Isabel J. Latorre
Isabel J. Latorre
Scientific Program Manager, Harvard Program in Therapeutic Science
Verified email at - Homepage
TitleCited byYear
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
MB Gerstein, ZJ Lu, EL Van Nostrand, C Cheng, BI Arshinoff, T Liu, ...
Science 330 (6012), 1775-1787, 2010
Differential chromatin marking of introns and expressed exons by H3K36me3
P Kolasinska-Zwierz, T Down, I Latorre, T Liu, XS Liu, J Ahringer
Nature genetics 41 (3), 376, 2009
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ...
Cell 167 (2), 457-470. e13, 2016
An assessment of histone-modification antibody quality
TA Egelhofer, A Minoda, S Klugman, K Lee, P Kolasinska-Zwierz, ...
Nature structural & molecular biology 18 (1), 91, 2011
Comparative analysis of metazoan chromatin organization
JWK Ho, YL Jung, T Liu, BH Alver, S Lee, K Ikegami, KA Sohn, A Minoda, ...
Nature 512 (7515), 449, 2014
Broad chromosomal domains of histone modification patterns in C. elegans
T Liu, A Rechtsteiner, TA Egelhofer, A Vielle, I Latorre, MS Cheung, ...
Genome research 21 (2), 227-236, 2011
Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells
IJ Latorre, MH Roh, KK Frese, RS Weiss, B Margolis, RT Javier
Journal of cell science 118 (18), 4283-4293, 2005
Systematic bias in high-throughput sequencing data and its correction by BEADS
MS Cheung, TA Down, I Latorre, J Ahringer
Nucleic acids research 39 (15), e103-e103, 2011
Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein
KK Frese, SS Lee, DL Thomas, IJ Latorre, RS Weiss, BA Glaunsinger, ...
Oncogene 22 (5), 710, 2003
Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs‐large tumor suppressor
KK Frese, IJ Latorre, SH Chung, G Caruana, A Bernstein, SN Jones, ...
The EMBO journal 25 (6), 1406-1417, 2006
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics
SY Kuo, AB Castoreno, LN Aldrich, KG Lassen, G Goel, V Dančík, ...
Proceedings of the National Academy of Sciences 112 (31), E4281-E4287, 2015
Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo
TB Sundberg, Y Liang, H Wu, HG Choi, ND Kim, T Sim, L Johannessen, ...
ACS chemical biology 11 (8), 2105-2111, 2016
The DREAM complex promotes gene body H2A. Z for target repression
I Latorre, MA Chesney, JM Garrigues, P Stempor, A Appert, ...
Genes & development 29 (5), 495-500, 2015
Discovery of a small-molecule probe for V-ATPase function
LN Aldrich, SY Kuo, AB Castoreno, G Goel, P Kuballa, MG Rees, ...
Journal of the American Chemical Society 137 (16), 5563-5568, 2015
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells
L Johannessen, TB Sundberg, DJ O'Connell, R Kolde, J Berstler, ...
Nature chemical biology 13 (10), 1102, 2017
Simultaneous pathway activity inference and gene expression analysis using RNA sequencing
DJ O’Connell, R Kolde, M Sooknah, DB Graham, TB Sundberg, IJ Latorre, ...
Cell systems 2 (5), 323-334, 2016
Tight junction proteins and cancer
IJ Latorre, KK Frese, RT Javier
Tight Junctions, 116-134, 2006
Selective induction of homeostatic Th17 cells in the murine intestine by cholera toxin interacting with the microbiota
Q Zhao, SN Harbour, R Kolde, IJ Latorre, HM Tun, TR Schoeb, H Turner, ...
The Journal of Immunology 199 (1), 312-322, 2017
Spatial and temporal mapping of human innate lymphoid cells reveals elements of tissue specificity
NA Yudanin, F Schmitz, AL Flamar, JJC Thome, ET Wojno, JB Moeller, ...
Immunity 50 (2), 505-519. e4, 2019
Repurposing mitochondria from ATP production to ROS generation drives a pro-inflammatory phenotype in macrophages that depends on succinate oxidation by complex II
EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ...
Cell 167 (2), 457, 2016
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