| DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 593 (7860), 586-590, 2021 | 862 | 2021 |
| The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression G Lei, Y Zhang, P Koppula, X Liu, J Zhang, SH Lin, JA Ajani, Q Xiao, ... Cell research 30 (2), 146-162, 2020 | 726 | 2020 |
| BAP1 links metabolic regulation of ferroptosis to tumour suppression Y Zhang, J Shi, X Liu, L Feng, Z Gong, P Koppula, K Sirohi, X Li, Y Wei, ... Nature cell biology 20 (10), 1181-1192, 2018 | 653 | 2018 |
| Energy-stress-mediated AMPK activation inhibits ferroptosis H Lee, F Zandkarimi, Y Zhang, JK Meena, J Kim, L Zhuang, S Tyagi, L Ma, ... Nature cell biology 22 (2), 225-234, 2020 | 651 | 2020 |
| Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer P Koppula, Y Zhang, L Zhuang, B Gan Cancer communications 38, 1-13, 2018 | 567 | 2018 |
| mTORC1 couples cyst (e) ine availability with GPX4 protein synthesis and ferroptosis regulation Y Zhang, RV Swanda, L Nie, X Liu, C Wang, H Lee, G Lei, C Mao, ... Nature communications 12 (1), 1-14, 2021 | 369 | 2021 |
| Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ... Nature cell biology 25 (3), 404-414, 2023 | 305 | 2023 |
| Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer X Liu, K Olszewski, Y Zhang, EW Lim, J Shi, X Zhang, J Zhang, H Lee, ... Nature cell biology 22 (4), 476-486, 2020 | 271 | 2020 |
| The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate P Koppula, Y Zhang, J Shi, W Li, B Gan Journal of Biological Chemistry 292 (34), 14240-14249, 2017 | 211 | 2017 |
| Roles of Rap1 signaling in tumor cell migration and invasion YL Zhang, RC Wang, K Cheng, BZ Ring, L Su Cancer biology & medicine 14 (1), 90, 2017 | 197 | 2017 |
| Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development ZD Xiao, L Han, H Lee, L Zhuang, Y Zhang, J Baddour, D Nagrath, ... Nature communications 8 (1), 783, 2017 | 179 | 2017 |
| A targetable CoQ-FSP1 axis drives ferroptosis-and radiation-resistance in KEAP1 inactive lung cancers P Koppula, G Lei, Y Zhang, Y Yan, C Mao, L Kondiparthi, J Shi, X Liu, ... Nature communications 13 (1), 2206, 2022 | 168 | 2022 |
| PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer T Hong, G Lei, X Chen, H Li, X Zhang, N Wu, Y Zhao, Y Zhang, J Wang Redox biology 42, 101928, 2021 | 165 | 2021 |
| A targetable LIFR− NF-κB− LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis F Yao, Y Deng, Y Zhao, Y Mei, Y Zhang, X Liu, C Martinez, X Su, ... Nature communications 12 (1), 7333, 2021 | 131 | 2021 |
| Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity G Lei, Y Zhang, T Hong, X Zhang, X Liu, C Mao, Y Yan, P Koppula, ... Oncogene 40 (20), 3533-3547, 2021 | 115 | 2021 |
| Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1 Y Zhang, P Koppula, B Gan Cell Cycle 18 (8), 773-783, 2019 | 92 | 2019 |
| BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response F Dai, H Lee, Y Zhang, L Zhuang, H Yao, Y Xi, ZD Xiao, MJ You, W Li, ... Proceedings of the National Academy of Sciences 114 (12), 3192-3197, 2017 | 87 | 2017 |
| BAP1 suppresses tumor development by inducing ferroptosis upon SLC7A11 repression Y Zhang, L Zhuang, B Gan Molecular & cellular oncology 6 (1), 1536845, 2019 | 78 | 2019 |
| NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation X Liu, Y Zhang, L Zhuang, K Olszewski, B Gan Genes & diseases 8 (6), 731-745, 2021 | 65 | 2021 |
| BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21 H Lee, F Dai, L Zhuang, ZD Xiao, J Kim, Y Zhang, L Ma, MJ You, Z Wang, ... Oncotarget 7 (15), 19134, 2016 | 55 | 2016 |
Boyi GanProfessor, MD Anderson Cancer CenterVerified email at mdanderson.org
