| Next-generation characterization of the cancer cell line encyclopedia M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ... Nature 569 (7757), 503-508, 2019 | 2371 | 2019 |
| BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma P Bandopadhayay, G Bergthold, B Nguyen, S Schubert, S Gholamin, ... Clinical Cancer Research 20 (4), 912-925, 2014 | 378 | 2014 |
| MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism P Bandopadhayay, LA Ramkissoon, P Jain, G Bergthold, J Wala, R Zeid, ... Nature genetics 48 (3), 273-282, 2016 | 268 | 2016 |
| Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action JM McFarland, BR Paolella, A Warren, K Geiger-Schuller, T Shibue, ... Nature communications 11 (1), 4296, 2020 | 102 | 2020 |
| A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature genetics 53 (4), 529-538, 2021 | 87 | 2021 |
| Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers T Ito, MJ Young, R Li, S Jain, A Wernitznig, JM Krill-Burger, CT Lemke, ... Nature genetics 53 (12), 1664-1672, 2021 | 78 | 2021 |
| Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability BR Paolella, WJ Gibson, LM Urbanski, JA Alberta, TI Zack, ... Elife 6, e23268, 2017 | 78 | 2017 |
| Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities CA Nichols, WJ Gibson, MS Brown, JA Kosmicki, JP Busanovich, H Wei, ... Nature communications 11 (1), 2517, 2020 | 75 | 2020 |
| Id2 is required for specification of dopaminergic neurons during adult olfactory neurogenesis MC Havrda, BT Harris, A Mantani, NM Ward, BR Paolella, VC Cuzon, ... Journal of Neuroscience 28 (52), 14074-14087, 2008 | 56 | 2008 |
| Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells ZJ Reitman, BR Paolella, G Bergthold, K Pelton, S Becker, R Jones, ... Nature communications 10 (1), 3731, 2019 | 53 | 2019 |
| p53 Directly Represses Id2 to Inhibit the Proliferation of Neural Progenitor Cells BR Paolella, MC Havrda, A Mantani, CM Wray, Z Zhang, MA Israel Stem cells 29 (7), 1090-1101, 2011 | 52 | 2011 |
| Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma P Bandopadhayay, F Piccioni, R O’Rourke, P Ho, EM Gonzalez, ... Nature communications 10 (1), 2400, 2019 | 45 | 2019 |
| Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype G Bergthold, P Bandopadhayay, Y Hoshida, S Ramkissoon, ... Neuro-oncology 17 (11), 1486-1496, 2015 | 39 | 2015 |
| Id2 mediates oligodendrocyte precursor cell maturation arrest and is tumorigenic in a PDGF-rich microenvironment MC Havrda, BR Paolella, C Ran, KS Jering, CM Wray, JM Sullivan, ... Cancer research 74 (6), 1822-1832, 2014 | 39 | 2014 |
| Phosphorylation regulates Id2 degradation and mediates the proliferation of neural precursor cells JM Sullivan, MC Havrda, AN Kettenbach, BR Paolella, Z Zhang, ... Stem Cells 34 (5), 1321-1331, 2016 | 29 | 2016 |
| Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in cancers harboring loss of chromosome 18q or 16q JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, A Yang, ... Cell reports 33 (11), 2020 | 28 | 2020 |
| Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer DP Bondeson, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, ... Nature cancer 3 (6), 681-695, 2022 | 26 | 2022 |
| Selective modulation of a pan-essential protein as a therapeutic strategy in cancer CF Malone, NV Dharia, G Kugener, AB Forman, MV Rothberg, ... Cancer discovery 11 (9), 2282-2299, 2021 | 23 | 2021 |
| Behavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in mice MC Havrda, BR Paolella, NM Ward, KB Holroyd Disease Models & Mechanisms 6 (3), 819-827, 2013 | 14 | 2013 |
| Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal JM Krill-Burger, JM Dempster, AA Borah, BR Paolella, DE Root, TR Golub, ... Genome Biology 24 (1), 192, 2023 | 13 | 2023 |
