Stephen SG Ferguson
Stephen SG Ferguson
University of Ottawa Brain and Mind Institute, Department of Cellular Medicine
Verified email at - Homepage
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Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
SSG Ferguson
Pharmacological reviews 53 (1), 1-24, 2001
β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes
LM Luttrell, S Ferguson, Y Daaka, WE Miller, S Maudsley, GJ Della Rocca, ...
Science 283 (5402), 655-661, 1999
Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
SSG Ferguson, WE Downey III, AM Colapietro, LS Barak, L Ménard, ...
Science 271 (5247), 363-366, 1996
The β2-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis
SA Laporte, RH Oakley, J Zhang, JA Holt, SSG Ferguson, MG Caron, ...
Proceedings of the National Academy of Sciences 96 (7), 3712-3717, 1999
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
Y Daaka, LM Luttrell, S Ahn, GJ Della Rocca, SSG Ferguson, MG Caron, ...
Journal of Biological Chemistry 273 (2), 685-688, 1998
Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness
J Zhang, SSG Ferguson, LS Barak, SR Bodduluri, SA Laporte, PY Law, ...
Proceedings of the National Academy of Sciences 95 (12), 7157-7162, 1998
Dynamin and β-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization
J Zhang, SSG Ferguson, LS Barak, L Ménard, MG Caron
Journal of Biological Chemistry 271 (31), 18302-18305, 1996
A β-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation
LS Barak, SSG Ferguson, J Zhang, MG Caron
Journal of Biological Chemistry 272 (44), 27497-27500, 1997
G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins
SSG Ferguson, LS Barak, J Zhang, MG Caron
Canadian journal of physiology and pharmacology 74 (10), 1095-1110, 1996
Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins
AC Magalhaes, H Dunn, SSG Ferguson
British journal of pharmacology 165 (6), 1717-1736, 2012
Molecular mechanisms of G protein-coupled receptor desensitization and resensitization
SSG Ferguson, J Zhang, LS Barakt, MG Caron
Life sciences 62 (17-18), 1561-1565, 1998
A Central Role for ॆ-Arrestins and Clathrin-coated Vesicle-mediated Endocytosis in ॆ2-Adrenergic Receptor Resensitization: DIFFERENTIAL REGULATION OF RECEPTOR RESENSITIZATION …
J Zhang, LS Barak, KE Winkler, MG Caron, SSG Ferguson
Journal of Biological Chemistry 272 (43), 27005-27014, 1997
Molecular mechanism of desensitization of the chemokine receptor CCR‐5: receptor signaling and internalization are dissociable from its role as an HIV‐1 co‐receptor
I Aramori, J Zhang, SSG Ferguson, PD Bieniasz, BR Cullen, MG Caron
The EMBO journal, 1997
Cellular trafficking of G protein-coupled receptor/β-arrestin endocytic complexes
J Zhang, LS Barak, PH Anborgh, SA Laporte, MG Caron, SSG Ferguson
Journal of Biological Chemistry 274 (16), 10999-11006, 1999
Internal trafficking and surface mobility of a functionally intact β2-adrenergic receptor-green fluorescent protein conjugate
LS Barak, SSG Ferguson, JIE Zhang, C Martenson, T Meyer, MG Caron
Molecular pharmacology 51 (2), 177-184, 1997
Role of Phosphorylation in Agonist-promoted β2-Adrenergic Receptor Sequestration: RESCUE OF A SEQUESTRATION-DEFECTIVE MUTANT RECEPTOR BY βARK1 (∗)
SSG Ferguson, L Ménard, LS Barak, WJ Koch, AM Colapietro, MG Caron
Journal of Biological Chemistry 270 (42), 24782-24789, 1995
HIV‐1‐induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR‐5 co‐receptor
PD Bieniasz, RA Fridell, I Aramori, SSG Ferguson, MG Caron, BR Cullen
The EMBO journal, 1997
Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases
JL Seachrist, SSG Ferguson
Life sciences 74 (2-3), 225-235, 2003
Synergistic regulation of β2-adrenergic receptor sequestration: intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization
L Ménard, SSG Ferguson, J Zhang, FT Lin, RJ Lefkowitz, MG Caron, ...
Molecular pharmacology 51 (5), 800-808, 1997
Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1
J Barlic, JD Andrews, AA Kelvin, SE Bosinger, ME DeVries, L Xu, ...
Nature immunology 1 (3), 227-233, 2000
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