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Zachery R. Gregorich
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Large cardiac muscle patches engineered from human induced-pluripotent stem cell–derived cardiac cells improve recovery from myocardial infarction in swine
L Gao, ZR Gregorich, W Zhu, S Mattapally, Y Oduk, X Lou, R Kannappan, ...
Circulation 137 (16), 1712-1730, 2018
3922018
Top‐down proteomics in health and disease: Challenges and opportunities
ZR Gregorich, Y Ge
Proteomics 14 (10), 1195-1210, 2014
2372014
MASH suite pro: a comprehensive software tool for top-down proteomics
W Cai, H Guner, ZR Gregorich, AJ Chen, S Ayaz-Guner, Y Peng, ...
Molecular & Cellular Proteomics 15 (2), 703-714, 2016
1392016
Top-down proteomics reveals concerted reductions in myofilament and Z-disc protein phosphorylation after acute myocardial infarction
Y Peng, ZR Gregorich, SG Valeja, H Zhang, W Cai, YC Chen, H Guner, ...
Molecular & Cellular Proteomics 13 (10), 2752-2764, 2014
1162014
Top-down proteomics: technology advancements and applications to heart diseases
W Cai, TM Tucholski, ZR Gregorich, Y Ge
Expert review of proteomics 13 (8), 717-730, 2016
1072016
Proteomics in heart failure: top-down or bottom-up?
ZR Gregorich, YH Chang, Y Ge
Pflügers Archiv-European Journal of Physiology 466, 1199-1209, 2014
1042014
MASH Suite: a user-friendly and versatile software interface for high-resolution mass spectrometry data interpretation and visualization
H Guner, PL Close, W Cai, H Zhang, Y Peng, ZR Gregorich, Y Ge
Journal of The American Society for Mass Spectrometry 25 (3), 464-470, 2014
942014
Three dimensional liquid chromatography coupling ion exchange chromatography/hydrophobic interaction chromatography/reverse phase chromatography for effective protein …
SG Valeja, L Xiu, ZR Gregorich, H Guner, S Jin, Y Ge
Analytical chemistry 87 (10), 5363-5371, 2015
862015
New mass-spectrometry-compatible degradable surfactant for tissue proteomics
YH Chang, ZR Gregorich, AJ Chen, L Hwang, H Guner, D Yu, J Zhang, ...
Journal of proteome research 14 (3), 1587-1599, 2015
862015
Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics
T Tucholski, W Cai, ZR Gregorich, EF Bayne, SD Mitchell, SJ McIlwain, ...
Proceedings of the National Academy of Sciences 117 (40), 24691-24700, 2020
762020
Specific enrichment of phosphoproteins using functionalized multivalent nanoparticles
L Hwang, S Ayaz-Guner, ZR Gregorich, W Cai, SG Valeja, S Jin, Y Ge
Journal of the American Chemical Society 137 (7), 2432-2435, 2015
702015
An unbiased proteomics method to assess the maturation of human pluripotent stem cell–derived cardiomyocytes
W Cai, J Zhang, WJ de Lange, ZR Gregorich, H Karp, ET Farrell, ...
Circulation research 125 (11), 936-953, 2019
682019
In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry
Y Peng, D Yu, Z Gregorich, X Chen, AM Beyer, DD Gutterman, Y Ge
Journal of muscle research and cell motility 34, 199-210, 2013
542013
Top-down targeted proteomics reveals decrease in myosin regulatory light-chain phosphorylation that contributes to sarcopenic muscle dysfunction
ZR Gregorich, Y Peng, W Cai, Y Jin, L Wei, AJ Chen, SH McKiernan, ...
Journal of proteome research 15 (8), 2706-2716, 2016
532016
Novel sarcopenia-related alterations in sarcomeric protein post-translational modifications (PTMs) in skeletal muscles identified by top-down proteomics
L Wei, ZR Gregorich, Z Lin, W Cai, Y Jin, SH McKiernan, S McIlwain, ...
Molecular & Cellular Proteomics 17 (1), 134-145, 2018
372018
Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry
ZR Gregorich, W Cai, Z Lin, AJ Chen, Y Peng, T Kohmoto, Y Ge
Journal of molecular and cellular cardiology 107, 13-21, 2017
362017
Comprehensive assessment of chamber-specific and transmural heterogeneity in myofilament protein phosphorylation by top-down mass spectrometry
ZR Gregorich, Y Peng, NM Lane, JJ Wolff, S Wang, W Guo, H Guner, ...
Journal of molecular and cellular cardiology 87, 102-112, 2015
312015
Impact of phosphorylation on the mass spectrometry quantification of intact phosphoproteins
Z Wu, TN Tiambeng, W Cai, B Chen, Z Lin, ZR Gregorich, Y Ge
Analytical chemistry 90 (8), 4935-4939, 2018
262018
Quantitative proteomics and immunohistochemistry reveal insights into cellular and molecular processes in the infarct border zone one month after myocardial infarction
L Yang, ZR Gregorich, W Cai, P Zhang, B Young, Y Gu, J Zhang, Y Ge
Journal of proteome research 16 (5), 2101-2112, 2017
262017
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms
JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ...
Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023
232023
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Articles 1–20