J Stokes
US Patent 10,940,163, 2021
112021
A cell-based approach to characterize antimicrobial compounds through kinetic dose response
CR MacNair, JM Stokes, S French, CL Myers, KR Iyer, ED Brown
Bioorganic & Medicinal Chemistry 24 (24), 6315-6319, 2016
92016
The role of bacterial membrane vesicles in antibiotic resistance
CR MacNair, MW Tan
Annals of the New York Academy of Sciences 1519 (1), 63-73, 2023
82023
Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium
MJ Ellis, LA Carfrae, CR Macnair, RS Trussler, ED Brown, DB Haniford
RNA biology 15 (2), 176-181, 2018
82018
The system can't perform the operation now. Try again later.
Articles 1–20