Jonathan Strecker
Jonathan Strecker
Broad Institute of MIT & Harvard
Verified email at
Cited by
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Mitosis inhibits DNA double-strand break repair to guard against telomere fusions
A Orthwein, A Fradet-Turcotte, SM Noordermeer, MD Canny, CM Brun, ...
Science 344 (6180), 189-193, 2014
RNA-guided DNA insertion with CRISPR-associated transposases
J Strecker, A Ladha, Z Gardner, JL Schmid-Burgk, KS Makarova, ...
Science 365 (6448), 48-53, 2019
Engineering of CRISPR-Cas12b for human genome editing
J Strecker, S Jones, B Koopal, J Schmid-Burgk, B Zetsche, L Gao, ...
Nature communications 10 (1), 1-8, 2019
DNA damage signalling targets the kinetochore to promote chromatin mobility
J Strecker, GD Gupta, W Zhang, M Bashkurov, MC Landry, L Pelletier, ...
Nature cell biology 18 (3), 281-290, 2016
Perinuclear tethers license telomeric DSBs for a broad kinesin-and NPC-dependent DNA repair process
DKC Chung, JNY Chan, J Strecker, W Zhang, S Ebrahimi-Ardebili, T Lu, ...
Nature communications 6 (1), 1-13, 2015
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system
LCK Wan, DYL Mao, D Neculai, J Strecker, D Chiovitti, I Kurinov, G Poda, ...
Nucleic acids research 41 (12), 6332-6346, 2013
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
R Oshidari, J Strecker, DKC Chung, KJ Abraham, JNY Chan, CJ Damaren, ...
Nature communications 9 (1), 1-11, 2018
LAMP-Seq: population-scale COVID-19 diagnostics using a compressed barcode space
JL Schmid-Burgk, D Li, D Feldman, M Slabicki, J Borrajo, J Strecker, ...
biorxiv, 2020
A survey of genome editing activity for 16 Cas12a orthologs
B Zetsche, J Strecker, OO Abudayyeh, JS Gootenberg, DA Scott, F Zhang
The Keio journal of medicine, 2019
Therapeutic potential of egg yolk antibodies for treating Clostridium difficile infection
GL Mulvey, TC Dingle, L Fang, J Strecker, GD Armstrong
Journal of medical microbiology 60 (8), 1181-1187, 2011
Highly parallel profiling of Cas9 variant specificity
JL Schmid-Burgk, L Gao, D Li, Z Gardner, J Strecker, B Lash, F Zhang
Molecular cell 78 (4), 794-800. e8, 2020
High-resolution structure of Cas13b and biochemical characterization of RNA targeting and cleavage
IM Slaymaker, P Mesa, MJ Kellner, S Kannan, E Brignole, J Koob, ...
Cell reports 26 (13), 3741-3751. e5, 2019
A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres
J Strecker, S Stinus, MP Caballero, RK Szilard, M Chang, D Durocher
Elife 6, e23783, 2017
From alpha to beta: identification of amino acids required for the N‐acetyllactosamine‐specific lectin‐like activity of bundlin
RM Humphries, MS Donnenberg, J Strecker, E Kitova, JS Klassen, L Cui, ...
Molecular microbiology 72 (4), 859-868, 2009
Lipopolysaccharide renders transgenic mice expressing human serum amyloid P component sensitive to Shiga toxin 2
TP Griener, JG Strecker, RM Humphries, GL Mulvey, C Fuentealba, ...
PLoS One 6 (6), e21457, 2011
Response to Comment on “RNA-guided DNA insertion with CRISPR-associated transposases”
J Strecker, A Ladha, KS Makarova, EV Koonin, F Zhang
Science 368 (6495), 2020
Crispr-associated transposase systems and methods of use thereof
F Zhang, J Strecker, A Ladha
US Patent App. 16/717,713, 2020
Dual modes of CRISPR-associated transposon homing
M Saito, A Ladha, J Strecker, G Faure, E Neumann, H Altae-Tran, ...
Cell, 2021
High-resolution structure of cas13b and biochemical characterization of RNA targeting and cleavage
IM Slaymaker, P Mesa, MJ Kellner, S Kannan, E Brignole, J Koob, ...
Cell Reports 34 (10), 2021
Novel crispr enzymes and systems
F Zhang, B Zetsche, J Strecker
US Patent App. 16/773,000, 2020
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