| Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond XR Xu, D Zhang, BE Oswald, N Carrim, X Wang, Y Hou, Q Zhang, ... Critical reviews in clinical laboratory sciences 53 (6), 409-430, 2016 | 337 | 2016 |
| Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents XR Xu, GM Yousef, H Ni Blood, The Journal of the American Society of Hematology 131 (16), 1777-1789, 2018 | 279 | 2018 |
| Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies XR Xu, N Carrim, MAD Neves, T McKeown, TW Stratton, RMP Coelho, ... Thrombosis journal 14, 37-46, 2016 | 188 | 2016 |
| Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis A Cameron-Vendrig, A Reheman, MA Siraj, XR Xu, Y Wang, X Lei, ... Diabetes 65 (6), 1714-1723, 2016 | 106 | 2016 |
| Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis XR Xu, Y Wang, R Adili, L Ju, CM Spring, JW Jin, H Yang, MAD Neves, ... Nature communications 9 (1), 3608, 2018 | 90 | 2018 |
| The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy G Zhu, Q Zhang, EC Reddy, N Carrim, Y Chen, XR Xu, M Xu, Y Wang, ... Blood, The Journal of the American Society of Hematology 129 (13), 1840-1854, 2017 | 66 | 2017 |
| Platelets, immune-mediated thrombocytopenias, and fetal hemorrhage XR Xu, RC Gallant, H Ni Thrombosis Research 141, S76-S79, 2016 | 33 | 2016 |
| Coenzyme Q10 upregulates platelet cAMP/PKA pathway and attenuates integrin αIIbβ3 signaling and thrombus growth F Ya, XR Xu, Y Shi, RC Gallant, F Song, X Zuo, Y Zhao, Z Tian, C Zhang, ... Molecular nutrition & food research 63 (23), 1900662, 2019 | 30 | 2019 |
| In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα BX Li, X Dai, XR Xu, R Adili, MAD Neves, X Lei, C Shen, G Zhu, Y Wang, ... Scientific reports 11 (1), 11663, 2021 | 28 | 2021 |
| Targeting activated platelets and fibrinolysis: hitting two birds with one stone A Reheman, X Xu, EC Reddy, H Ni Circulation research 114 (7), 1070-1073, 2014 | 24 | 2014 |
| Coenzyme Q10 attenuates platelet integrin αIIbβ3 signaling and platelet hyper-reactivity in ApoE-deficient mice F Ya, XR Xu, Z Tian, RC Gallant, F Song, Y Shi, Y Wu, J Wan, Y Zhao, ... Food & function 11 (1), 139-152, 2020 | 13 | 2020 |
| Identification and characterization of an alternative splice variant of Mpl with a high affinity for TPO and its activation of ERK1/2 signaling Q Wang, R Sun, L Wu, J Huang, P Wang, H Yuan, F Qiu, X Xu, D Wu, ... The international journal of biochemistry & cell biology 45 (12), 2852-2863, 2013 | 12 | 2013 |
| c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance F Li, Y Xiong, M Yang, P Chen, J Zhang, Q Wang, M Xu, Y Wang, Z He, ... Cell Death & Disease 13 (10), 869, 2022 | 4 | 2022 |
| Apolipoprotein Α-IV is a novel ligand of platelet αIIbβ3 integrin and an endogenous thrombosis inhibitor: measurement of single-molecular interactions by biomembrane force probe X Xu, CM Spring, L Ju, Y Wang, A Reheman, H Yang, JW Jin, X Lei, ... Blood 124 (21), 92, 2014 | 3 | 2014 |
| Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-thrombotic therapy N Carrim, G Zhu, EC Reddy, M Xu, X Xu, Y Wang, Y Hou, L Ma, C Lavalle, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 60-61, 2015 | 2 | 2015 |
| Coenzyme Q10 Attenuates Platelet Integrin αIIbβ3 Outside-in Signaling through Targeting cAMP/PKA Pathway and Inhibits Atherosclerosis Y Yang, XR Xu, H Ni, L Ma, W Ling, F Ya Blood 132, 2423, 2018 | | 2018 |
| Apolipoprotein A-IV is an Endogenous Protective Factor for Atherothrombosis XR Xu, Y Wang, R Adili, L Ju, CM Spring, JW Jin, H Yang, P Chen, ... Atherosclerosis Supplements 32, 30-31, 2018 | | 2018 |
| Magnesium Lithospermate B Inhibits Blood Coagulation and Platelet Aggregation: Novel Mechanism of a Traditional Drug for Cardiovascular Diseases Y Wang, D Zhang, X Xu, X Lei, Y Wang, L Xuan, J Ding, H Ni Arteriosclerosis, Thrombosis, and Vascular Biology 36 (suppl_1), A140-A140, 2016 | | 2016 |
| Apolipoprotein A-IV: Novel αIIbβ3 Integrin Ligand and Endogenous Thrombotic Inhibitor XR Xu University of Toronto (Canada), 2015 | | 2015 |
| PSI domain of beta 3 integrin contains endogenous thiol isomerase function that can be inhibited by a PDI inhibitor bacitracin and anti-PSI monoclonal antibodies EC Reddy, G Zhu, P Chen, A Reheman, X Lei, X Xu, T Petruzziello, M Rui, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12, 71-71, 2014 | | 2014 |
Heyu NiScientist, Canadian Blood Services & St. Michael's Hospital; Professor, University of TorontoVerified email at smh.ca
