Alejandra del Carmen Alonso
Alejandra del Carmen Alonso
Staten Island, NY
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Tau pathology in Alzheimer disease and other tauopathies
K Iqbal, AC Alonso, S Chen, MO Chohan, E El-Akkad, CX Gong, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1739 (2-3 …, 2005
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AC Alonso, T Zaidi, M Novak, I Grundke-Iqbal, K Iqbal
Proceedings of the National Academy of Sciences 98 (12), 6923-6928, 2001
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
AC Alonso, I Grundke-Iqbal, K Iqbal
Nature medicine 2 (7), 783-787, 1996
Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease.
E Köpke, YC Tung, S Shaikh, AC Alonso, K Iqbal, I Grundke-Iqbal
Journal of Biological Chemistry 268 (32), 24374-24384, 1993
Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease.
AC Alonso, T Zaidi, I Grundke-Iqbal, K Iqbal
Proceedings of the National Academy of Sciences 91 (12), 5562-5566, 1994
Mechanisms of tau-induced neurodegeneration
K Iqbal, F Liu, CX Gong, AC Alonso, I Grundke-Iqbal
Acta neuropathologica 118, 53-69, 2009
Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of …
AC Alonso, I Grundke-Iqbal, HS Barra, K Iqbal
Proceedings of the national academy of sciences 94 (1), 298-303, 1997
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations
AC Alonso, A Mederlyova, M Novak, I Grundke-Iqbal, K Iqbal
Journal of Biological Chemistry 279 (33), 34873-34881, 2004
Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration
AD Alonso, J Di Clerico, B Li, CP Corbo, ME Alaniz, I Grundke-Iqbal, ...
Journal of Biological Chemistry 285 (40), 30851-30860, 2010
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
AC Alonso, B Li, I Grundke-Iqbal, K Iqbal
Proceedings of the National Academy of Sciences 103 (23), 8864-8869, 2006
Hyperphosphorylation of tau associates with changes in its function beyond microtubule stability
AD Alonso, LS Cohen, C Corbo, V Morozova, A ElIdrissi, G Phillips, ...
Frontiers in cellular neuroscience 12, 338, 2018
Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in VitroPhosphorylation into the disease-like protein
AC Alonso, T Zaidi, M Novak, HS Barra, I Grundke-Iqbal, K Iqbal
Journal of Biological Chemistry 276 (41), 37967-37973, 2001
Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles
K Iqbal, A del C. Alonso, CX Gong, S Khatoon, JJ Pei, JZ Wang, ...
Ageing and Dementia, 169-180, 1998
Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies
AC Alonso, B Li, I Grundke-Iqbal, K Iqbal
Current Alzheimer Research 5 (4), 375-384, 2008
Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss
J Di, LS Cohen, CP Corbo, GR Phillips, A El Idrissi, AD Alonso
Scientific reports 6 (1), 20833, 2016
Fluorescent porous carbon nanocapsules for two-photon imaging, NIR/pH dual-responsive drug carrier, and photothermal therapy
H Wang, Y Sun, J Yi, J Fu, J Di, A del Carmen Alonso, S Zhou
Biomaterials 53, 117-126, 2015
Tau-induced neurodegeneration: mechanisms and targets
C Beharry, LS Cohen, J Di, K Ibrahim, S Briffa-Mirabella, AC Alonso
Neuroscience bulletin 30, 346-358, 2014
Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach
K Iqbal, AC Del Alonso, JA Gondal, CX Gong, N Haque, S Khatoon, ...
Advances in Dementia Research, 213-222, 2000
Mechanism of neurofibrillary degeneration in Alzheimer's disease
K Iqbal, AC Alonso, CX Gong, S Khatoon, TJ Singh, I Grundke-Iqbal
Molecular neurobiology 9, 119-123, 1994
“Clicked” sugar–curcumin conjugate: modulator of amyloid-β and tau peptide aggregation at ultralow concentrations
S Dolai, W Shi, C Corbo, C Sun, S Averick, D Obeysekera, M Farid, ...
ACS chemical neuroscience 2 (12), 694-699, 2011
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