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Paul M McKeever
Paul M McKeever
Verified email at utoronto.ca
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Year
Isoform‐specific antibodies reveal distinct subcellular localizations of C 9orf72 in amyotrophic lateral sclerosis
S Xiao, L MacNair, P McGoldrick, PM McKeever, JR McLean, M Zhang, ...
Annals of neurology 78 (4), 568-583, 2015
1802015
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
Z Xi, M Zhang, AC Bruni, RG Maletta, R Colao, P Fratta, JM Polke, ...
Acta neuropathologica 129 (5), 715-727, 2015
1582015
MicroRNA Expression Levels Are Altered in the Cerebrospinal Fluid of Patients with Young-Onset Alzheimer’s Disease
PM McKeever, R Schneider, F Taghdiri, A Weichert, N Multani, RA Brown, ...
Molecular Neurobiology, 1-16, 2018
1342018
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
C Laflamme, PM McKeever, R Kumar, J Schwartz, M Kolahdouzan, ...
Elife 8, e48363, 2019
842019
Jump from pre-mutation to pathologic expansion in C9orf72
Z Xi, M van Blitterswijk, M Zhang, P McGoldrick, JR McLean, Y Yunusova, ...
The American Journal of Human Genetics 96 (6), 962-970, 2015
762015
Nodding syndrome in Uganda is a tauopathy
MS Pollanen, S Onzivua, J Robertson, PM McKeever, F Olawa, DL Kitara, ...
Acta neuropathologica 136, 691-697, 2018
632018
C9orf72 isoforms in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
S Xiao, L MacNair, J McLean, P McGoldrick, P McKeever, S Soleimani, ...
Brain research 1647, 43-49, 2016
602016
Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study
R Schneider, P McKeever, TH Kim, C Graff, JC van Swieten, A Karydas, ...
Journal of Neurology, Neurosurgery & Psychiatry 89 (8), 851-858, 2018
572018
DNA methylation age-acceleration is associated with disease duration and age at onset in C9orf72 patients
M Zhang, MC Tartaglia, D Moreno, C Sato, P McKeever, A Weichert, ...
Acta neuropathologica 134, 271-279, 2017
542017
Unaffected mosaic C9orf72 case: RNA foci, dipeptide proteins, but upregulated C9orf72 expression
P McGoldrick, M Zhang, M van Blitterswijk, C Sato, D Moreno, S Xiao, ...
Neurology 90 (4), e323-e331, 2018
502018
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels
S Xiao, PM McKeever, A Lau, J Robertson
Acta neuropathologica communications 7, 1-13, 2019
452019
A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers
M Zhang, R Ferrari, MC Tartaglia, J Keith, EI Surace, U Wolf, C Sato, ...
Brain 141 (10), 2895-2907, 2018
422018
Cholinergic neuron gene expression differences captured by translational profiling in a mouse model of Alzheimer's disease
PM McKeever, TH Kim, AR Hesketh, L MacNair, D Miletic, G Favrin, ...
Neurobiology of aging 57, 104-119, 2017
362017
DNA methylation age acceleration is associated with ALS age of onset and survival
M Zhang, PM McKeever, Z Xi, D Moreno, C Sato, T Bergsma, ...
Acta neuropathologica 139, 943-946, 2020
322020
TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia
H Sidibé, Y Khalfallah, S Xiao, NB Gómez, H Fakim, EMH Tank, ...
Brain 144 (11), 3461-3476, 2021
252021
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72. elife. 2019; 8: 8
C Laflamme, PM McKeever, R Kumar
Publisher Full Text, 0
22
Neuropathologic description of CHCHD10 mutated amyotrophic lateral sclerosis
JL Keith, E Swinkin, A Gao, S Alminawi, M Zhang, P McGoldrick, ...
Neurology: Genetics 6 (1), e394, 2020
162020
The spectrum of disease and tau pathology of nodding syndrome in Uganda
MS Pollanen, S Onzivua, PM McKeever, J Robertson, IR Mackenzie, ...
Brain 146 (3), 954-967, 2023
132023
TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD
H Sidibé, Y Khalfallah, S Xiao, NB Gómez, EMH Tank, G Di Tomasso, ...
bioRxiv, 2020.09. 15.298455, 2020
42020
Single-nucleus multiomic atlas of frontal cortex in amyotrophic lateral sclerosis with a deep learning-based decoding of alternative polyadenylation mechanisms
PM McKeever, AM Sababi, R Sharma, N Khuu, Z Xu, SY Shen, S Xiao, ...
bioRxiv, 2023.12. 22.573083, 2023
12023
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