Regression of established macroscopic liver metastases after in situ transduction of a suicide gene. M Caruso, Y Panis, S Gagandeep, D Houssin, JL Salzmann, D Klatzmann Proceedings of the National Academy of Sciences 90 (15), 7024-7028, 1993 | 538 | 1993 |
Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma. M Caruso, K Pham-Nguyen, YL Kwong, B Xu, KI Kosai, M Finegold, ... Proceedings of the National Academy of Sciences 93 (21), 11302-11306, 1996 | 287 | 1996 |
Selective killing of CD4+ cells harboring a human immunodeficiency virus-inducible suicide gene prevents viral spread in an infected cell population. M Caruso, D Klatzmann Proceedings of the National Academy of Sciences 89 (1), 182-186, 1992 | 126 | 1992 |
Efficient human hematopoietic cell transduction using RD114-and GALV-pseudotyped retroviral vectors produced in suspension and serum-free media K Ghani, X Wang, PO de Campos-Lima, M Olszewska, A Kamen, I Riviere, ... Human gene therapy 20 (9), 966-974, 2009 | 101 | 2009 |
A truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice B Salomon, S Maury, L Loubière, M Caruso, R Onclercq, D Klatzmann Molecular and cellular biology, 1995 | 77 | 1995 |
Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media K Ghani, S Cottin, A Kamen, M Caruso Gene therapy 14 (24), 1705-1711, 2007 | 69 | 2007 |
Enhanced ganciclovir killing and bystander effect of human tumor cells transduced with a retroviral vector carrying a herpes simplex virus thymidine kinase gene mutant J Qiao, ME Black, M Caruso Human gene therapy 11 (11), 1569-1576, 2000 | 63 | 2000 |
A new modified amino acid. 2-Amino-3-mercapto-3-phenylpropionic acid (3-mercaptophenylalanine). Synthesis of derivatives, separation of stereoisomers, and assignment of … O Ploux, M Caruso, G Chassaing, A Marquet The Journal of Organic Chemistry 53 (14), 3154-3158, 1988 | 59 | 1988 |
Gene therapy against cancer and HIV infection using the gene encoding herpes simplex virus thymidine kinase M Caruso Molecular Medicine Today 2 (5), 212-217, 1996 | 48 | 1996 |
Variable efficiency of the thymidine kinase/ganciclovir system in human glioblastoma cell lines: implications for gene therapy FG Sturtz, K Waddell, J Shulok, X Chen, M Caruso, M Sanson, ... Human gene therapy 8 (16), 1945-1953, 1997 | 47 | 1997 |
Gemcitabine intercellular diffusion mediated by gap junctions: new implications for cancer therapy S Cottin, K Ghani, PO de Campos-Lima, M Caruso Molecular cancer 9, 1-10, 2010 | 45 | 2010 |
Gap junctions in human glioblastomas: implications for suicide gene therapy S Cottin, PV Gould, L Cantin, M Caruso Cancer gene therapy 18 (9), 674-681, 2011 | 42 | 2011 |
High translation efficiency is mediated by the encephalomyocarditis virus internal ribosomal entry sites if the natural sequence surrounding the eleventh AUG is retained J Qiao, V Roy, MH Girard, M Caruso Human gene therapy 13 (7), 881-887, 2002 | 42 | 2002 |
VSV-G pseudotyped, MuLV-based, semi-replication-competent retrovirus for cancer treatment J Qiao, J Moreno, L Sanchez-Perez, T Kottke, J Thompson, M Caruso, ... Gene therapy 13 (20), 1457-1470, 2006 | 35 | 2006 |
Expression of a Tat-inducible herpes simplex virus-thymidine kinase gene protectsacyclovir-treated CD4 cells from HIV-1 spread by conditional suicide and inhibition of reverse … M Caruso, B Salomon, S Zhang, E Brisson, F Clavel, I Lowy, D Klatzmann Virology 206 (1), 495-503, 1995 | 31 | 1995 |
Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43 S Cottin, K Ghani, M Caruso Cancer gene therapy 15 (12), 823-831, 2008 | 30 | 2008 |
Retrovirus-mediated gene transfer of the multidrug resistance-associated protein (MRP) cDNA protects cells from chemotherapeutic agents V D'Hondt, M Caruso, A Bank Human gene therapy 8 (15), 1745-1751, 1997 | 25 | 1997 |
A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin V Roy, K Ghani, M Caruso PLoS One 5 (12), e15753, 2010 | 24 | 2010 |
Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia JP Machiels, AS Govaerts, T Guillaume, B Bayat, AM Feyens, E Lenoir, ... Human gene therapy 10 (5), 801-811, 1999 | 24 | 1999 |
Diphtheria toxin mutant CRM197 is an inhibitor of protein synthesis that induces cellular toxicity J Qiao, K Ghani, M Caruso Toxicon 51 (3), 473-477, 2008 | 22 | 2008 |