Jochen Weile

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Frederick P (Fritz) RothUniversity of Toronto & Mt Sinai HospitalVerified email at utoronto.ca
Atina CoteLunenfeld Tanenbaum Research InstituteVerified email at lunenfeld.ca
Douglas M FowlerUniversity of WashingtonVerified email at uw.edu
Jan BaumbachUniversity of HamburgVerified email at uni-hamburg.de
Anil WipatProfessor of Bioinformatics Newcastle UniversityVerified email at ncl.ac.uk
Yingzhou WuUniversity of TorontoVerified email at mail.utoronto.ca
Simon CockellSenior Lecturer, School of Biomedical, Nutritional and Sports Sciences, Newcastle UniversityVerified email at newcastle.ac.uk
Phillip LordLecturer in Computing Science, Newcastle UniversityVerified email at newcastle.ac.uk
Darren WilkinsonProfessor of Stochastic Modelling, Newcastle University, U.K.Verified email at ncl.ac.uk
Patrick AloyICREA Research Professor at the Institute for Research in BiomedicineVerified email at irbbarcelona.org
Alan F RubinWalter and Eliza Hall Institute of Medical Research Verified email at wehi.edu.au
Matthew PocockComputing Science, Newcastle UniversityVerified email at ncl.ac.uk
Murat TasanRsearch Fellow, University of TorontoVerified email at utoronto.ca
Fan YangPathology, Stanford UniveristyVerified email at stanford.edu
Carles PonsInstitute for Research in BiomedicineVerified email at irbbarcelona.org
Jennifer HallinanSenior Lecturer, Department of Biological Sciences, Macquarie UniversityVerified email at mq.edu.au
Gary BaderProfessor of Molecular Genetics and Computer Science, The Donnelly Centre, University of TorontoVerified email at utoronto.ca
George S KaragiannisDepartment of Microbiology & Immunology, Albert Einstein College of MedicineVerified email at einsteinmed.org
Artem LysenkoRIKENVerified email at postman.riken.jp
Matthew M. HindlePostdoctoral Researcher, University of EdinburghVerified email at ed.ac.uk

Jochen Weile

University of Toronto

Verified email at mail.utoronto.ca

Deep Mutational Scanning Protein-protein interaction Systems biology Computational biology


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Widespread macromolecular interaction perturbations in human genetic disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015	373	2015
A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020	200*	2020
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics N Yachie, E Petsalaki, JC Mellor, J Weile, Y Jacob, M Verby, SB Ozturk, ... Molecular systems biology 12 (4), 863, 2016	79	2016
A framework for exhaustively mapping functional missense variants J Weile, S Sun, AG Cote, J Knapp, M Verby, JC Mellor, Y Wu, C Pons, ... Molecular systems biology 13 (12), 957, 2017	74	2017
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation GS Karagiannis, J Weile, GD Bader, J Minta BMC cardiovascular disorders 13 (1), 1-19, 2013	56	2013
KeyPathwayMiner: detecting case-specific biological pathways using expression data N Alcaraz, H Kücük, J Weile, A Wipat, J Baumbach Internet Mathematics 7 (4), 299-313, 2011	53	2011
Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas J Weile, FP Roth Human genetics 137 (9), 665-678, 2018	44	2018
MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ... Genome biology 20 (1), 1-11, 2019	36	2019
An integrated dataset for in silico drug discovery SJ Cockell, J Weile, P Lord, C Wipat, D Andriychenko, M Pocock, ... Journal of integrative bioinformatics 7 (3), 15-27, 2010	36	2010
Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics JJ Díaz‐Mejía, A Celaj, JC Mellor, A Coté, A Balint, B Ho, P Bansal, ... Molecular systems biology 14 (5), e7985, 2018	21	2018
CoryneRegNet 2: an integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes J Baumbach, K Brinkrolf, T Wittkop, A Tauch, S Rahmann Journal of Integrative Bioinformatics 3 (2), 1-13, 2006	21*	2006
Bayesian integration of networks without gold standards J Weile, K James, J Hallinan, SJ Cockell, P Lord, A Wipat, D Wilkinson Bioinformatics 28 (11), 1495-1500, 2012	16	2012
CoryneCenter–an online resource for the integrated analysis of corynebacterial genome and transcriptome data H Neuweger, J Baumbach, S Albaum, T Bekel, M Dondrup, AT Hüser, ... BMC systems biology 1 (1), 1-12, 2007	15	2007
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase S Sun, J Weile, M Verby, Y Wu, Y Wang, AG Cote, I Fotiadou, ... Genome medicine 12 (1), 1-18, 2020	12	2020
Assessing predictions of fitness effects of missense mutations in SUMO‐conjugating enzyme UBE2I J Zhang, LN Kinch, Q Cong, J Weile, S Sun, AG Cote, FP Roth, NV Grishin Human mutation 38 (9), 1051-1063, 2017	12	2017
Customizable views on semantically integrated networks for systems biology J Weile, M Pocock, SJ Cockell, P Lord, JM Dewar, EM Holstein, ... Bioinformatics 27 (9), 1299-1306, 2011	11	2011
Linking life sciences data using graph-based mapping J Taubert, M Hindle, A Lysenko, J Weile, J Köhler, CJ Rawlings International Workshop on Data Integration in the Life Sciences, 16-30, 2009	7	2009
A web application and service for imputing and visualizing missense variant effect maps Y Wu, J Weile, AG Cote, S Sun, J Knapp, M Verby, FP Roth Bioinformatics 35 (17), 3191-3193, 2019	6	2019
Systematic analysis of bypass suppression of essential genes J van Leeuwen, C Pons, G Tan, JZ Wang, J Hou, J Weile, M Gebbia, ... Molecular systems biology 16 (9), e9828, 2020	5	2020
Assessing predictions on fitness effects of missense variants in calmodulin J Zhang, LN Kinch, Q Cong, P Katsonis, O Lichtarge, C Savojardo, ... Human mutation 40 (9), 1463-1473, 2019	4	2019

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