Sergio Szajnman
Sergio Szajnman
Departamento de Química Orgánica Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires Pabellón 2, Piso 3, Ciudad Universitaria
Verified email at qo.fcen.uba.ar - Homepage
Title
Cited by
Cited by
Year
Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi
E Elhalem, BN Bailey, R Docampo, I Ujváry, SH Szajnman, JB Rodriguez
Journal of medicinal chemistry 45 (18), 3984-3999, 2002
1142002
Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase
SH Szajnman, A Montalvetti, Y Wang, R Docampo, JB Rodriguez
Bioorganic & medicinal chemistry letters 13 (19), 3231-3235, 2003
912003
Synthesis and biological evaluation of 1-amino-1, 1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase
SH Szajnman, EL Ravaschino, R Docampo, JB Rodriguez
Bioorganic & medicinal chemistry letters 15 (21), 4685-4690, 2005
892005
Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation
SH Szajnman, W Yan, BN Bailey, R Docampo, E Elhalem, JB Rodriguez
Journal of medicinal chemistry 43 (9), 1826-1840, 2000
772000
Synthesis and biological evaluation of 2-alkylaminoethyl-1, 1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase
SH Szajnman, GE Garcı, ZH Li, C Jiang, M Galizzi, EJ Bontempi, ...
Bioorganic & medicinal chemistry 16 (6), 3283-3290, 2008
682008
New antibacterials for the treatment of toxoplasmosis; a patent review
JB Rodriguez, SH Szajnman
Expert Opinion on Therapeutic Patents 22 (3), 311-333, 2012
662012
Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi
SH Szajnman, BN Bailey, R Docampo, JB Rodriguez
Bioorganic & medicinal chemistry letters 11 (6), 789-792, 2001
652001
Structure−Activity Relationship of New Growth Inhibitors of Trypanosoma cruzi
GM Cinque, SH Szajnman, L Zhong, R Docampo, AJ Schvartzapel, ...
Journal of medicinal chemistry 41 (9), 1540-1554, 1998
621998
Design, synthesis and biological evaluation of sulfur-containing 1, 1-bisphosphonic acids as antiparasitic agents
M Recher, AP Barboza, ZH Li, M Galizzi, M Ferrer-Casal, SH Szajnman, ...
European journal of medicinal chemistry 60, 431-440, 2013
492013
Synthesis and biological evaluation of new 2-alkylaminoethyl-1, 1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase
VS Rosso, SH Szajnman, L Malayil, M Galizzi, SNJ Moreno, R Docampo, ...
Bioorganic & medicinal chemistry 19 (7), 2211-2217, 2011
482011
Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1, 1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase
S Aripirala, SH Szajnman, J Jakoncic, JB Rodriguez, R Docampo, ...
Journal of medicinal chemistry 55 (14), 6445-6454, 2012
342012
New insights into molecular recognition of 1, 1-bisphosphonic acids by farnesyl diphosphate synthase
M Ferrer-Casal, C Li, M Galizzi, CA Stortz, SH Szajnman, R Docampo, ...
Bioorganic & medicinal chemistry 22 (1), 398-405, 2014
272014
1-(Fluoroalkylidene)-1, 1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase
SH Szajnman, VS Rosso, L Malayil, A Smith, SNJ Moreno, R Docampo, ...
Organic & biomolecular chemistry 10 (7), 1424-1433, 2012
232012
1-(Fluoroalkylidene)-1, 1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase
SH Szajnman, VS Rosso, L Malayil, A Smith, SNJ Moreno, R Docampo, ...
Organic & biomolecular chemistry 10 (7), 1424-1433, 2012
232012
Approaches for designing new potent inhibitors of farnesyl pyrophosphate synthase
JB Rodriguez, BN Falcone, SH Szajnman
Expert opinion on drug discovery 11 (3), 307-320, 2016
222016
New Insights into the Chemistry of gem‐Bis(phosphonates): Unexpected Rearrangement of Michael‐Type Acceptors
SH Szajnman, G García Liñares, P Moro, JB Rodriguez
European journal of organic chemistry 2005 (17), 3687-3696, 2005
202005
Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation
MN Chao, M Storey, C Li, MG Rodríguez, F Di Salvo, SH Szajnman, ...
Bioorganic & medicinal chemistry 25 (24), 6435-6449, 2017
192017
2-alkylaminoethyl-1, 1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase
CA Rodrígues-Poveda, D González-Pacanowska, SH Szajnman, ...
Antimicrobial agents and chemotherapy 56 (8), 4483-4486, 2012
182012
1, 3-Dipolar Cycloadditions of the Versatile Intermediate Tetraethyl Vinylidenebisphosphonate
M Ferrer-Casal, AP Barboza, SH Szajnman, JB Rodriguez
Synthesis 45 (17), 2397-2404, 2013
172013
Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis
ZH Li, C Li, SH Szajnman, JB Rodriguez, SNJ Moreno
Antimicrobial agents and chemotherapy 61 (8), 2017
132017
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