Transposable elements drive widespread expression of oncogenes in human cancers HS Jang, NM Shah, AY Du, ZZ Dailey, EC Pehrsson, PM Godoy, D Zhang, ... Nature genetics 51 (4), 611-617, 2019 | 287 | 2019 |
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 275 | 2017 |
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation J Zhou, RL Sears, X Xing, B Zhang, D Li, NB Rockweiler, HS Jang, ... BMC genomics 18, 1-17, 2017 | 99 | 2017 |
Co-opted transposons help perpetuate conserved higher-order chromosomal structures MNK Choudhary, RZ Friedman, JT Wang, HS Jang, X Zhuo, T Wang Genome biology 21, 1-14, 2020 | 88 | 2020 |
Evolution of epigenetic regulation in vertebrate genomes RF Lowdon, HS Jang, T Wang Trends in Genetics 32 (5), 269-283, 2016 | 88 | 2016 |
Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility HJ Lee, Y Hou, Y Chen, ZZ Dailey, A Riddihough, HS Jang, T Wang, ... Genome biology 21, 1-17, 2020 | 50 | 2020 |
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements NM Shah, HJ Jang, Y Liang, JH Maeng, SC Tzeng, A Wu, NL Basri, X Qu, ... Nature Genetics 55 (4), 631-639, 2023 | 43 | 2023 |
Transcription Start Site Evolution in Drosophila BJ Main, AD Smith, H Jang, SV Nuzhdin Molecular biology and evolution 30 (8), 1966-1974, 2013 | 32 | 2013 |
Genome-wide characterization of genetic variation in the unicellular, green alga Chlamydomonas reinhardtii H Jang, IM Ehrenreich PLoS One 7 (7), e41307, 2012 | 25 | 2012 |
A phase II trial of guadecitabine plus atezolizumab in metastatic urothelial carcinoma progressing after initial immune checkpoint inhibitor therapy HJ Jang, G Hostetter, AW Macfarlane, Z Madaj, EA Ross, T Hinoue, ... Clinical Cancer Research 29 (11), 2052-2065, 2023 | 12 | 2023 |
Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish HS Jang, Y Chen, J Ge, AN Wilkening, Y Hou, HJ Lee, YR Choi, ... Genome biology 22, 1-18, 2021 | 12 | 2021 |
DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods Y He, HS Jang, X Xing, D Li, MJ Vasek, JD Dougherty, T Wang Science Advances 6 (27), eaba0521, 2020 | 11 | 2020 |
Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis JA Karlow, S Devarakonda, X Xing, HS Jang, R Govindan, M Watson, ... Cancer research 82 (15), 2692-2703, 2022 | 7 | 2022 |
RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer HT Li, HJ Jang, K Rohena-Rivera, M Liu, H Gujar, J Kulchycki, S Zhao, ... Cell reports 42 (1), 2023 | 6 | 2023 |
Safety, outcomes, and T-cell characteristics in patients with relapsed or refractory MDS or CMML treated with atezolizumab in combination with guadecitabine CL O'Connell, MR Baer, AD Ørskov, SK Saini, VH Duong, P Kropf, ... Clinical Cancer Research 28 (24), 5306-5316, 2022 | 4 | 2022 |
Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidome JH Maeng, HJ Jang, AY Du, SC Tzeng, T Wang Genome Research 33 (12), 2143-2155, 2023 | 1 | 2023 |
Capture Methylation-Sensitive Restriction Enzyme Sequencing (Capture MRE-Seq) for Methylation Analysis of Highly Degraded DNA Samples X Xing, JA Karlow, D Li, HS Jang, HJ Lee, T Wang Clinical Applications of Nucleic Acid Amplification, 73-89, 2023 | | 2023 |
Loss of SETD2 sensitizes kidney cancer cells to DNA methylation inhibitors by inducing viral mimicry and RNA mis-splicing HT Li, HS Jang, K Rohena-Rivera, H Gujar, M Liu, J Kulchycki, X Zhou, ... Cancer Research 82 (12_Supplement), 3618-3618, 2022 | | 2022 |
A Phase II trial of guadecitabine (G) plus atezolizumab (A) in patients with metastatic urothelial carcinoma (UC) progressing after initial checkpoint inhibitor therapy. ER Plimack, K Campbell, JPJ Issa, NM Hahn, DI Quinn, HS Jang, ... CANCER RESEARCH 81 (13), 2021 | | 2021 |
Transposable elements are an abundant and pan-cancer source of shared tumor-specific antigens and membrane targets NM Shah, HS Jang, JH Maeng, SC Tzeng, A Wu, C Fan, NL Basri, B Katz, ... Cancer Research 81 (13_Supplement), 2225-2225, 2021 | | 2021 |