| Epigallocatechin gallate (EGCG) and rutin suppress the glucotoxicity through activating IRS2 and AMPK signaling in rat pancreatic β cells EP Cai, JK Lin Journal of agricultural and food chemistry 57 (20), 9817-9827, 2009 | 196 | 2009 |
| Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth D Zhu, Y Zhang, PPL Lam, S Dolai, Y Liu, EP Cai, D Choi, SA Schroer, ... Cell metabolism 16 (2), 238-249, 2012 | 92 | 2012 |
| DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice SY Shi, SY Lu, T Sivasubramaniyam, XS Revelo, EP Cai, CT Luk, ... Nature communications 6 (1), 7415, 2015 | 90 | 2015 |
| In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking EP Cai, M Casimir, SA Schroer, CT Luk, SY Shi, D Choi, XQ Dai, ... Diabetes 61 (7), 1708-1718, 2012 | 81 | 2012 |
| Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance SY Shi, RG Martin, RE Duncan, D Choi, SY Lu, SA Schroer, EP Cai, ... Journal of Biological Chemistry 287 (13), 10277-10288, 2012 | 74 | 2012 |
| Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes EP Cai, Y Ishikawa, W Zhang, NC Leite, J Li, S Hou, B Kiaf, ... Nature metabolism 2 (9), 934-945, 2020 | 62 | 2020 |
| FAK signalling controls insulin sensitivity through regulation of adipocyte survival CT Luk, SY Shi, EP Cai, T Sivasubramaniyam, M Krishnamurthy, JJ Brunt, ... Nature communications 8 (1), 14360, 2017 | 61 | 2017 |
| Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy KJA Cox AR, Barrandon O, Cai EP, Rios JS, Chavez J, Bonnyman CW, Lam CJ, Yi ... PLoS One 11 (7), e0159276, 2016 | 56 | 2016 |
| Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice D Choi, EP Cai, SA Schroer, L Wang, M Woo Laboratory investigation 91 (4), 527-538, 2011 | 30 | 2011 |
| Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α-and β-cell fate EP Cai, X Wu, SA Schroer, AJ Elia, MC Nostro, E Zacksenhaus, M Woo Proceedings of the National Academy of Sciences 110 (36), 14723-14728, 2013 | 23 | 2013 |
| Janus Kinase 2 (JAK2) dissociates hepatosteatosis from hepatocellular carcinoma in mice SY Shi, CT Luk, SA Schroer, MJ Kim, DW Dodington, ... Journal of Biological Chemistry 292 (9), 3789-3799, 2017 | 21 | 2017 |
| Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions L Wang, CT Luk, SA Schroer, AM Smith, X Li, EP Cai, H Gaisano, ... Diabetologia 57, 1889-1898, 2014 | 21 | 2014 |
| In vivo knockdown of adipocyte erythropoietin receptor does not alter glucose or energy homeostasis CT Luk, SY Shi, D Choi, EP Cai, SA Schroer, M Woo Endocrinology 154 (10), 3652-3659, 2013 | 20 | 2013 |
| PTEN deletion in pancreatic α-cells protects against high-fat diet–induced hyperglucagonemia and insulin resistance L Wang, CT Luk, EP Cai, SA Schroer, EM Allister, SY Shi, MB Wheeler, ... Diabetes 64 (1), 147-157, 2015 | 19 | 2015 |
| Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action EP Cai, CT Luk, X Wu, SA Schroer, SY Shi, T Sivasubramaniyam, JJ Brunt, ... Diabetologia 57, 2555-2565, 2014 | 13 | 2014 |
| Redundant role of the cytochrome c-mediated intrinsic apoptotic pathway in pancreatic b-cells D Choi, SA Schroer, SY Lu, EP Cai, Z Hao, M Woo J Endocrinol 210, 285-292, 2011 | 11 | 2011 |
| RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity CJ Contreras, N Mukherjee, RCS Branco, L Lin, MF Hogan, EP Cai, ... Molecular Metabolism 65, 101582, 2022 | 10 | 2022 |
| The redundant role of JAK2 in regulating pancreatic β-cell mass D Choi, EP Cai, M Woo Islets 3 (6), 389-392, 2011 | 8 | 2011 |
| Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis JJ Brunt, SY Shi, SA Schroer, T Sivasubramaniyam, EP Cai, M Woo Islets 6 (5-6), e1006075, 2014 | 5 | 2014 |
| Timing is everything: Rb’s choice in islet-cell fate EP Cai, X Wu, E Zacksenhaus, M Woo Cell Cycle 13 (6), 873-874, 2014 | 4 | 2014 |
Minna WooAssociate Professor of Medicine, University of TorontoVerified email at uhnresearch.ca
