Substituted isoquinolines by Noyori transfer hydrogenation: Enantioselective synthesis of chiral diamines containing an aniline subunit E Vedejs, P Trapencieris, E Suna The Journal of Organic Chemistry 64 (18), 6724-6729, 1999 | 127 | 1999 |
Prognostic relevance of carbonic anhydrase IX expression is distinct in various subtypes of breast cancer and its silencing suppresses self-renewal capacity of breast cancer cells L Ivanova, E Zandberga, K Siliņa, Z Kalniņa, A Ābols, E Endzeliņš, ... Cancer chemotherapy and pharmacology 75, 235-246, 2015 | 60 | 2015 |
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells E Miele, S Valente, V Alfano, M Silvano, P Mellini, D Borovika, B Marrocco, ... Oncotarget 8 (40), 68557, 2017 | 52 | 2017 |
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit K Jaudzems, K Tars, G Maurops, N Ivdra, M Otikovs, J Leitans, ... ACS medicinal chemistry letters 5 (4), 373-377, 2014 | 51 | 2014 |
Untitled WO Patent 2006077365:A1, 0 | 46* | |
Facile synthesis of coumarin bioisosteres—1, 2-benzoxathiine 2, 2-dioxides A Grandane, S Belyakov, P Trapencieris, R Zalubovskis Tetrahedron 68 (27-28), 5541-5546, 2012 | 42 | 2012 |
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells P Mellini, B Marrocco, D Borovika, L Polletta, I Carnevale, S Saladini, ... Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 27 | 2018 |
Novel melanocortin receptor agonists and antagonists T Lundstedt, A Skottner, E Seifert, I Starchenkov, P Trapencieris, V Kauss, ... US Patent App. 10/182,192, 2003 | 24 | 2003 |
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli PA Lang, A Parkova, TM Leissing, K Calvopiña, R Cain, A Krajnc, ... Biomolecules 10 (6), 899, 2020 | 23 | 2020 |
Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors G De Simone, G Pizika, SM Monti, A Di Fiore, J Ivanova, I Vozny, ... Biomed Research International 2014, 2014 | 22 | 2014 |
Broad spectrum β-lactamase inhibition by a thioether substituted bicyclic boronate A Parkova, A Lucic, A Krajnc, J Brem, K Calvopina, GW Langley, ... ACS Infectious Diseases 6 (6), 1398-1404, 2019 | 20 | 2019 |
Morphological and immunohistochemical profile of pancreatic neuroendocrine neoplasms Z Simtniece, A Vanags, I Strumfa, M Sperga, E Vasko, P Prieditis, ... Polish Journal of Pathology 66 (2), 176-194, 2015 | 18 | 2015 |
Hypothetical gamma-butyrobetaine esterase-dependent signal transduction system: possible link to mildronate action I Kalvinsh, A Gutcaits, L Bagdoniene, D Labeikyte, P Trapencieris, ... Med Hypotheses Res 3, 803-12, 2006 | 17 | 2006 |
Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors R Recacha, J Leitans, I Akopjana, L Aprupe, P Trapencieris, K Jaudzems, ... Acta Crystallographica Section F: Structural Biology Communications 71 (12 …, 2015 | 16 | 2015 |
Depletion of carbonic anhydrase IX abrogates hypoxia-induced overexpression of stanniocalcin-1 in triple negative breast cancer cells E Zandberga, P Zayakin, A Ābols, D Pūpola, P Trapencieris, A Linē Cancer biology & therapy 18 (8), 596-605, 2017 | 15 | 2017 |
Saccharin sulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII V Morkūnaitė, L Baranauskienė, A Zubrienė, V Kairys, J Ivanova, ... BioMed Research International 2014, 2014 | 15 | 2014 |
A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasion, angiogenesis and targets ERK1/2 phosphorylation N Romanchikova, P Trapencieris, J Zemītis, M Turks Journal of Enzyme Inhibition and Medicinal Chemistry 29 (6), 765-772, 2014 | 14 | 2014 |
Discovery of aziridine-triazole conjugates as selective MMP-2 inhibitors I Kreituss, E Rozenberga, J Zemītis, P Trapencieris, N Romanchikova, ... Chemistry of Heterocyclic Compounds 49, 1108-1117, 2013 | 14 | 2013 |
Synthesis of small and medium size monocyclic hydroxamic acids P Trapencieris, J Strazdina, P Bertrand Chemistry of Heterocyclic Compounds 48, 833-855, 2012 | 14 | 2012 |
The Odyssey of the ancestral Escherich strain through culture collections: an example of allopatric diversification M Desroches, G Royer, D Roche, M Mercier-Darty, D Vallenet, C Médigue, ... Msphere 3 (1), 10.1128/msphere. 00553-17, 2018 | 12 | 2018 |