Kristin J Hope
Kristin J Hope
Assistant Professor, McMaster University
Verified email at mcmaster.ca - Homepage
TitleCited byYear
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
L Jin, KJ Hope, Q Zhai, F Smadja-Joffe, JE Dick
Nature medicine 12 (10), 1167-1174, 2006
12492006
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
KJ Hope, L Jin, JE Dick
Nature immunology 5 (7), 738-743, 2004
10432004
Modeling the initiation and progression of human acute leukemia in mice
F Barabé, JA Kennedy, KJ Hope, JE Dick
Science 316 (5824), 600-604, 2007
3632007
Concepts of human leukemic development
JK Warner, JCY Wang, KJ Hope, L Jin, JE Dick
Oncogene 23 (43), 7164-7177, 2004
2752004
An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity
KJ Hope, S Cellot, SB Ting, T MacRae, N Mayotte, NN Iscove, ...
Cell stem cell 7 (1), 101-113, 2010
1292010
Human acute myeloid leukemia stem cells
KJ Hope, L Jin, JE Dick
Archives of medical research 34 (6), 507-514, 2003
1202003
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid …
P Chen, J Wang, K Hope, L Jin, J Dick, R Cameron, J Brandwein, ...
Journal of Nuclear Medicine 47 (5), 827-836, 2006
1022006
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid …
P Chen, J Wang, K Hope, L Jin, J Dick, R Cameron, J Brandwein, ...
Journal of Nuclear Medicine 47 (5), 827-836, 2006
1022006
Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2
SB Ting, E Deneault, K Hope, S Cellot, J Chagraoui, N Mayotte, JF Dorn, ...
Blood, The Journal of the American Society of Hematology 119 (11), 2510-2522, 2012
692012
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells
S Rentas, NT Holzapfel, MS Belew, GA Pratt, V Voisin, BT Wilhelm, ...
Nature 532 (7600), 508-511, 2016
632016
RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity
BT Wilhelm, M Briau, P Austin, A Faubert, G Boucher, P Chagnon, K Hope, ...
Blood, The Journal of the American Society of Hematology 117 (2), e27-e38, 2011
572011
A role for GPx3 in activity of normal and leukemia stem cells
O Herault, KJ Hope, E Deneault, N Mayotte, J Chagraoui, BT Wilhelm, ...
Journal of Experimental Medicine 209 (5), 895-901, 2012
532012
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity
S Cellot, KJ Hope, J Chagraoui, M Sauvageau, E Deneault, T MacRae, ...
Blood, The Journal of the American Society of Hematology 122 (9), 1545-1555, 2013
522013
Clonal interrogation of stem cells
K Hope, M Bhatia
Nature Methods 8 (4), S36-S40, 2011
462011
OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome
M Uddin, BK Unda, V Kwan, NT Holzapfel, SH White, L Chalil, ...
The American Journal of Human Genetics 102 (2), 278-295, 2018
242018
Roles for MSI2 and PROX1 in hematopoietic stem cell activity
KJ Hope, G Sauvageau
Current opinion in hematology 18 (4), 203-207, 2011
182011
DIXDC1 phosphorylation and control of dendritic morphology are impaired by rare genetic variants
V Kwan, DP Meka, SH White, CL Hung, NT Holzapfel, S Walker, ...
Cell reports 17 (7), 1892-1904, 2016
162016
Producing megakaryocytes from a human peripheral blood source
N Ivetic, I Nazi, N Karim, R Clare, JW Smith, JC Moore, KJ Hope, ...
Transfusion 56 (5), 1066-1074, 2016
112016
PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells
MS Belew, S Bhatia, AK Chahi, S Rentas, JS Draper, KJ Hope
Stem cell reports 10 (4), 1384-1397, 2018
72018
MicroRNA Expression Profiling in Sorted AML Subpopulations: A Possible Role for miR-155/BIC in Stem Cell Maintenance and Leukemogenesis.
ER Lechman, KJ Hope, FJ Suarez Saiz, K Takenaka, CM Croce, ...
Blood, The Journal of the American Society of Hematology 106 (11), 466-466, 2005
72005
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Articles 1–20