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Shenghong Ma
Shenghong Ma
Verified email at ucsd.edu
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Year
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
M Xiao, H Yang, W Xu, S Ma, H Lin, H Zhu, L Liu, Y Liu, C Yang, Y Xu, ...
Genes & development 26 (12), 1326-1338, 2012
10952012
The Hippo pathway: biology and pathophysiology
S Ma, Z Meng, R Chen, KL Guan
Annual review of biochemistry 88, 577-604, 2019
8272019
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
H Yang, Y Liu, F Bai, JY Zhang, SH Ma, J Liu, ZD Xu, HG Zhu, ZQ Ling, ...
Oncogene 32 (5), 663-669, 2013
6452013
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation
Y Wang, M Xiao, X Chen, L Chen, Y Xu, L Lv, P Wang, H Yang, S Ma, ...
Molecular cell 57 (4), 662-673, 2015
3052015
The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell
SW Plouffe, KC Lin, JL Moore, FE Tan, S Ma, Z Ye, Y Qiu, B Ren, KL Guan
Journal of Biological Chemistry 293 (28), 11230-11240, 2018
2192018
Oncometabolite D-2-hydroxyglutarate inhibits ALKBH DNA repair enzymes and sensitizes IDH mutant cells to alkylating agents
P Wang, J Wu, S Ma, L Zhang, J Yao, KA Hoadley, MD Wilkerson, ...
Cell reports 13 (11), 2353-2361, 2015
2042015
Dual-phase stimulated Raman scattering microscopy for real-time two-color imaging
R He, Y Xu, L Zhang, S Ma, X Wang, D Ye, M Ji
Optica 4 (1), 44-47, 2017
1042017
R-2-hydroxyglutarate as the key effector of IDH mutations promoting oncogenesis
D Ye, S Ma, Y Xiong, KL Guan
Cancer cell 23 (3), 274-276, 2013
1012013
STRIPAK integrates upstream signals to initiate the Hippo kinase cascade
R Chen, R Xie, Z Meng, S Ma, KL Guan
Nature cell biology 21 (12), 1565-1577, 2019
942019
Oncogenic R132 IDH1 mutations limit NADPH for de novo lipogenesis through (D) 2-hydroxyglutarate production in fibrosarcoma cells
MG Badur, T Muthusamy, SJ Parker, S Ma, SK McBrayer, T Cordes, ...
Cell reports 25 (4), 1018-1026. e4, 2018
802018
D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth
S Ma, B Jiang, W Deng, ZK Gu, FZ Wu, T Li, Y Xia, H Yang, D Ye, Y Xiong, ...
Oncotarget 6 (11), 8606, 2015
642015
Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer
S Ma, T Tang, G Probst, A Konradi, C Jin, F Li, JS Gutkind, XD Fu, ...
Nature communications 13 (1), 1061, 2022
592022
Hippo signalling maintains ER expression and ER+ breast cancer growth
S Ma, Z Wu, F Yang, J Zhang, RL Johnson, MG Rosenfeld, KL Guan
Nature 591 (7848), E1-E10, 2021
402021
L2hgdh deficiency accumulates l-2-hydroxyglutarate with progressive leukoencephalopathy and neurodegeneration
S Ma, R Sun, B Jiang, J Gao, W Deng, P Liu, R He, J Cui, M Ji, W Yi, ...
Molecular and cellular biology, 2017
372017
Polycystic kidney disease: a Hippo connection
S Ma, KL Guan
Genes & development 32 (11-12), 737-739, 2018
222018
YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis
Z Wu, J Su, F Li, T Chen, J Mayner, A Engler, S Ma, Q Li, KL Guan
Nature Communications 14 (1), 5916, 2023
32023
D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH
S Ma, B Jiang, W Deng
Oncotarget, 6 (11), 2015
2015
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Articles 1–17