| Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2 (+)-ATPase. OLE Thastrup, PJ Cullen, BK Drøbak, MR Hanley, AP Dawson Proceedings of the National Academy of Sciences 87 (7), 2466-2470, 1990 | 3801 | 1990 |
| Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells: evidence that an intracellular calcium pool, and not an inositol phosphate, regulates … H Takemura, AR Hughes, O Thastrup, JW Putney Journal of Biological Chemistry 264 (21), 12266-12271, 1989 | 978 | 1989 |
| Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage O Thastrup, AP Dawson, O Scharff, B Foder, PJ Cullen, BK Drøbak, ... Agents and actions 27, 17-23, 1989 | 681* | 1989 |
| [Leu31, Pro34] neuropeptide Y: a specific Y1 receptor agonist. J Fuhlendorff, U Gether, L Aakerlund, N Langeland-Johansen, ... Proceedings of the National Academy of Sciences 87 (1), 182-186, 1990 | 470 | 1990 |
| A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells TR Jackson, SI Patterson, O Thastrup, MR Hanley Biochemical Journal 253 (1), 81-86, 1988 | 391 | 1988 |
| Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD (P) H responses in pancreatic islet β cells GH Patterson, SM Knobel, P Arkhammar, O Thastrup, DW Piston Proceedings of the National Academy of Sciences 97 (10), 5203-5207, 2000 | 337 | 2000 |
| Role of Ca2+-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2+-ATPase inhibitor, thapsigargin O Thastrup Agents and actions 29, 8-15, 1990 | 316 | 1990 |
| Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells CY Kwan, H Takemura, JF Obie, O Thastrup, JW Putney Jr American Journal of Physiology-Cell Physiology 258 (6), C1006-C1015, 1990 | 236 | 1990 |
| How do inositol phosphates regulate calcium signaling? JW Putney Jr, H Takemura, AR Hughes, DA Horstman, O Thastrup The FASEB journal 3 (8), 1899-1905, 1989 | 211 | 1989 |
| Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor LK Poulsen, N Jacobsen, BB Sørensen, NCH Bergenhem, JD Kelly, ... Journal of Biological Chemistry 273 (11), 6228-6232, 1998 | 205 | 1998 |
| Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase L Aakerlund, U Gether, J Fuhlendorff, TW Schwartz, O Thastrup FEBS letters 260 (1), 73-78, 1990 | 187 | 1990 |
| Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles B Papp, A Enyedi, T Kovacs, B Sarkadi, F Wuytack, O Thastrup, G Gardos, ... Journal of Biological Chemistry 266 (22), 14593-14596, 1991 | 164 | 1991 |
| The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism … O Thastrup, B Foder, O Scharff Biochemical and biophysical research communications 142 (3), 654-660, 1987 | 163 | 1987 |
| Jr Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates … H Takemura, AR Hughes, O Thastrup, JW Putney Jr J Biol Chem 264 (21), 12266-12271, 1989 | 160 | 1989 |
| The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. H Ali, SB Christensen, JC Foreman, FL Pearce, W Piotrowski, O Thastrup British journal of pharmacology 85 (3), 705, 1985 | 132 | 1985 |
| Method of detecting biologically active substances by using green fluorescent protein O Thastrup, LK Poulsen US Patent 5,958,713, 1999 | 122 | 1999 |
| Fluorescent proteins O Thastrup, S Tullin, LK Poulsen, SP Bjørn US Patent 6,172,188, 2001 | 117 | 2001 |
| The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations O Thastrup, H Linnebjerg, PJ Bjerrum, JB Knudsen, SB Christensen Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 927 (1), 65-73, 1987 | 112 | 1987 |
| Method and apparatus for high density format screening for bioactive molecules BR Terry, KM Scudder, POG Arkhammer, O Thastrup US Patent 6,790,652, 2004 | 107 | 2004 |
| Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain A Verma, DJ Hirsch, MR Hanley, O Thastrup, SB Christensen, SH Snyder Biochemical and biophysical research communications 172 (2), 811-816, 1990 | 97 | 1990 |
Søren Brøgger ChristensenUniversity of CopenhagenVerified email at sund.ku.dk
