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Kristin J Hope
Kristin J Hope
Senior Scientist, University Health Network
Verified email at uhnresearch.ca - Homepage
Title
Cited by
Cited by
Year
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
L Jin, KJ Hope, Q Zhai, F Smadja-Joffe, JE Dick
Nature medicine 12 (10), 1167-1174, 2006
15342006
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
KJ Hope, L Jin, JE Dick
Nature immunology 5 (7), 738-743, 2004
12942004
Modeling the initiation and progression of human acute leukemia in mice
F Barabé, JA Kennedy, KJ Hope, JE Dick
Science 316 (5824), 600-604, 2007
4532007
Concepts of human leukemic development
JK Warner, JCY Wang, KJ Hope, L Jin, JE Dick
Oncogene 23 (43), 7164-7177, 2004
3092004
An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity
KJ Hope, S Cellot, SB Ting, T MacRae, N Mayotte, NN Iscove, ...
Cell stem cell 7 (1), 101-113, 2010
1662010
Human acute myeloid leukemia stem cells
KJ Hope, L Jin, JE Dick
Archives of medical research 34 (6), 507-514, 2003
1382003
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells
S Rentas, NT Holzapfel, MS Belew, GA Pratt, V Voisin, BT Wilhelm, ...
Nature 532 (7600), 508-511, 2016
1352016
The rational development of CD133-targeting immunotherapies for glioblastoma
P Vora, C Venugopal, SK Salim, N Tatari, D Bakhshinyan, M Singh, ...
Cell Stem Cell 26 (6), 832-844. e6, 2020
1312020
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid …
P Chen, J Wang, K Hope, L Jin, J Dick, R Cameron, J Brandwein, ...
Journal of Nuclear Medicine 47 (5), 827-836, 2006
1222006
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid …
P Chen, J Wang, K Hope, L Jin, J Dick, R Cameron, J Brandwein, ...
Journal of Nuclear Medicine 47 (5), 827-836, 2006
1222006
Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2
SB Ting, E Deneault, K Hope, S Cellot, J Chagraoui, N Mayotte, JF Dorn, ...
Blood, The Journal of the American Society of Hematology 119 (11), 2510-2522, 2012
1062012
A role for GPx3 in activity of normal and leukemia stem cells
O Herault, KJ Hope, E Deneault, N Mayotte, J Chagraoui, BT Wilhelm, ...
Journal of Experimental Medicine 209 (5), 895-901, 2012
1042012
OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome
M Uddin, BK Unda, V Kwan, NT Holzapfel, SH White, L Chalil, ...
The American Journal of Human Genetics 102 (2), 278-295, 2018
892018
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity
S Cellot, KJ Hope, J Chagraoui, M Sauvageau, E Deneault, T MacRae, ...
Blood, The Journal of the American Society of Hematology 122 (9), 1545-1555, 2013
702013
RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity
BT Wilhelm, M Briau, P Austin, A Faubert, G Boucher, P Chagnon, K Hope, ...
Blood, The Journal of the American Society of Hematology 117 (2), e27-e38, 2011
702011
Very long chain fatty acid metabolism is required in acute myeloid leukemia
M Tcheng, A Roma, N Ahmed, RW Smith, P Jayanth, MD Minden, ...
Blood, The Journal of the American Society of Hematology 137 (25), 3518-3532, 2021
652021
Clonal interrogation of stem cells
K Hope, M Bhatia
Nature Methods 8 (Suppl 4), S36-S40, 2011
532011
Aberrant clonal hematopoiesis following lentiviral vector transduction of HSPCs in a rhesus macaque
DA Espinoza, X Fan, D Yang, SF Cordes, LL Truitt, KR Calvo, IM Yabe, ...
Molecular Therapy 27 (6), 1074-1086, 2019
322019
DIXDC1 phosphorylation and control of dendritic morphology are impaired by rare genetic variants
V Kwan, DP Meka, SH White, CL Hung, NT Holzapfel, S Walker, ...
Cell reports 17 (7), 1892-1904, 2016
292016
PLAG1 and USF2 co-regulate expression of Musashi-2 in human hematopoietic stem and progenitor cells
MS Belew, S Bhatia, AK Chahi, S Rentas, JS Draper, KJ Hope
Stem cell reports 10 (4), 1384-1397, 2018
282018
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