Jan Wildenhain
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The chemical genomic portrait of yeast: uncovering a phenotype for all genes
ME Hillenmeyer, E Fung, J Wildenhain, SE Pierce, S Hoon, W Lee, ...
Science 320 (5874), 362-365, 2008
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ...
Science 318 (5856), 1637-1640, 2007
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
GS Stewart, S Panier, K Townsend, AK Al-Hakim, NK Kolas, ES Miller, ...
Cell 136 (3), 420-434, 2009
BoxPlotR: a web tool for generation of box plots
M Spitzer, J Wildenhain, J Rappsilber, M Tyers
Nature methods 11 (2), 121, 2014
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy
L Ejim, MA Farha, SB Falconer, J Wildenhain, BK Coombes, M Tyers, ...
Nature chemical biology 7 (6), 348-350, 2011
Effects of air temperature on climate-sensitive mortality and morbidity outcomes in the elderly; a systematic review and meta-analysis of epidemiological evidence
A Bunker, J Wildenhain, A Vandenbergh, N Henschke, J Rocklöv, S Hajat, ...
EBioMedicine 6, 258-268, 2016
Chemical genetics reveals a complex functional ground state of neural stem cells
P Diamandis, J Wildenhain, ID Clarke, AG Sacher, J Graham, DS Bellows, ...
Nature chemical biology 3 (5), 268-273, 2007
Cross‐species discovery of syncretic drug combinations that potentiate the antifungal fluconazole
M Spitzer, E Griffiths, KM Blakely, J Wildenhain, L Ejim, L Rossi, ...
Molecular systems biology 7 (1), 499, 2011
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans
AR Burns, IM Wallace, J Wildenhain, M Tyers, G Giaever, GD Bader, ...
Nature chemical biology 6 (7), 549-557, 2010
The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination
L O'Donnell, S Panier, J Wildenhain, JM Tkach, A Al-Hakim, MC Landry, ...
Molecular cell 40 (4), 619-631, 2010
Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast
E Ericson, M Gebbia, LE Heisler, J Wildenhain, M Tyers, G Giaever, ...
PLoS Genet 4 (8), e1000151, 2008
Prediction of synergism from chemical-genetic interactions by machine learning
J Wildenhain, M Spitzer, S Dolma, N Jarvik, R White, M Roy, E Griffiths, ...
Cell systems 1 (6), 383-395, 2015
Combined zebrafish-yeast chemical-genetic screens reveal gene–copper-nutrition interactions that modulate melanocyte pigmentation
H Ishizaki, M Spitzer, J Wildenhain, C Anastasaki, Z Zeng, S Dolma, ...
Disease models & mechanisms 3 (9-10), 639-651, 2010
Reconstructing gene regulatory networks: from random to scale-free connectivity
J Wildenhain, EJ Crampin
IEE Proceedings-Systems Biology 153 (4), 247-256, 2006
A loss of function analysis of host factors influencing vaccinia virus replication by RNA interference
PM Beard, SJ Griffiths, O Gonzalez, IR Haga, TP Jowers, DK Reynolds, ...
PLoS One 9 (6), e98431, 2014
BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID
AG Winter, J Wildenhain, M Tyers
Bioinformatics 27 (7), 1043-1044, 2011
Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30
E Carrillo, G Ben-Ari, J Wildenhain, M Tyers, D Grammentz, TA Lee
Molecular biology of the cell 23 (10), 1928-1942, 2012
A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture
A Ermakov, S Pells, P Freile, VV Ganeva, J Wildenhain, M Bradley, ...
Stem cell research 9 (3), 171-184, 2012
MolClass: a web portal to interrogate diverse small molecule screen datasets with different computational models
J Wildenhain, N FitzGerald, M Tyers
Bioinformatics 28 (16), 2200-2201, 2012
Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism
J Wildenhain, M Spitzer, S Dolma, N Jarvik, R White, M Roy, E Griffiths, ...
Scientific data 3 (1), 1-9, 2016
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Articles 1–20